日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer

基于重力的微过滤揭示了卵巢癌和结直肠癌中循环肿瘤细胞簇的意外流行率

Anne Meunier, Javier Alejandro Hernández-Castro, Nicholas Chahley, Laudine Communal, Sara Kheireddine, Newsha Koushki, Nadia Davoudvandi, Sara Al Habyan, Benjamin Péant, Anthoula Lazaris, Andy Ng, Teodor Veres, Luke McCaffrey, Diane Provencher, Peter Metrakos, Anne-Marie Mes-Masson, David Juncker3

LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis

LGN缺失导致纺锤体方向随机化,并加速PTEN缺陷型表皮的肿瘤发生。

Sophie Viala ,Charlotte Hadjadj ,Vandana Nathan ,Marie-Christine Guiot ,Luke McCaffrey ,Katie Cockburn ,Maxime Bouchard

Ezh2 promotes mammary tumor initiation through epigenetic regulation of the Wnt and mTORC1 signaling pathways

Ezh2通过表观遗传调控Wnt和mTORC1信号通路促进乳腺肿瘤发生

Linshan Liu, Bin Xiao, Alison Hirukawa, Harvey W Smith, Dongmei Zuo, Virginie Sanguin-Gendreau, Luke McCaffrey, Alice Jisoo Nam, William J Muller

Studying Cell Polarity Dynamics During Cancer Initiation Using Inducible 3D Organotypic Cultures

利用可诱导的 3D 器官型培养研究癌症发生过程中的细胞极性动力学

Rachel Catterall #, Reem Kurdieh #, Luke McCaffrey

3D chromatin remodeling potentiates transcriptional programs driving cell invasion

3D染色质重塑增强驱动细胞侵袭的转录程序

Benjamin Lebeau, Maïka Jangal, Tiejun Zhao, Cheng Kit Wong, Nolan Wong, Eduardo Cepeda Cañedo, Steven Hébert, Adriana Aguilar-Mahecha, Catherine Chabot, Marguerite Buchanan, Rachel Catterall, Luke McCaffrey, Geneviève Deblois, Claudia Kleinman, Morag Park, Mark Basik, Michael Witcher

CD13 orients the apical-basal polarity axis necessary for lumen formation

CD13 决定管腔形成所需的顶端-基底极性轴的方向

Li-Ting Wang ,Abira Rajah ,Claire M Brown ,Luke McCaffrey

Architectural control of metabolic plasticity in epithelial cancer cells

上皮癌细胞代谢可塑性的结构控制

Maia Al-Masri ,Karina Paliotti ,Raymond Tran ,Ruba Halaoui ,Virginie Lelarge ,Sudipa Chatterjee ,Li-Ting Wang ,Christopher Moraes ,Luke McCaffrey

A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding

GIV/Girdin 的长亚型含有 PDZ 结合模块,可调节定位和 G 蛋白结合

Jason Ear, Amer Ali Abd El-Hafeez, Suchismita Roy, Tony Ngo, Navin Rajapakse, Julie Choi, Soni Khandelwal, Majid Ghassemian, Luke McCaffrey, Irina Kufareva, Debashis Sahoo, Pradipta Ghosh

A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation

三维球体培养中的邻近蛋白质组学筛选可识别管腔形成的新调节剂

Li-Ting Wang, Marie-Ève Proulx, Anne D Kim, Virginie Lelarge, Luke McCaffrey

Girdin is a component of the lateral polarity protein network restricting cell dissemination

Girdin 是限制细胞传播的侧极性蛋白网络的组成部分

Cornélia Biehler, Li-Ting Wang, Myriam Sévigny, Alexandra Jetté, Clémence L Gamblin, Rachel Catterall, Elise Houssin, Luke McCaffrey, Patrick Laprise