日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Detection of developmental toxicity of the anti-COVID-19 drug molnupiravir using gastruloid-based in vitro assays

利用基于类胃胚的体外试验检测抗COVID-19药物莫努匹拉韦的发育毒性

Huntsman, Margaret Carrell; Marikawa, Yusuke

Embryotoxicity analysis of anti-arrhythmia drugs amiodarone, dronedarone, and their metabolites using 3D gastruloid models

利用三维类原肠胚模型分析抗心律失常药物胺碘酮、决奈达隆及其代谢物的胚胎毒性

Kurashima, Courtney Kehaulani; Marikawa, Yusuke

Regulation of trophectoderm morphogenesis by small GTPase RHOA through HIPPO signaling-dependent and -independent mechanisms in mouse preimplantation development.

在小鼠胚胎植入前发育过程中,小 GTP 酶 RHOA 通过 HIPPO 信号依赖性和非依赖性机制调控滋养外胚层形态发生

Marikawa Yusuke, Alarcon Vernadeth B

Validation of a mouse 3D gastruloid-based embryotoxicity assay in reference to the ICH S5(R3) guideline chemical exposure list.

参照 ICH S5(R3) 指南化学品暴露清单,验证基于小鼠 3D 原肠胚的胚胎毒性试验

Huntsman Margaret Carrell, Kurashima Courtney Kehaulani, Marikawa Yusuke

Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signaling

滋养外胚层形成:RHO、ROCK、细胞极性和HIPPO信号通路对形态发生和基因表达的调控

Alarcon, Vernadeth B; Marikawa, Yusuke

Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration

祖先干细胞重编程基因在半索动物再生中活跃

Humphreys, Tom; Weiser, Keith; Arimoto, Asuka; Sasaki, Akane; Uenishi, Gene; Fujimoto, Brent; Kawashima, Takeshi; Taparra, Kekoa; Molnar, Janos; Satoh, Noriyuki; Marikawa, Yusuke; Tagawa, Kuni

Gastruloids: Pluripotent stem cell models of mammalian gastrulation and embryo engineering

类原肠胚:哺乳动物原肠形成和胚胎工程的多能干细胞模型

Arias, Alfonso Martinez; Marikawa, Yusuke; Moris, Naomi

ROCK and RHO Playlist for Preimplantation Development: Streaming to HIPPO Pathway and Apicobasal Polarity in the First Cell Differentiation

ROCK 和 RHO 细胞在植入前发育中的作用:HIPPO 通路的激活和首细胞分化中的顶底极性

Alarcon, Vernadeth B; Marikawa, Yusuke

Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos

血管生成素的极性依赖性分布决定了植入前胚胎中 Hippo 信号的定位

Hirate, Yoshikazu; Hirahara, Shino; Inoue, Ken-Ichi; Suzuki, Atsushi; Alarcon, Vernadeth B; Akimoto, Kazunori; Hirai, Takaaki; Hara, Takeshi; Adachi, Makoto; Chida, Kazuhiro; Ohno, Shigeo; Marikawa, Yusuke; Nakao, Kazuki; Shimono, Akihiko; Sasaki, Hiroshi

Creation of trophectoderm, the first epithelium, in mouse preimplantation development

小鼠胚胎植入前发育过程中滋养外胚层(第一个上皮组织)的形成

Marikawa, Yusuke; Alarcon, Vernadeth B