MacFawn相关文献与解析，生知库 | 链接生命科学的每一步

Garcia Geyon L, Orellana Taylor, Gorecki Grace, Frisbie Leonard, Baruwal Roja, Suresh Swathi, Goldfeld Ester, Beddows Ian, MacFawn Ian P, Britt Ananya K, Hale Macy M, Elhaw Amal Taher, Isett Brian R, Hempel Nadine, Bao Riyue, Shen Hui, Buckanovich Ronald J, Finkel Toren, Drapkin Ronny, Soong T Rinda, Bruno Tullia C, Atiya Huda I, Coffman Lan G

细胞生物学

细胞衰老

发表日期：2025

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Dysfunctional CD11c(-)CD21(-) extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer

功能异常的CD11c(-)CD21(-)滤泡外记忆B细胞在癌症患者的外周血和肿瘤组织中富集。

期刊:Science Translational Medicine

影响因子:14.6

doi:10.1126/scitranslmed.adh1315

Ruffin, Ayana T; Casey, Allison N; Kunning, Sheryl R; MacFawn, Ian P; Liu, Zhentao; Arora, Charu; Rohatgi, Anjali; Kemp, Felicia; Lampenfeld, Caleb; Somasundaram, Ashwin; Rappocciolo, Giovanna; Kirkwood, John M; Duvvuri, Umamaheswar; Seethala, Raja; Bao, Riyue; Huang, Yufei; Cillo, Anthony R; Ferris, Robert L; Bruno, Tullia C

Past failures and new horizons: the nuances of tertiary lymphoid structures in high-grade serous ovarian cancer may contribute to immunotherapy effectiveness

过去的失败与新的前景：高级别浆液性卵巢癌中三级淋巴结构的细微差别可能有助于提高免疫疗法的疗效。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2025-011670

Rashid, Rufiaat; Coffman, Lan; Bruno, Tullia C; MacFawn, Ian

Prognostic Value of Lymphoid Infiltration and Aggregation in Cervical Cancer.

淋巴浸润和聚集在宫颈癌中的预后价值。

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers18010129

Gorecki Grace, Hale Macy, Taylor Sarah, Garcia Geyon, MacFawn Ian P, Soong T Rinda, Bruno Tullia C, Coffman Lan

TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

放疗期间抑制TGFβ可增强免疫细胞浸润并减少尤文氏肉瘤的转移

期刊:Cancer Research Communications

影响因子:2

doi:10.1158/2767-9764.CRC-24-0346

Jessica D Daley ，Elina Mukherjee ，David Ferraro ，A Carolina Tufino ，Nathanael Bailey ，Shanthi Bhaskar ，Nivitha Periyapatna ，Ian MacFawn ，Sean Hartwick ，Sheryl Kunning ，Cynthia Hinck ，Tullia C Bruno ，Adam C Olson ，Linda M McAllister-Lucas ，Andrew P Hinck ，Kristine Cooper ，Riyue Bao ，Anthony R Cillo ，Kelly M Bailey

The activity of tertiary lymphoid structures in high grade serous ovarian cancer is governed by site, stroma, and cellular interactions

高级别浆液性卵巢癌中三级淋巴结构的活性受肿瘤部位、间质和细胞相互作用的调控。

期刊:Cancer Cell

影响因子:48.8

doi:10.1016/j.ccell.2024.09.007

Ian P MacFawn ，Grant Magnon ，Grace Gorecki ，Sheryl Kunning ，Rufiaat Rashid ，Medard Ernest Kaiza ，Huda Atiya ，Ayana T Ruffin ，Sarah Taylor ，T Rinda Soong ，Riyue Bao ，Lan G Coffman ，Tullia C Bruno

Grainyhead-like-2, an epithelial master programmer, promotes interferon induction and suppresses breast cancer recurrence.

Grainyhead-like-2 是一种上皮细胞主控因子，可促进干扰素诱导并抑制乳腺癌复发

期刊:Molecular Immunology

影响因子:3

doi:10.1016/j.molimm.2024.04.012

MacFawn Ian, Farris Joshua, Pifer Phillip, Margaryan Naira V, Akhter Halima, Wang Lei, Dziadowicz Sebastian, Denvir James, Hu Gangqing, Frisch Steven M

Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation

免疫功能健全的小鼠尤文氏肉瘤模型揭示了TGFβ抑制在放射治疗期间增强尤文氏肿瘤免疫浸润中的作用

期刊:

影响因子:

doi:10.1101/2024.05.07.592974

Daley, Jessica D; Mukherjee, Elina; Tufino, A Carolina; Bailey, Nathanael; Bhaskar, Shanthi; Periyapatna, Nivitha; MacFawn, Ian; Kunning, Sheryl; Hinck, Cynthia; Bruno, Tullia; Olson, Adam C; McAllister-Lucas, Linda M; Hinck, Andrew P; Cooper, Kristine; Bao, Riyue; Cillo, Anthony R; Bailey, Kelly M

Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer

型树突状细胞控制癌症中三级淋巴结构的形成、维持和功能

期刊:

影响因子:

doi:10.1101/2024.12.27.628014

Raphaël Mattiuz, Jesse Boumelha, Pauline Hamon, Jessica Le Berichel, Abishek Vaidya, Brian Y Soong, Laszlo Halasz, Emir Radkevich, Hye Mi Kim, Matthew D Park, Romain Donne, Leanna Troncoso, Darwin D'Souza, Medard Ernest Kaiza, Ian P MacFawn, Meriem Belabed, Guillaume Mestrallet, Etienne Humblin, Rap

Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes

肿瘤中淋巴结构相关细胞因子/趋化因子基因转录本的表达以及血清中相关蛋白的表达可预测黑色素瘤患者的预后。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2023.1171978

Karapetyan, Lilit; AbuShukair, Hassan M; Li, Aofei; Knight, Andrew; Al Bzour, Ayah Nedal; MacFawn, Ian P; Thompson, Zachary J; Chen, Ann; Yang, Xi; Dadey, Rebekah; Karunamurthy, Arivarasan; De Stefano, Danielle Vargas; Sander, Cindy; Kunning, Sheryl R; Najjar, Yana G; Davar, Diwakar; Luke, Jason J; Gooding, William; Bruno, Tullia C; Kirkwood, John M; Storkus, Walter J

Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation.

衰老和携带 BRCA 突变的基质细胞驱动上皮细胞转化

Dysfunctional CD11c(-)CD21(-) extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer

功能异常的CD11c(-)CD21(-)滤泡外记忆B细胞在癌症患者的外周血和肿瘤组织中富集。

Past failures and new horizons: the nuances of tertiary lymphoid structures in high-grade serous ovarian cancer may contribute to immunotherapy effectiveness

过去的失败与新的前景：高级别浆液性卵巢癌中三级淋巴结构的细微差别可能有助于提高免疫疗法的疗效。

Prognostic Value of Lymphoid Infiltration and Aggregation in Cervical Cancer.

淋巴浸润和聚集在宫颈癌中的预后价值。

TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

放疗期间抑制TGFβ可增强免疫细胞浸润并减少尤文氏肉瘤的转移

The activity of tertiary lymphoid structures in high grade serous ovarian cancer is governed by site, stroma, and cellular interactions

高级别浆液性卵巢癌中三级淋巴结构的活性受肿瘤部位、间质和细胞相互作用的调控。

Grainyhead-like-2, an epithelial master programmer, promotes interferon induction and suppresses breast cancer recurrence.

Grainyhead-like-2 是一种上皮细胞主控因子，可促进干扰素诱导并抑制乳腺癌复发

Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation

免疫功能健全的小鼠尤文氏肉瘤模型揭示了TGFβ抑制在放射治疗期间增强尤文氏肿瘤免疫浸润中的作用

Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer

型树突状细胞控制癌症中三级淋巴结构的形成、维持和功能

Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes

肿瘤中淋巴结构相关细胞因子/趋化因子基因转录本的表达以及血清中相关蛋白的表达可预测黑色素瘤患者的预后。