日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice.

将 RNAi 表达构建体通过 AAV 脑脊液内递送至非人灵长类动物和小鼠后,引起背根神经节毒性

Hawley Zachary C E, Pardo Ingrid D, Cao Shaolong, Zavodszky Maria I, Casey Fergal, Ferber Kyle, Luo Yi, Hana Sam, Chen Shukkwan K, Doherty Jessica, Costa Raquel, Cullen Patrick, Liu Yuqing, Carlile Thomas M, Chowdhury Twinkle, Doyle Benjamin, Clarner Pete, Mangaudis Kevin, Guilmette Edward, Bourque Shawn, Koske David, Nadella Murali V P, Trapa Patrick, Hawes Michael L, Raitcheva Denitza, Lo Shih-Ching

Viral-mediated knockdown of Atxn2 attenuates TDP-43 pathology and muscle dysfunction in the PFN1(C71G) ALS mouse model.

病毒介导的 Atxn2 敲低可减轻 PFN1(C71G) ALS 小鼠模型中的 TDP-43 病理和肌肉功能障碍

Hawley Zachary C E, Li Xueying, Bodnar Dora, Gu Yuanzheng, Luo Yi, Ferretti Daniel, Sheehy Adam, Driscoll Rachelle, Zavodszky Maria I, Cao Shaolong, Isaza Isabel, Jandreski Luke, Liu Yuqing, Carlile Thomas, Lo Shih-Ching, Grimard Anna, Bourque Shawn, Utturkar Aditya, Desmarais Samantha, Arnold H Moore, Huh Dann, Guilmette Edward, Kwon Deborah Y

Impact of Dietitian-Guided Individualized Nutrition (DGIN) on ICU Outcomes in Critically Ill Patients: A Retrospective Cohort Study in Taiwan

营养师指导的个体化营养(DGIN)对危重症患者ICU预后的影响:一项台湾回顾性队列研究

Lo, Shih-Ching; Lin, Hsing-Chun; Wang, Yu-Hsun; Chen, Ying-Ru; Yang, Shun-Fa

Engineered microRNA scaffolds for potent gene silencing in vivo.

工程化microRNA支架用于体内强效基因沉默

Militello Giuseppe, Greig Alyssa, Bi Chongfeng, Vasileva Ana, Zavodszky Maria I, Lo Shih-Ching, Guilmette Edward, Clarner Pete, Liu Bin, Bhat Guruharsha, Suh Junghae, Dow Lukas, Zuber Johannes, Fellmann Christof, Premsrirut Prem K

Inhibition of immune response reduces pathology in dorsal root ganglia and peripheral nerves in cynomolgus macaques following AAV gene therapy

抑制免疫反应可减轻食蟹猴在接受腺相关病毒(AAV)基因治疗后背根神经节和周围神经的病理变化。

Grubor, Branka; Henry, Kate L; Chan, Su Jing; Sheehan, Mark; Shah, Anumeha; Pellerin, Alex; Bai, Judy; Nadella, Prasad; Bommegowda, Santhosh; Cullen, Patrick; Tien, Eric; Chen, Vivian; van der Munnik, Nicholas P; White-Hunt, Stephanie; Plowey, Edward D; Hamann, Stefan; Guise, Amanda J; Xu, Shanqin; Kirkland, Melissa; Doherty, Jessica; Lyashenko, Eugenia; Bhat, Guruharsha; Glajch, Kelly; Lo, Shih-Ching; Gianni, Davide; Clarner, Pete; Gagnon, Jake; Chu, Jenhwa; Nambiar, Kalyani; Lulla, Mukesh; Zheng, Fengmei; Weldeab, Asmerom; Bartlett, Dan; Gutnick, Amos; Reynolds, Taylor; Zhu, Kan; Huh, Dann; Carlile, Thomas M; Fikes, James; Trapa, Patrick; Suh, Junghae; Morris, Dale; Burkly, Linda

Cis-regulatory elements driving motor neuron-selective viral payload expression within the mammalian spinal cord

驱动哺乳动物脊髓内运动神经元选择性病毒有效载荷表达的顺式调控元件

Nagy, M Aurel; Price, Spencer; Wang, Kristina; Gill, Stanley; Ren, Erika; Jayne, Lorna; Pajak, Victoria; Deighan, Sarah; Liu, Bin; Lu, Xiaodong; Diallo, Aissatou; Lo, Shih-Ching; Kleiman, Robin; Henderson, Christopher; Suh, Junghae; Griffith, Eric C; Greenberg, Michael E; Hrvatin, Sinisa

Development and Application of a Liquid Chromatography-Mass Spectrometry Method for Residual Iodixanol Quantification in AAV-Based Gene Therapy Product Development

开发和应用液相色谱-质谱法定量分析AAV基因治疗产品开发中的残留碘克沙醇

Pu, Yi; Katz, Russell; Chen, Yunqiu; Kostrubsky, Vic; Clarner, Pete; Lo, Shih-Ching; Sosic, Zoran; Yeung, Bernice

Nutritional support for successful weaning in patients undergoing prolonged mechanical ventilation

长期机械通气患者成功脱机所需的营养支持

Lo, Shih-Ching; Ma, Kevin Sheng-Kai; Li, Yen-Ru; Li, Zi-Yue; Lin, Cheng-Hung; Lin, Hsing-Chun; Yang, Shun-Fa

PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

PGAM5 将包含 Keap1 和 Nrf2 的三元复合物锚定到线粒体上。

Lo, Shih-Ching; Hannink, Mark

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

Keap1:Nrf2界面结构为Nrf2信号传导机制提供了深入见解

Lo, Shih-Ching; Li, Xuchu; Henzl, Michael T; Beamer, Lesa J; Hannink, Mark