文献库，生知库 | 链接生命科学的每一步

日期影响因子

Engineering integrin αvβ8-targeted extracellular vesicles to deliver BDNF mRNA for motor recovery in spinal cord injury

构建靶向整合素αvβ8的细胞外囊泡，以递送BDNF mRNA促进脊髓损伤后的运动功能恢复

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-026-04222-7

Shie, Ming-You; Chiu, Cheng-Di; Chen, Yeh; Lin, Yen-Hong; Yu, Min-Hua; Chiu, You-Pen; Chiu, Po-Fan; Chen, Cheng-Yu; Chen, Yi-Wen; Chen, Mei-Chih; Cho, Der-Yang

细胞生物学

发表日期：2026

文献求助收藏

Engineering HLA-G-targeted extracellular vesicles nanoplatform for enhanced cancer therapy through precise cancer drug delivery.

构建靶向 HLA-G 的细胞外囊泡纳米平台，通过精准的癌症药物递送增强癌症治疗效果。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-66451-y

Shie Ming-You, Huang Shi-Wei, Chen Yeh, Chen Mei-Chih, Pan Chih-Ming, Chen Cheng-Yu, Lin Yen-Hong, Yu Min-Hua, Kan Kai-Wen, Chiu Shao-Chih, Ho Hui-Chun, Chen Yi-Wen, Cho Der-Yang

细胞生物学

发表日期：2025

文献求助收藏

Engineered extracellular vesicles-mediated curcumin delivery in brain microenvironment modulating lysosomes, mitochondria, and microglia reprogram for parkinson's disease therapy

利用工程化细胞外囊泡介导的姜黄素递送系统，在大脑微环境中调节溶酶体、线粒体和小胶质细胞的重编程，从而治疗帕金森病。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-025-03911-z

Shie, Ming-You; Chen, Mei-Chih; Chen, Yeh; Huang, Shi-Wei; Lin, Yen-Hong; Yu, Min-Hua; Pan, Chih-Ming; Chen, Cheng-Yu; Chen, Yi-Wen; Hsieh, Ching-Liang; Chiu, Shao-Chih; Kao, Shung-Te; Lin, Jaung-Geng; Cho, Der-Yang

细胞生物学

发表日期：2025

文献求助收藏

Lithium-doped calcium silicate scaffolds-activated M2-polarized macrophage-derived miR-145-5p-riched extracellular vesicles to enhance osteoimmunomodulation for accelerating bone regeneration

锂掺杂硅酸钙支架激活M2极化巨噬细胞来源的富含miR-145-5p的细胞外囊泡，从而增强骨免疫调节，加速骨再生

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-025-03679-2

Kuo, Ting-You; Lin, Tsung-Li; Lin, Yen-Hong; Chen, Cheng-Yu; Cho, Der-Yang; Chen, Yi-Wen; Shie, Ming-You

细胞生物学

免疫/内分泌

发表日期：2025

文献求助收藏

Osteoimmunomodulation of astragalus-calcium silicate scaffolds-activated M2 macrophage-derived miR-218-rich exosome for enhanced bone regeneration

黄芪-硅酸钙支架激活M2巨噬细胞来源的富含miR-218的外泌体，从而增强骨再生，发挥骨免疫调节作用

期刊:Materials Today Bio

影响因子:10.2

doi:10.1016/j.mtbio.2025.102286

Chen, Cheng-Yu; Lee, Jian-Jr; Lin, Yen-Hong; Kuo, Ting-You; Cho, Der-Yang; Shie, Ming-You

细胞生物学

免疫/内分泌

发表日期：2025

文献求助收藏

Mitochondrial biogenesis modulation by silicon-stimulated mesenchymal stem cells-derived extracellular vesicles drives angio- and lymphangiogenesis in chronic wound healing.

硅刺激间充质干细胞衍生的细胞外囊泡调节线粒体生物合成，从而驱动慢性伤口愈合中的血管生成和淋巴管生成。

期刊:Materials Today Bio

影响因子:10.2

doi:10.1016/j.mtbio.2025.102629

Yu Min-Hua, Lin Yen-Hong, Liu En-Wei, Hsu-Jiang Tai-Yi, Cho Der-Yang, Lee Jian-Jr, Shie Ming-You

发育与干细胞

发表日期：2025

文献求助收藏

Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration

锂掺杂硅酸钙水泥调节免疫微环境，促进M2型巨噬细胞极化，从而增强骨再生。

期刊:Journal of Biological Engineering

影响因子:6.5

doi:10.1186/s13036-024-00467-8

Lin, Yen-Hong; Chen, Cheng-Yu; Chen, Kun-Hao; Kuo, Ting-You; Lin, Tsung-Li; Shie, Ming-You

细胞生物学

免疫/内分泌

发表日期：2025

文献求助收藏

3D-printed magnesium/strontium-co-doped calcium silicate scaffolds promote angiogenesis and bone regeneration through synergistic bioactive ion stimulation.

3D打印的镁/锶共掺杂硅酸钙支架通过协同生物活性离子刺激促进血管生成和骨再生

期刊:Journal of Biological Engineering

影响因子:6.5

doi:10.1186/s13036-025-00528-6

Ho Chia-Che, Hsu Tuan-Ti, Chiu Yung-Cheng, Lin Yen-Hong, Xie Pei-Cheng, Wang Chen-Ying

发表日期：2025

文献求助收藏

The exosomal secretomes of mesenchymal stem cells extracted via 3D-printed lithium-doped calcium silicate scaffolds promote osteochondral regeneration

通过 3D 打印锂掺杂硅酸钙支架提取的间充质干细胞外泌体分泌物促进骨软骨再生

期刊:Materials Today Bio

影响因子:8.7

doi:10.1016/j.mtbio.2023.100728

Tsung-Li Lin, Yen-Hong Lin, Alvin Kai-Xing Lee, Ting-You Kuo, Cheng-Yu Chen, Kun-Hao Chen, Yun-Ting Chou, Yi-Wen Chen, Ming-You Shie

发育与干细胞

发表日期：2023

文献求助收藏

Enhancing the Mechanical Properties and Aging Resistance of 3D-Printed Polyurethane through Polydopamine and Graphene Coating

通过聚多巴胺和石墨烯涂层增强3D打印聚氨酯的机械性能和耐老化性能

期刊:Polymers

影响因子:4.9

doi:10.3390/polym15183744

Tung, Chien-Chiang; Lin, Yen-Hong; Chen, Yi-Wen; Wang, Fu-Ming

发表日期：2023

文献求助收藏