日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Double strand breaks drive toxicity in Huntington's disease mice with or without somatic expansion.

双链断裂会导致亨廷顿病小鼠出现毒性,无论是否存在体细胞扩增

Polyzos Aris A, Cheong Ana, Yoo Jung Hyun, Blagec Lana, Nagel Zachary D, McMurray Cynthia T

XJB-5-131 Is a Mild Uncoupler of Oxidative Phosphorylation

XJB-5-131 是一种温和的氧化磷酸化解偶联剂

Xun, Zhiyin; Wipf, Peter; McMurray, Cynthia T

A Double-Pronged Sword: XJB-5-131 Is a Suppressor of Somatic Instability and Toxicity in Huntington's Disease

双刃剑:XJB-5-131 可抑制亨廷顿病中的体细胞不稳定性和毒性

Wipf, Pater; Polyzos, Aris A; McMurray, Cynthia T

Folate deficiency drives mitotic missegregation of the human FRAXA locus

叶酸缺乏导致人类FRAXA基因座有丝分裂分离错误

Bjerregaard, Victoria A; Garribba, Lorenza; McMurray, Cynthia T; Hickson, Ian D; Liu, Ying

XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent

XJB-5-131介导的亨廷顿病R6/2小鼠模型生理和行为的改善具有年龄和性别依赖性。

Polyzos, Aris A; Wood, Nigel I; Williams, Paul; Wipf, Peter; Morton, A Jennifer; McMurray, Cynthia T

The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's disease

先有鸡还是先有蛋:线粒体功能障碍是亨廷顿病毒性的原因还是结果

Polyzos, Aris A; McMurray, Cynthia T

Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2

DNA糖基化酶同源物mag2对无碱基位点的DNA进行雕刻

Dalhus, Bjørn; Nilsen, Line; Korvald, Hanne; Huffman, Joy; Forstrøm, Rune Johansen; McMurray, Cynthia T; Alseth, Ingrun; Tainer, John A; Bjørås, Magnar

A brief history of triplet repeat diseases

三核苷酸重复疾病简史

Budworth, Helen; McMurray, Cynthia T

Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease

将 XJB-5-131 靶向线粒体可抑制亨廷顿病小鼠模型中的氧化性 DNA 损伤和运动功能衰退。

Xun, Zhiyin; Rivera-Sánchez, Sulay; Ayala-Peña, Sylvette; Lim, James; Budworth, Helen; Skoda, Erin M; Robbins, Paul D; Niedernhofer, Laura J; Wipf, Peter; McMurray, Cynthia T

Retinoic acid-induced differentiation increases the rate of oxygen consumption and enhances the spare respiratory capacity of mitochondria in SH-SY5Y cells

视黄酸诱导分化可提高SH-SY5Y细胞的耗氧率并增强线粒体的储备呼吸能力。

Xun, Zhiyin; Lee, Do-Yup; Lim, James; Canaria, Christie A; Barnebey, Adam; Yanonne, Steven M; McMurray, Cynthia T