日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

LSD1 Inhibition Induces MHC-I and Dendritic Cell Activation to Promote Antitumor Immunity in Head and Neck Squamous Cell Carcinoma

LSD1抑制诱导MHC-I和树突状细胞活化,从而促进头颈部鳞状细胞癌的抗肿瘤免疫。

Amit Kumar Chakraborty,Lina Kroehling,Rajnikant Dilip Raut,Chumki Choudhury,Maria A Kukuruzinska,J Silvio Gutkind,Xaralabos Varelas,Bikash Sahay,Stefano Monti,Manish V Bais

Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression

赖氨酸特异性去甲基化酶1通过CDK7磷酸化调控关键的OSCC癌前病变诱导因子STAT3,从而在肿瘤发生发展和免疫抑制过程中发挥作用。

Amit Kumar Chakraborty # ,Rajnikant Dilip Raut # ,Kisa Iqbal ,Chumki Choudhury ,Thabet Alhousami ,Sami Chogle ,Alexa S Acosta ,Lana Fagman ,Kelly Deabold ,Marilia Takada ,Bikash Sahay ,Vikas Kumar ,Manish V Bais

A multi-tissue human knee single-cell atlas identifies that osteoarthritis reduces regenerative tissue stem cells while increasing inflammatory pain macrophages

一项针对人类膝关节多组织单细胞图谱的研究发现,骨关节炎会减少再生组织干细胞,同时增加炎症性疼痛巨噬细胞。

Raut, Rajnikant Dilip; Chakraborty, Amit Kumar; Neogi, Tuhina; Albro, Michael; Snyder, Brian; Schaer, Thomas P; Zhang, Chao; Grinstaff, Mark W; Bais, Manish V

Comprehensive In Vitro Safety Assessment of Acorus calamus Rhizome Oil Using OECD-Compliant New Approach Methods: Classification as a GHS Category 1B Sensitiser and Category 2 Irritant

采用符合经合组织标准的新型方法对菖蒲根茎油进行全面的体外安全性评估:将其归类为全球化学品统一分类和标签制度(GHS)1B类致敏物和2类刺激物

Desai, Karishma R; Ranade, Jay R; Nagane, Rajendra M; Patel, Manish V; Deshpande, Abhay D; Roper, Clive S; Kantli, Gireesh Babu

Integrative analysis identifies FBXO5 as a critical mediator of CRPC progression and bone metastatic potential.

综合分析表明,FBXO5 是 CRPC 进展和骨转移潜能的关键介质

Raut Rajnikant, Srivastava Devesh, Chakraborty Amit Kumar, Bais Manish V, Mishra Parul, Misra Ashish

Clinical data investigation identifies MARK3 as an oncogenic driver in castration-resistant prostate cancer

临床数据研究发现 MARK3 是去势抵抗性前列腺癌中的致癌驱动因子。

Raut, Rajnikant; Srivastava, Devesh; Nayak, Vinayak; Saini, Taruna; Gupta, Parth; Chakraborty, Amit Kumar; Choudhury, Chumki; Bais, Manish V; Mishra, Parul; Misra, Ashish

A Humanized Mouse Model of Oral Squamous Cell Carcinoma for Investigating Resistance to Anti-PD1 Immunotherapy

利用人源化小鼠口腔鳞状细胞癌模型研究抗PD-1免疫疗法的耐药性

Chakraborty, Amit Kumar; Choudhury, Chumki; Raut, Rajnikant Dilip; Bais, Manish V

LOXL2 Deletion Triggers TMJ Osteoarthritis While Overexpression Protects Against NF-κβ-Induced Chondrocyte Apoptosis

LOXL2 缺失会诱发颞下颌关节骨关节炎,而过表达则可抵抗 NF-κβ 诱导的软骨细胞凋亡

Raut, Rajnikant Dilip; Choudhury, Chumki; Ali, Faiza; Chakraborty, Amit Kumar; Ahmed, Mohammed Moeeduddin; Del Valle-Ponce De Leon, Cheyleann; Modh, Harshal V; Mehra, Pushkar; Fan, Yuwei; Almarza, Alejandro; Bais, Manish V

Dietary Serine Restriction Impacts H3K27 and H3K4 Methyl Epigenomes to Impede Head and Neck Cancer Cell Plasticity and Tumor Growth

饮食中丝氨酸限制会影响H3K27和H3K4甲基化表观基因组,从而抑制头颈癌细胞的可塑性和肿瘤生长。

Jankowski, Stacy A; Kroehling, Lina; Bais, Manish V; Hardy, Nina C; Varelas, Xaralabos; Monti, Stefano; Kukuruzinska, Maria A

An architecturally rational hemostat for rapid stopping of massive bleeding on anticoagulation therapy

一种结构合理的止血装置,用于快速止住抗凝治疗期间的大出血

Lee, Vivian K; Lee, Taewoo; Ghosh, Amrit; Saha, Tanmoy; Bais, Manish V; Bharani, Kala Kumar; Chag, Milan; Parikh, Keyur; Bhatt, Parloop; Namgung, Bumseok; Venkataramanan, Geethapriya; Agrawal, Animesh; Sonaje, Kiran; Mavely, Leo; Sengupta, Shiladitya; Mashelkar, Raghunath Anant; Jang, Hae Lin