日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

T cell-derived IFNγ instructs ECM crosslinking by cardiac fibroblasts through LOXL3 in experimental cardiometabolic HFpEF.

在实验性心脏代谢性 HFpEF 中,T 细胞衍生的 IFNγ 通过 LOXL3 指导心脏成纤维细胞进行 ECM 交联。

Emig Ramona, Robbe Zachary, Kley Celina, Smolgovsky Sasha, Travers Joshua G, Blanton Robert M, McKinsey Timothy A, Black Lauren D, Alcaide Pilar

Logic-based machine learning predicts how escitalopram attenuates cardiomyocyte hypertrophy.

基于逻辑的机器学习预测艾司西酞普兰如何减轻心肌细胞肥大

Eggertsen Taylor G, Travers Joshua G, Hardy Elizabeth J, Wolf Matthew J, McKinsey Timothy A, Saucerman Jeffrey J

Heart Rate Reduction Is Associated With Reverse Left Ventricular Remodeling and Mechanism-Specific Molecular Phenotypes in Dilated Cardiomyopathy

扩张型心肌病中,心率降低与左心室逆向重构和机制特异性分子表型相关

Altman, Natasha L; Gill, Edward A; Kahwash, Rami; Meyer, Leslie K; Wagner, Jessica A; Karimpour-Fard, Anis; Berning, Amber A; Minobe, Wayne A; Carroll, Ian A; Jonas, Eric R; Slavov, Dobromir; Emani, Sitaramesh; Abraham, William T; Gollah, Alexa R; Ellis, Samuel L; Taylor, Matthew R G; Graw, Sharon L; Mestroni, Luisa; McKinsey, Timothy A; Buttrick, Peter M; Kao, David P; Bristow, Michael R

Deuterium labeling enables proteome-wide turnover kinetics analysis in cell culture.

氘标记技术能够对细胞培养中的蛋白质组进行全面的周转动力学分析

Alamillo Lorena, Ng Dominic C M, Currie Jordan, Black Alexander, Pandi Boomathi, Manda Vyshnavi, Pavelka Jay, Schaal Peyton, Travers Joshua G, McKinsey Timothy A, Lam Maggie P Y, Lau Edward

Salt-inducible Kinase Regulation of Adipose Tissue Metabolism

盐诱导激酶对脂肪组织代谢的调控

Shi, Fubiao; Agrawal, Vineet; McKinsey, Timothy A; Collins, Sheila

Myocardial transcriptomic and proteomic landscapes across the menopausal continuum in a murine model of chemically induced accelerated ovarian failure.

在化学诱导加速卵巢功能衰竭的小鼠模型中,更年期连续过程中心肌转录组和蛋白质组的变化

Lopez-Pier Marissa A, Marino Vito A, Vazquez-Loreto Andrea C, Skaria Rinku S, Cannon Danielle K, Hoyer-Kimura Christina H, Solomon Alice E, Lipovka Yulia, Doubleday Kevin, Pier Maricela, Chu Meinsung, Mayfield Rachel, Behunin Samantha M, Hu Tianjing, Langlais Paul R, McKinsey Timothy A, Konhilas John P

Low Dose GLP-1 Therapy Attenuates Pathological Cardiac and Hepatic Remodelling in HFpEF Independent of Weight Loss

低剂量GLP-1疗法可减轻HFpEF患者的病理性心脏和肝脏重塑,且与体重减轻无关。

Elbatreek, Mahmoud H; Li, Zhen; Yu, Xiaoman; Gehred, Natalie D; Gromova, Tatiana; Chen, Jingshu; Muraoka, Naoto; Jensen, Martin; Kartha, Vinay; Carrico, Chris; Allerton, Timothy D; Bowdish, Michael E; Chikwe, Joanna; Shah, Sanjiv J; Woulfe, Kathleen C; McKinsey, Timothy A; Yoo, Edwin; Polhemus, David J; Vondriska, Thomas M; Goodchild, Traci T; Lefer, David J

β(1)- and β(2)-adrenergic Receptor Haplotypes Regulate Therapeutic Responses to Placebo and the Biased Ligand β-blocker Bucindolol

β(1)-和β(2)-肾上腺素能受体单倍型调节安慰剂和偏向性配体β受体阻滞剂布新洛尔的治疗反应

Carroll, Ian A; Slavov, Dobromir; Jonas, Eric R; Minobe, Wayne A; Walker, Lori A; Ambardekar, Amrut V; McKinsey, Timothy A; Knaupp, Ammon D; Kim, Donghwa; Liggett, Stephen B; Bristow, Michael R

Troponin I Tyrosine Phosphorylation Beneficially Accelerates Diastolic Function

肌钙蛋白I酪氨酸磷酸化有益地加速舒张功能

Salyer, Lorien G; Salhi, Hussam E; Brundage, Elizabeth A; Shettigar, Vikram; Sturgill, Sarah L; Zanella, Helena; Templeton, Benjamin; Abay, Eaman; Emmer, Kathryn M; Lowe, Jeovanna; Rafael-Fortney, Jill A; Parinandi, Narasimham; Foster, D Brian; McKinsey, Timothy A; Woulfe, Kathleen C; Ziolo, Mark T; Biesiadecki, Brandon J

Cyclophilin(g) a Knowledge Gap in Heart Failure Pathogenesis

环孢亲和素(g):心力衰竭发病机制中的知识空白

Delaunay, Marion; Jebessa, Zegeye H; McKinsey, Timothy A