日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

l-2-Hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression

2-羟基戊二酸通过表观遗传激活MYC表达来损害神经元分化。

Gu, Wen; Wang, Xun; Solmonson, Ashley; Cai, Ling; Xiao, Yi; Tasdogan, Alpaslan; Franklin, Jordan; Zhang, Yuannyu; Zhang, Hua; Westfall, Aundrea K; Rowe, Ashley; Trivedi, Hetali; Faubert, Brandon; Wu, Zheng; Sudderth, Jessica; Zacharias, Lauren G; Afroze, Bushra; Bezprozvanny, Ilya; Sudarshan, Sunil; Cai, Feng; McBrayer, Samuel K; Mathews, Thomas P; DeBerardinis, Ralph J

A recurrent ACAA2 variant causes a dominant syndrome of lipodystrophy, lipomatosis, infantile steatohepatitis, and hypoglycemia

ACAA2基因的一种复发性变异会导致一种显性遗传综合征,其特征为脂肪营养不良、脂肪瘤病、婴儿脂肪性肝炎和低血糖症。

Simha, Vinaya; LoPiccolo, Mary Kate; Platt, Anna; Brown, Rebecca J; Johnson, Xandria; Carere, Deanna Alexis; Donnelly, Colleen; Snyder, Matthew T; Xing, Chao; Mathews, Thomas P; Gopal, Purva; Ward, Stephen C; Tomchick, Diana R; Agarwal, Anil K; DeBerardinis, Ralph J; Garg, Abhimanyu

Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment

在类人血浆介质中进行稳定同位素示踪揭示了胶质母细胞瘤微环境的代谢和免疫调节

Savani, Milan R; El Shami, Mohamad; Miki, Kenji; Gattie, Lauren C; Smith, Bailey C; Hicks, William H; Weiss, Jacob O; Oken, Skyler S; Katta, Lavanya N; Shipman, Tracey; Ghoche, Maged T; Zacharias, Lauren G; Martin-Sandoval, Misty S; Montgomery, Eric Y; Xiao, Yi; Shi, Diana D; Rich, Jeremy N; Richardson, Timothy E; Zinn, Pascal O; Lega, Bradley C; Mathews, Thomas P; DeBerardinis, Ralph J; Abdullah, Kalil G; McBrayer, Samuel K

A Stable Isotope Tracing Primer for the Mass Spectrometrist

质谱分析稳定同位素示踪入门

Solmonson, Ashley; Faubert, Brandon; Mathews, Thomas P

NAD(+) sensing by PARP7 regulates the C/EBPβ-dependent transcription program during adipogenesis.

PARP7 对 NAD(+) 的感知调节脂肪生成过程中 C/EBPβ 依赖的转录程序。

Stokes MiKayla S, Kim Yoon Jung, Kim Yonghyeon, Koul Sneh, Chiu Shu-Ping, Liu Chenqian, Dasovich Morgan, Zuniga Josue, Nandu Tulip, Huang Dan, Mathews Thomas P, Solmonson Ashley, Camacho Cristel V, Kraus W Lee

SREBP governs a triglyceride:glycogen metabolic switch in Drosophila

SREBP调控果蝇体内的甘油三酯:糖原代谢转换

Ugrankar-Banerjee, Rupali; Tran, Son; Srivastava, Sonakshi; Bowerman, Jade; Paul, Blessy; Zacharias, Lauren G; Mathews, Thomas P; DeBerardinis, Ralph J; Henne, W Mike

Leptin Receptor (+) cells create a perisinusoidal niche for thrombopoiesis in the bone marrow by synthesizing CXCL14

瘦素受体(+)细胞通过合成CXCL14,在骨髓中形成血小板生成所需的窦周微环境。

Xue, Yuanyuan; Merchant, Salma; Reyes, Amanda; Luo, Maowu; Zhang, Ruixuan; Tippetts, Trevor; Grabowski, Gerik; Ngo, Tai; Zhang, Yanan; Shang, Zhiguo; Jiang, Nisi; Jeffery, Elise; Li, Yafeng; Wei, Tao; Gu, Wen; Du, Liming; DeBerardinis, Ralph J; Dean, Kevin M; Mathews, Thomas P; Lucas, Daniel; Zhao, Zhiyu; Morrison, Sean J

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT

NUDT5 通过与 PPAT 相互作用来调节嘌呤代谢和硫嘌呤敏感性。

Wu, Zheng; Nguyen, Phong T; Sondhi, Varun; Yao, Run-Wen; Lu, Zhifang; Dai, Tao; Chiang, Jui-Chung; Cai, Feng; Williams, Imani M; Blatt, Eliot B; Shang, Zengfu; Cai, Ling; Zhang, Jing; Moore, Mya D; Alshamleh, Islam; Li, Xiangyi; Ogu, Tamaratare; Zacharias, Lauren G; Winston, Rainah; Patricio, Joao S; Johnson, Xandria; Chen, Wei-Min; Cong, Qian; Mathews, Thomas P; Zhang, Yuanyuan; Zhang, Limei; DeBerardinis, Ralph J

High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non-Small Cell Lung Cancer in Patients.

高葡萄糖对三羧酸循环的贡献是侵袭性非小细胞肺癌患者的一个特征。

Cai Ling, Hammond Nia G, Tasdogan Alpaslan, Alsamraae Massar, Yang Chendong, Cameron Robert B, Quan Peiran, Solmonson Ashley, Gu Wen, Pachnis Panayotis, Kaur Mayher, Chang Brianna K, Zhou Qin, Hensley Christopher T, Do Quyen N, Martins Nascentes Melo Luiza, Ubellacker Jessalyn M, Kaushik Akash, Clare Maia G, Alcazar Isabel N, Kurylowicz Katarzyna, Marcuccilli Joseph D, Allies Gabriele, Kutritz Andrea, Klode Joachim, Ramesh Vijayashree, Rogers Thomas J, Rao Aparna D, Crentsil Hannah E, Li Hong, Brister Fang, McDaniel Phyllis, Xu Xiaohong, Evers Bret M, Zacharias Lauren G, Sudderth Jessica, Xu Jian, Mathews Thomas P, Oliver Dwight, Minna John D, Waters John, Morrison Sean J, Kernstine Kemp H, Faubert Brandon, DeBerardinis Ralph J

Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors

抗坏血酸缺乏会增加造血干细胞和多能祖细胞的静止状态和自我更新能力。

Comazzetto, Stefano; Cassidy, Daniel L; DeVilbiss, Andrew W; Jeffery, Elise C; Ottesen, Bethany R; Reyes, Amanda R; Paul, Animesh; Bansal, Suraj; Xie, Stephanie Z; Muh, Sarah; Mathews, Thomas P; Chen, Brandon; Zhao, Zhiyu; Morrison, Sean J