日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetically engineered Streptomyces viridosporus ATCC 14672 strains for the discovery of novel moenomycins

利用基因工程改造的链霉菌ATCC 14672菌株发现新型莫能霉素

Ostash, Bohdan; Makitrynskyy, Roman; Fedchyshyn, Mariana; Luzhetskyy, Andriy; Walker, Suzanne; Fedorenko, Victor

Genome Mining-Driven Isolation of New Gromomycins and Insights into Their Mode of Action

基因组挖掘驱动的新型格罗莫霉素分离及其作用机制研究

Bratiichuk, Dmytro; Fries, Franziska; Stierhof, Marc; Morguet, Leon; Zapp, Josef; Müsken, Mathias; Rebets, Yuriy; Myronovskyi, Maksym; Müller, Rolf; Herrmann, Jennifer; Luzhetskyy, Andriy

Heterologous biosynthetic crosstalk with the native mansouramycin cluster in Streptomyces albus Del14 reveals unexpected metabolites

链霉菌(Streptomyces albus Del14)中与天然曼苏拉霉素簇的异源生物合成串扰揭示了意想不到的代谢物

Stierhof, Marc; Horbal, Liliya; Oberhäuser, Patrick; Palusczak, Anja; Cox, Peyton; Lopatniuk, Maria; Ruf, Christopher; Zapp, Josef; Luzhetskyy, Andriy

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

格罗莫霉素:一种前所未有的三萜类抗生素,由一种新型生物合成途径产生

Tistechok, Stepan; Bratiichuk, Dmytro; Sucipto, Hilda; Gummerlich, Nils; Stierhof, Marc; Gromyko, Oleksandr; Fries, Franziska; Fedorenko, Victor; Müller, Rolf; Zapp, Josef; Myronovskyi, Maksym; Luzhetskyy, Andriy

Identification and heterologous expression of an NRPS biosynthetic gene cluster responsible for the production of the pyrazinones Ichizinone A, B and C

鉴定并异源表达负责吡嗪酮类化合物 Ichizinone A、B 和 C 合成的非核糖体肽合成酶 (NRPS) 生物合成基因簇。

Oberhäuser, Patrick; Myronovskyi, Maksym; Stierhof, Marc; Gromyko, Oleksandr; Luzhetskyy, Andriy

Uncovering the genetic basis of antiviral polyketide limocrocin biosynthesis through heterologous expression

通过异源表达揭示抗病毒聚酮化合物limocrocin生物合成的遗传基础

Melnyk, Sofiia; Stierhof, Marc; Bratiichuk, Dmytro; Fries, Franziska; Müller, Rolf; Rebets, Yuriy; Luzhetskyy, Andriy; Ostash, Bohdan

Metabolic engineering of Streptomyces explomaris for increased production of the reverse antibiotic nybomycin

通过代谢工程改造链霉菌(Streptomyces explomaris)以提高反向抗生素尼博霉素的产量

Shu, Wei; Stegmüller, Julian; Rodriguez-Estevez, Marta; Rückert-Reed, Christian; Kalinowski, Jörn; Gromyko, Oleksandr; Rebets, Yuriy; Luzhetskyy, Andriy; Wittmann, Christoph

Description of Streptomyces explomaris sp. nov., isolated from the coastal soil rhizosphere of Juniperus excelsa and reclassification of Streptomyces libani as a later heterotypic synonym of Streptomyces nigrescens

对从杜松(Juniperus excelsa)沿海土壤根际分离得到的链霉菌(Streptomyces explomaris sp. nov.)进行了描述,并将黎巴嫩链霉菌(Streptomyces libani)重新分类为黑链霉菌(Streptomyces nigrescens)的异型同义词。

Shu, Wei; Rückert-Reed, Christian; Gromyko, Olexandr; Tistechok, Stepan; Kalinowski, Jörn; Luzhetskyy, Andriy; Wittmann, Christoph

An Improved Transformation-Associated Recombination Cloning Approach for Direct Capturing of Natural Product Biosynthetic Gene Clusters

一种改进的转化相关重组克隆方法用于直接捕获天然产物生物合成基因簇

Kurylenko, Olena; Palusczak, Anja; Luzhetskyy, Andriy; Rebets, Yuriy

Systems biology of industrial oxytetracycline production in Streptomyces rimosus: the secrets of a mutagenized hyperproducer

裂链霉菌工业土霉素生产的系统生物学:诱变高产菌的秘密

Selma Beganovic, Christian Rückert-Reed, Hilda Sucipto, Wei Shu, Lars Gläser, Thomas Patschkowski, Ben Struck, Jörn Kalinowski, Andriy Luzhetskyy, Christoph Wittmann