日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years

对接受filgotinib治疗的中度至重度活动性类风湿关节炎患者进行为期1.6年的综合安全性分析

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2021-221051
Winthrop, Kevin L; Tanaka, Yoshiya; Takeuchi, Tsutomu; Kivitz, Alan; Matzkies, Franziska; Genovese, Mark C; Jiang, Deyuan; Chen, Kun; Bartok, Beatrix; Jahreis, Angelika; Besuyen, Robin; Burmester, Gerd R; Gottenberg, Jacques-Eric
关节炎
发表日期：2022
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Semi-Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA

半机制药代动力学/药效学建模和不可逆BTK抑制模拟，以支持类风湿关节炎患者Tirabrutinib的剂量选择

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.2439
Meng, Amy; Humeniuk, Rita; Jürgensmeier, Juliane M; Hsueh, Chia-Hsiang; Matzkies, Franziska; Grant, Ethan; Truong, Hoa; Billin, Andrew N; Yu, Helen; Feng, Joy; Kwan, Ellen; Tarnowski, Thomas; Nelson, Cara H
BTK
关节炎
发表日期：2022
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Filgotinib or lanraplenib in moderate to severe cutaneous lupus erythematosus: a phase 2, randomized, double-blind, placebo-controlled study

菲戈替尼或拉拉普利尼治疗中重度皮肤红斑狼疮：一项 2 期随机、双盲、安慰剂对照研究

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/keab685
Werth, Victoria P; Fleischmann, Roy; Robern, Michael; Touma, Zahi; Tiamiyu, Iyabode; Gurtovaya, Oksana; Pechonkina, Alena; Mozaffarian, Afsaneh; Downie, Bryan; Matzkies, Franziska; Wallace, Daniel
红斑狼疮
免疫/内分泌
发表日期：2022
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Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial

在既往未接受过甲氨蝶呤治疗或接受过甲氨蝶呤治疗的活动性类风湿关节炎患者中，菲戈替尼联合甲氨蝶呤或单药治疗与甲氨蝶呤单药治疗的疗效比较：FINCH 3 期随机对照试验

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2020-219213
Westhovens, René; Rigby, William F C; van der Heijde, Désirée; Ching, Daniel W T; Stohl, William; Kay, Jonathan; Chopra, Arvind; Bartok, Beatrix; Matzkies, Franziska; Yin, Zhaoyu; Guo, Ying; Tasset, Chantal; Sundy, John S; Jahreis, Angelika; Mozaffarian, Neelufar; Messina, Osvaldo Daniel; Landewé, Robert Bm; Atsumi, Tatsuya; Burmester, Gerd R
FINC
关节炎
发表日期：2021
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Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial

在对甲氨蝶呤反应不足的类风湿性关节炎患者中，菲戈替尼与安慰剂或阿达木单抗的疗效比较：一项 III 期随机临床试验

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2020-219214
Combe, Bernard; Kivitz, Alan; Tanaka, Yoshiya; van der Heijde, Désirée; Simon, J Abraham; Baraf, Herbert S B; Kumar, Uma; Matzkies, Franziska; Bartok, Beatrix; Ye, Lei; Guo, Ying; Tasset, Chantal; Sundy, John S; Jahreis, Angelika; Genovese, Mark C; Mozaffarian, Neelufar; Landewé, Robert B M; Bae, Sang-Cheol; Keystone, Edward C; Nash, Peter
关节炎
发表日期：2021
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Characterization of the mechanism of action of lanraplenib, a novel spleen tyrosine kinase inhibitor, in models of lupus nephritis

新型脾酪氨酸激酶抑制剂兰拉普利尼在狼疮性肾炎模型中的作用机制表征

期刊:BMC Rheumatology
影响因子:2.1
doi:10.1186/s41927-021-00178-3
Christopher W Pohlmeyer, Ching Shang, Pei Han, Zhi-Hua Cui, Randall M Jones, Astrid S Clarke, Bernard P Murray, David A Lopez, David W Newstrom, M David Inzunza, Franziska G Matzkies, Kevin S Currie, Julie A Di Paolo
免疫
肾炎
发表日期：2021
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Lack of sensitivity of an IVD/CE-labelled kit targeting the S gene for detection of SARS-CoV-2

针对SARS-CoV-2 S基因的体外诊断/CE认证试剂盒灵敏度不足

期刊:Clinical Microbiology and Infection
影响因子:8.5
doi:10.1016/j.cmi.2020.06.036
Matzkies, L-M; Leitner, E; Stelzl, E; Assig, K; Bozic, M; Siebenhofer, D; Mustafa, M E; Steinmetz, I; Kessler, H H
SARS-CoV-2
发表日期：2020
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Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy: The FINCH 2 Randomized Clinical Trial

菲戈替尼与安慰剂对难治性中重度类风湿关节炎患者临床反应的影响：FINCH 2 随机临床试验

期刊:Journal of the American Medical Association
影响因子:55
doi:10.1001/jama.2019.9055
Genovese, Mark C; Kalunian, Kenneth; Gottenberg, Jacques-Eric; Mozaffarian, Neelufar; Bartok, Beatrix; Matzkies, Franziska; Gao, Jie; Guo, Ying; Tasset, Chantal; Sundy, John S; de Vlam, Kurt; Walker, David; Takeuchi, Tsutomu
FINC
关节炎
发表日期：2019
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Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor

中链脂肪酸通过心脏嗅觉受体调节心肌功能

期刊:Basic Research in Cardiology
影响因子:7.5
doi:10.1007/s00395-017-0600-y
Nikolina Jovancevic, A Dendorfer, M Matzkies, M Kovarova, J C Heckmann, M Osterloh, M Boehm, L Weber, F Nguemo, J Semmler, J Hescheler, H Milting, E Schleicher, L Gelis, H Hatt
信号转导
发表日期：2017
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Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study

强直性脊柱炎患者肠道炎症标志物：一项初步研究

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/ar4106
Matzkies, Franziska G; Targan, Stephan R; Berel, Dror; Landers, Carol J; Reveille, John D; McGovern, Dermot P B; Weisman, Michael H
炎症
肠炎
炎症/感染
强直性脊柱炎
免疫/内分泌
发表日期：2012
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