日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Differential effects of voluntary exercise and Totum-448, a plant-based formulation, in a hamster model of MASLD

在仓鼠MASLD模型中，自愿运动和植物制剂Totum-448的不同作用

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-43177-5
Chavanelle, Vivien; Ennequin, Gaël; Ripoche, Doriane; Otero, Yolanda F; Joubioux, Florian Le; Maugard, Thierry; Hervieu, Valérie; Peltier, Sébastien; Sirvent, Pascal
发表日期：2026
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TOTUM-854 Human Circulating Bioactives Preserve Endothelial Cell Function.

TOTUM-854 人类循环生物活性物质可维持内皮细胞功能

期刊:Nutrients
影响因子:5
doi:10.3390/nu17081331
Wauquier Fabien, Ripoche Doriane, Boutin-Wittrant Line, Otero Yolanda F, Krisa Stéphanie, Valls Josep, Maura Mahéva, Le Joubioux Florian, Maugard Thierry, Bolea Gaëtan, Meyer Grégory, Reboul Cyril, Roux Véronique, Macian Nicolas, Pickering Gisèle, Pereira Bruno, Bargetto Maxime, Sapone Véronique, Cazaubiel Murielle, Peltier Sébastien, Sirvent Pascal, Wittrant Yohann
细胞生物学
Human
发表日期：2025
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Totum-448 Improves MASLD and Modulates Microbiota in Hamsters: Dose-Response Study and Effects of Supplementation Cessation.

Totum-448 改善 MASLD 并调节仓鼠的微生物群：剂量反应研究和停止补充的影响

期刊:Food Science & Nutrition
影响因子:3.8
doi:10.1002/fsn3.70904
Chavanelle Vivien, Vallier Marie, Otero Yolanda F, Ripoche Doriane, Le Joubioux Florian, Maugard Thierry, Ennequin Gaël, Hervieu Valérie, Peltier Sébastien, Sirvent Pascal
微生物学
发表日期：2025
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Exopolysaccharide from marine microalgae belonging to the Glossomastix genus: fragile gel behavior and suspension stability

来自海洋微藻（属于舌鞭藻属）的胞外多糖：易碎凝胶行为和悬浮稳定性

期刊:Bioengineered
影响因子:4.2
doi:10.1080/21655979.2023.2296257
Dulong, Virginie; Rihouey, Christophe; Gaignard, Clément; Bridiau, Nicolas; Gourvil, Priscilla; Laroche, Céline; Pierre, Guillaume; Varacavoudin, Tony; Probert, Ian; Maugard, Thierry; Michaud, Philippe; Picton, Luc; Le Cerf, Didier
发表日期：2024
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Inhibitory Potential of α-Amylase, α-Glucosidase, and Pancreatic Lipase by a Formulation of Five Plant Extracts: TOTUM-63

五种植物提取物制剂对α-淀粉酶、α-葡萄糖苷酶和胰脂肪酶的抑制潜力：TOTUM-63

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24043652
Haguet, Quentin; Le Joubioux, Florian; Chavanelle, Vivien; Groult, Hugo; Schoonjans, Nathan; Langhi, Cédric; Michaux, Arnaud; Otero, Yolanda F; Boisseau, Nathalie; Peltier, Sébastien L; Sirvent, Pascal; Maugard, Thierry
发表日期：2023
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Role of some structural features in EPS from microalgae stimulating collagen production by human dermal fibroblasts

微藻胞外多糖中某些结构特征在刺激人真皮成纤维细胞产生胶原蛋白中的作用

期刊:Bioengineered
影响因子:4.2
doi:10.1080/21655979.2023.2254027
Toucheteau, Claire; Deffains, Valentine; Gaignard, Clément; Rihouey, Christophe; Laroche, Céline; Pierre, Guillaume; Lépine, Olivier; Probert, Ian; Le Cerf, Didier; Michaud, Philippe; Arnaudin-Fruitier, Ingrid; Bridiau, Nicolas; Maugard, Thierry
成纤维细胞
细胞生物学
发表日期：2023
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TOTUM-63, a plant-based polyphenol-rich extract, improves glycaemic control in subjects with prediabetes or early stage newly-diagnosed type 2 diabetes in a randomized, double-blind, placebo-controlled trial

在一项随机、双盲、安慰剂对照试验中，富含多酚的植物提取物 TOTUM-63 可改善糖尿病前期或早期新诊断的 2 型糖尿病患者的血糖控制。

期刊:Diabetes Obesity & Metabolism
影响因子:5.7
doi:10.1111/dom.14817
Sirvent, Pascal; Chavanelle, Vivien; Otero, Yolanda F; Bargetto, Maxime; Le Joubioux, Florian; Boisseau, Nathalie; Maugard, Thierry; Cazaubiel, Murielle; Pereira, Bruno; Guigas, Bruno; Hadjadj, Samy; Peltier, Sebastien L; Marette, André; Bard, Jean-Marie
糖尿病
代谢
发表日期：2022
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Effects of Totum-63 on glucose homeostasis and postprandial glycemia: a translational study.

Totum-63 对葡萄糖稳态和餐后血糖的影响：一项转化研究

期刊:American Journal of Physiology-Endocrinology and Metabolism
影响因子:3.1
doi:10.1152/ajpendo.00629.2020
Chavanelle Vivien, Otero Yolanda F, Le Joubioux Florian, Ripoche Doriane, Bargetto Maxime, Vluggens Aurore, Montaurier Christophe, Pickering Gisèle, Ducheix Gilles, Dubray Claude, Dualé Christian, Boulliau Sylvia, Macian Nicolas, Marceau Geoffroy, Sapin Vincent, Dutheil Frédéric, Guigas Bruno, Maugard Thierry, Boisseau Nathalie, Cazaubiel Murielle, Peltier Sébastien L, Sirvent Pascal
发表日期：2021
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Ulva intestinalis Protein Extracts Promote In Vitro Collagen and Hyaluronic Acid Production by Human Dermal Fibroblasts.

肠浒苔蛋白提取物可促进人真皮成纤维细胞体外产生胶原蛋白和透明质酸

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules25092091
Bodin Justine, Adrien Amandine, Bodet Pierre-Edouard, Dufour Delphine, Baudouin Stanislas, Maugard Thierry, Bridiau Nicolas
细胞生物学
Human
发表日期：2020
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Anticoagulant Activity of Sulfated Ulvan Isolated from the Green Macroalga Ulva rigida

从绿藻硬叶浒苔中分离得到的硫酸化浒苔的抗凝血活性

期刊:Marine Drugs
影响因子:5.4
doi:10.3390/md17050291
Adrien, Amandine; Bonnet, Antoine; Dufour, Delphine; Baudouin, Stanislas; Maugard, Thierry; Bridiau, Nicolas
发表日期：2019
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