日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of diesel exhaust particles on infections with Mycobacterium bovis BCG in in vitro human macrophages and an in vivo Galleria mellonella model

柴油机尾气颗粒对体外人类巨噬细胞和体内蜡螟模型中牛分枝杆菌 BCG 感染的影响

Pablo Rodríguez-Fernández, Iris Romero-Andrada, Bárbara Molina-Moya, Irene Latorre, Alícia Lacoma, Cristina Prat-Aymerich, Lydia Tabernero, José Domínguez

MptpB Inhibitor Improves the Action of Antibiotics against Mycobacterium tuberculosis and Nontuberculous Mycobacterium avium Infections

MptpB 抑制剂可增强抗生素对结核分枝杆菌和非结核性鸟分枝杆菌感染的作用

Pablo Rodríguez-Fernández, Laure Botella, Jennifer S Cavet, Jose Domínguez, Maximiliano G Gutierrez, Colin J Suckling, Fraser J Scott, Lydia Tabernero

Discovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis

发现 SapM 的非竞争性抑制剂,可损害结核分枝杆菌的细胞内存活

Paulina Fernández-Soto, Joshua Casulli, Danilo Solano-Castro, Pablo Rodríguez-Fernández, Thomas A Jowitt, Mark A Travis, Jennifer S Cavet, Lydia Tabernero

Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence

针对真菌病原体中的蛋氨酸合酶导致代谢失衡,影响细胞能量、生长和毒力

Jennifer Scott, Monica Sueiro-Olivares, Benjamin P Thornton, Rebecca A Owens, Howbeer Muhamadali, Rachael Fortune-Grant, Darren Thomson, Riba Thomas, Katherine Hollywood, Sean Doyle, Royston Goodacre, Lydia Tabernero, Elaine Bignell, Jorge Amich

Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs

结核分枝杆菌SapM的催化和抑制机制及其对新型抗毒药物开发的意义

Paulina Fernandez-Soto, Alexander J E Bruce, Alistair J Fielding, Jennifer S Cavet, Lydia Tabernero

Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo

基于结构的设计 MptpB 抑制剂可降低体内耐多药结核分枝杆菌的存活率和感染负担

Clare F Vickers, Ana P G Silva, Ajanta Chakraborty, Paulina Fernandez, Natalia Kurepina, Charis Saville, Yandi Naranjo, Miquel Pons, Laura S Schnettger, Maximiliano G Gutierrez, Steven Park, Barry N Kreiswith, David S Perlin, Eric J Thomas, Jennifer S Cavet, Lydia Tabernero

Identification and functional analysis of a novel oculocerebrorenal syndrome of Lowe (OCRL) gene variant in two pedigrees with varying phenotypes including isolated congenital cataract

在两个具有不同表型(包括孤立性先天性白内障)的家系中对新型 Lowe 眼脑肾综合征 (OCRL) 基因变异进行鉴定和功能分析

Ahmed K Shalaby, Peter Emery-Billcliff, Diana Baralle, Tabib Dabir, Shahiba Begum, Sarah Waller, Lydia Tabernero, Martin Lowe, James Self

Identification and functional analysis of a novel oculocerebrorenal syndrome of Lowe (OCRL) gene variant in two pedigrees with varying phenotypes including isolated congenital cataract

对两个具有不同表型(包括孤立性先天性白内障)的家系中一种新的Lowe眼脑肾综合征(OCRL)基因变异进行鉴定和功能分析。

Ahmed K Shalaby,Peter Emery-Billcliff,Diana Baralle,Tabib Dabir,Shahiba Begum,Sarah Waller,Lydia Tabernero,Martin Lowe,James Self

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

TGFβ信号调节因子SARA/Endofin与HD-PTP特异性相互作用的结构基础

Deepankar Gahloth,Colin Levy,Louise Walker,Lydia Wunderley,A Paul Mould,Sandra Taylor,Philip Woodman,Lydia Tabernero

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

TGFβ 信号调节剂 SARA/Endofin 与 HD-PTP 特异性相互作用的结构基础

Deepankar Gahloth, Colin Levy, Louise Walker, Lydia Wunderley, A Paul Mould, Sandra Taylor, Philip Woodman, Lydia Tabernero