日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterization of K562 cells: uncovering novel chromosomes, assessing transferrin receptor expression, and probing pharmacological therapies

K562 细胞的表征:发现新的染色体、评估转铁蛋白受体的表达以及探索药物疗法

Tom C Karagiannis, Meaghan Wall, Katherine Ververis, Eleni Pitsillou, Stephanie M Tortorella, Peter A Wood, Haloom Rafehi, Ishant Khurana, Scott S Maxwell, Andrew Hung, Jitraporn Vongsvivut, Assam El-Osta

Srsf2P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice

Srsf2P95H/+ 与 TET2 缺失协同作用,促进骨髓偏向并在小鼠中引发慢性粒单核细胞白血病样疾病

Jane Jialu Xu, Alistair M Chalk, Meaghan Wall, Wallace Y Langdon, Monique F Smeets #, Carl R Walkley #

Cep55 overexpression promotes genomic instability and tumorigenesis in mice

Cep55 过表达促进小鼠基因组不稳定性和肿瘤发生

Debottam Sinha, Purba Nag, Devathri Nanayakkara, Pascal H G Duijf, Andrew Burgess, Prahlad Raninga, Veronique A J Smits, Amanda L Bain, Goutham Subramanian, Meaghan Wall, John W Finnie, Murugan Kalimutho, Kum Kum Khanna

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

抑制 Pol I 转录可通过靶向白血病起始细胞群来治疗小鼠和人类 AML

Nadine Hein, Donald P Cameron, Katherine M Hannan, Nhu-Y N Nguyen, Chun Yew Fong, Jirawas Sornkom, Meaghan Wall, Megan Pavy, Carleen Cullinane, Jeannine Diesch, Jennifer R Devlin, Amee J George, Elaine Sanij, Jaclyn Quin, Gretchen Poortinga, Inge Verbrugge, Adele Baker, Denis Drygin, Simon J Harriso

Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia

循环肿瘤 DNA 反映慢性淋巴细胞白血病的治疗反应和克隆进化

Paul Yeh, Tane Hunter, Devbarna Sinha, Sarah Ftouni, Elise Wallach, Damian Jiang, Yih-Chih Chan, Stephen Q Wong, Maria Joao Silva, Ravikiran Vedururu, Kenneth Doig, Enid Lam, Gisela Mir Arnau, Timothy Semple, Meaghan Wall, Andjelija Zivanovic, Rishu Agarwal, Pasquale Petrone, Kate Jones, David Weste

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

Eμ-Myc 小鼠淋巴瘤的基因组表征表明 Bcor 是一种 Myc 协同肿瘤抑制基因

Marcus Lefebure, Richard W Tothill, Elizabeth Kruse, Edwin D Hawkins, Jake Shortt, Geoffrey M Matthews, Gareth P Gregory, Benjamin P Martin, Madison J Kelly, Izabela Todorovski, Maria A Doyle, Richard Lupat, Jason Li, Jan Schroeder, Meaghan Wall, Stuart Craig, Gretchen Poortinga, Don Cameron, Megan

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

Rothmund-Thomson 综合征解旋酶 RECQL4 对造血至关重要

Monique F Smeets, Elisabetta DeLuca, Meaghan Wall, Julie M Quach, Alistair M Chalk, Andrew J Deans, Jörg Heierhorst, Louise E Purton, David J Izon, Carl R Walkley

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence

mTORC1 抑制剂依维莫司通过恢复致癌基因诱导的衰老来预防和治疗 Eμ-Myc 淋巴瘤

Meaghan Wall, Gretchen Poortinga, Kym L Stanley, Ralph K Lindemann, Michael Bots, Christopher J Chan, Megan J Bywater, Kathryn M Kinross, Megan V Astle, Kelly Waldeck, Katherine M Hannan, Jake Shortt, Mark J Smyth, Scott W Lowe, Ross D Hannan, Richard B Pearson, Ricky W Johnstone, Grant A McArthur

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

PI3K 相关 DNA 损伤反应激酶和 mTORC1 的联合抑制可诱导 MYC 驱动的 B 细胞淋巴瘤细胞凋亡

Jake Shortt, Benjamin P Martin, Andrea Newbold, Katherine M Hannan, Jennifer R Devlin, Adele J Baker, Rachael Ralli, Carleen Cullinane, Clemens A Schmitt, Maurice Reimann, Michael N Hall, Meaghan Wall, Ross D Hannan, Richard B Pearson, Grant A McArthur, Ricky W Johnstone

c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiation

c-MYC 在粒细胞分化过程中协调调节核糖体基因染色质重塑和 Pol I 可用性

Gretchen Poortinga, Meaghan Wall, Elaine Sanij, Kasia Siwicki, Jason Ellul, Daniel Brown, Timothy P Holloway, Ross D Hannan, Grant A McArthur