An innovative engineered IL-10 monomer strengthens T cell-mediated anti-tumor responses through anti-PD-1 cis-delivery.
一种创新的工程化IL-10单体通过抗PD-1顺式递送增强T细胞介导的抗肿瘤反应。
期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102515
Gu Ce, Guo Jian, Zhou Chang, Hu Peipei, Wu Xiaodong, Ding Jiaojiao, Zhou Xinxin, Zeng Liao, Yu Wen, Ou Yingye, Ye Linhui, Liang Mengying, Huang Yue, Li Jiatian, Zhang Zhe, Deng Wentao, Ren Baiguang, Zhang Yingpei, Wang Li, Chen Xuejiao, Duan Yingxing, Han Zhe, Leng Yang, Li Hongxin, Hu Kongzhen, Huo Yongting, Lu Di
肿瘤
T细胞
肿瘤免疫
IL-10
T细胞
细胞生物学
PD-1
免疫/内分泌
