Li Yongguo相关文献与解析，生知库 | 链接生命科学的每一步

Increasing in vivo drug exposure levels of compound WX-081 (sudapyridine) when used in combination with clofazimine or clarithromycin

当与氯法齐明或克拉霉素联合使用时，可提高化合物 WX-081（苏达吡啶）的体内药物暴露水平。

期刊:Microbiology Spectrum

影响因子:3.8

doi:10.1128/spectrum.01555-25

Wang, Xueyu; Gao, Shan; Yu, Xia; Li, Yongguo; Li, Lei; Chu, Naihui; Huang, Hairong; Nie, Wenjuan

发表日期：2026

文献求助收藏

Therapeutic management of PI3KÎ± inhibitor-induced hyperglycemia with a novel glucokinase activator: Advancing the Frontier of PI3KÎ± inhibitor therapy.

利用新型葡萄糖激酶激活剂治疗PI3Kα抑制剂引起的血糖升高：推进PI3Kα抑制剂治疗的前沿

期刊:Molecular Metabolism

影响因子:6.6

doi:10.1016/j.molmet.2025.102151

Jin Guanqin, Liu Shihuang, Zheng Kewei, Cheng Xiaobo, Chai Ranran, Ye Wei, Wei Wei, Li Yongguo, Huang Ai, Li Guiling, Yi Huan, Kang Yu

Environmental and Rhizosphere Microbiome Drivers of Metabolic Profiles in Gastrodia elata: An Integrative Analysis of Soil, Metabolomics and Anti-Inflammatory Readouts

环境和根际微生物组对天麻代谢谱的影响：土壤、代谢组学和抗炎指标的综合分析

期刊:Foods

影响因子:5.1

doi:10.3390/foods14244265

Yang, Yan; Guo, Longxing; Li, Yongguo; Ji, Miaomiao; He, Tingting; Hou, Kaiming; Li, Jian; Zhang, Haonan; Shi, Zhilong; Zhang, Haizhu

Population pharmacokinetic and exposure-response study of a novel anti-tuberculosis drug to inform its dosage design in phase III clinical trial

一项新型抗结核药物的群体药代动力学和暴露-反应研究，旨在指导其在 III 期临床试验中的剂量设计。

期刊:European Journal of Pharmaceutical Sciences

影响因子:4.7

doi:10.1016/j.ejps.2025.107160

Kong, Weijie; Liang, Hao; Zhang, Yi; Li, Lei; Li, Yongguo; Yan, Xiaoyu; Liu, Dongyang

发表日期：2025

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Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from Gastrodia elata: A Review

天麻多糖的提取、纯化、结构特征、生物活性及应用：综述

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules30020262

Yang, Yan; Hai, Yonglin; Yang, Yongcheng; Wen, Rouyuan; Wang, Le; Qian, Yan; Zhang, Jiaxian; Li, Yongguo; Shi, Zhilong; Zhang, Haizhu

发表日期：2025

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The TBLR1/TBL1 Co-Factor Complex Acts as a Transcriptional Checkpoint in the Brown Adipose Tissue Response to Prolonged Cold Exposure.

TBLR1/TBL1 辅因子复合物在棕色脂肪组织对长期寒冷暴露的反应中起转录检查点的作用

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.202402993RRR

KÃ¶ker Sahika Cingir, Tsokanos Foivos-Filippos, El-Merahbi Rabih, Jha Ankush Kumar, Cicatelli Karin, Weber Peter, Mhamane Amit, Kaltenecker Doris, Morigny Pauline, Loft Anne, Klepac Katarina, Maida Adriano, Molocea Claudia-Eveline, Hass Daniela, Vogl Elena Sophie, Alfaro Ana Jimena, Sun Wenfei, Zitzelsberger Horst, Unger Kristian, SzendrÃ¶di Julia, Li Yongguo, Diaz Mauricio Berriel, Wolfrum Christian, Bartelt Alexander, Herzig Stephan, Georgiadi Anastasia

TNF-Î± inhibits Epstein Barr virus reactivation through the GPX4 mediated glutathione pathway.

TNF-α通过GPX4介导的谷胱甘肽途径抑制Epstein Barr病毒的再激活

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-98679-5

Zhang Youyu, Wu Yilin, Ding Beining, Li Qian, Chen Xuenuo, Liu Huiling, Xu Mingyan, Lan Yinghua, Li Yongguo

信号转导

发表日期：2025

文献求助收藏

[Retracted] Hepatitis B core antigen regulates dendritic cell proliferation and apoptosis through regulation of PKC/NF‑κB signaling pathway

【已撤稿】乙型肝炎核心抗原通过调控PKC/NF-κB信号通路来调节树突状细胞的增殖和凋亡

期刊:Molecular Medicine Reports

影响因子:3.5

doi:10.3892/mmr.2025.13651

Liu, Lan; Huang, Yanxin; Zhang, Kaili; Song, Shupeng; Li, Shuangxing; Li, Yongguo; Lan, Yinghua

Correlation between Epstein-Barr virus and anti-cytomegalovirus/-herpes simplex virus/-Toxoplasma gondii antibodies in Chongqing, China: a cross-sectional observational study

中国重庆市EB病毒与抗巨细胞病毒/单纯疱疹病毒/弓形虫抗体相关性研究：一项横断面观察性研究

期刊:Frontiers in Medicine

影响因子:3

doi:10.3389/fmed.2025.1661969

Zhang, Youyu; Song, Shupeng; Wu, Yilin; Ding, Beining; Chen, Xuenuo; Li, Qian; Du, Yuxia; Liu, Huiling; Li, Yongguo

Transcriptional and epigenetic control of human naÃ¯ve CD8(+) T cell activation.

人类幼稚CD8(+) T细胞活化的转录和表观遗传控制。

Increasing in vivo drug exposure levels of compound WX-081 (sudapyridine) when used in combination with clofazimine or clarithromycin

当与氯法齐明或克拉霉素联合使用时，可提高化合物 WX-081（苏达吡啶）的体内药物暴露水平。

Therapeutic management of PI3KÎ± inhibitor-induced hyperglycemia with a novel glucokinase activator: Advancing the Frontier of PI3KÎ± inhibitor therapy.

利用新型葡萄糖激酶激活剂治疗PI3Kα抑制剂引起的血糖升高：推进PI3Kα抑制剂治疗的前沿

Environmental and Rhizosphere Microbiome Drivers of Metabolic Profiles in Gastrodia elata: An Integrative Analysis of Soil, Metabolomics and Anti-Inflammatory Readouts

环境和根际微生物组对天麻代谢谱的影响：土壤、代谢组学和抗炎指标的综合分析

Population pharmacokinetic and exposure-response study of a novel anti-tuberculosis drug to inform its dosage design in phase III clinical trial

一项新型抗结核药物的群体药代动力学和暴露-反应研究，旨在指导其在 III 期临床试验中的剂量设计。

Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from Gastrodia elata: A Review

天麻多糖的提取、纯化、结构特征、生物活性及应用：综述

The TBLR1/TBL1 Co-Factor Complex Acts as a Transcriptional Checkpoint in the Brown Adipose Tissue Response to Prolonged Cold Exposure.

TBLR1/TBL1 辅因子复合物在棕色脂肪组织对长期寒冷暴露的反应中起转录检查点的作用

TNF-Î± inhibits Epstein Barr virus reactivation through the GPX4 mediated glutathione pathway.

TNF-α通过GPX4介导的谷胱甘肽途径抑制Epstein Barr病毒的再激活

[Retracted] Hepatitis B core antigen regulates dendritic cell proliferation and apoptosis through regulation of PKC/NF‑κB signaling pathway

【已撤稿】乙型肝炎核心抗原通过调控PKC/NF-κB信号通路来调节树突状细胞的增殖和凋亡

Correlation between Epstein-Barr virus and anti-cytomegalovirus/-herpes simplex virus/-Toxoplasma gondii antibodies in Chongqing, China: a cross-sectional observational study

中国重庆市EB病毒与抗巨细胞病毒/单纯疱疹病毒/弓形虫抗体相关性研究：一项横断面观察性研究