日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

3D "Emboli" Culture Models Epithelial Breast Cancer Cell Oxidative Mitochondrial Metabolism with Relevance for Lung Metastasis.

3D“栓子”培养模型模拟乳腺癌上皮细胞氧化线粒体代谢及其与肺转移的相关性。

Balamurugan Kuppusamy, Mikolaj Melissa R, Weiss Jonathan M, Holewinski Ronald J, Fan Yu, Dash Shiba Prasad, Xu Xia, McKennett Lois, Dell Christopher W, Donohue Duncan, Vitale Ariana, Ratnayake Shashikala, Sharan Shikha, Chen Qingrong, Meerzaman Daoud, Andresson Thorkell, McVicar Daniel W, Narayan Kedar, Sterneck Esta

Temporal Integration of Serum Proteomics, Metabolomics and MRI Tumor Volumetrics via Deep Learning Identifies Systemic Mediators of Glioblastoma Response to Chemoradiotherapy

通过深度学习对血清蛋白质组学、代谢组学和MRI肿瘤体积测量进行时间整合,可识别胶质母细胞瘤对放化疗反应的系统性介质

Krauze, Andra; Nguyen, Trinh; Sierk, Michael; Jackson, Luke; Chappidi, Shreya; Chen, Qingrong; Yan, Chunhua; Hu, Ying; Harmon, Stephanie; Tasci, Erdal; Cooley, Theresa; Sproull, Mary; Mackey, Megan; Meerzaman, Daoud; Camphausen, Kevin

Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome

一氧化氮抑制ten-eleven translocation DNA去甲基化酶,从而调节基因组中的5mC和5hmC水平

Palczewski, Marianne B; Kuschman, Hannah Petraitis; Hoffman, Brian M; Kathiresan, Venkatesan; Yang, Hao; Glynn, Sharon A; Wilson, David L; Kool, Eric T; Montfort, William R; Chang, Jenny; Petenkaya, Aydolun; Chronis, Constantinos; Cundari, Thomas R; Sappa, Sushma; Islam, Kabirul; McVicar, Daniel W; Fan, Yu; Chen, Qingrong; Meerzaman, Daoud; Sierk, Michael; Thomas, Douglas D

TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells

TRAIL通过NF-κB2通路诱导细胞因子产生,促进中性粒细胞趋化和中性粒细胞介导的免疫抑制,从而增强三阴性乳腺癌细胞的免疫活性。

Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett, Stephen J; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley

DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens

DeepTarget通过整合药物筛选和基因筛选来预测小分子抗癌作用机制。

Sinha, Sanju; Sinha, Neelam; Perales, Marlenne; Tarrab, Adi; Nguyen, Trinh; Liu, Lihe; Cantore, Thomas; Alvarez, Kyle; Patiyal, Sumeet; Mukherjee, Sumit; Madan, Sanna; Tharp, Kevin; Zhao, Jianhua; Kumar, Ranjit; Flanigan, Greg; Beutler, John A; O'Keefe, Barry R; Meerzaman, Daoud; Ben-David, Uri; Deshpande, Aniruddha J; Ruppin, Eytan

Proteogenomic characterization of invasive breast tumors in young women

年轻女性浸润性乳腺肿瘤的蛋白质基因组学特征分析

Raj-Kumar, Praveen-Kumar; Liu, Jianfang; Soltis, Anthony R; Bateman, Nicholas W; Chen, Qingrong; Sturtz, Lori A; Deyarmin, Brenda; Pierobon, Mariaelena; Abulez, Tamara A; Praveen-Kumar, Anupama; Zhang, Xijun; Nguyen, Trinh; Yan, Chunhua; Hu, Ying; Guion, Kate; Hooke, Jeffrey A; Kovatich, Albert J; Fantacone-Campbell, Leigh; Mostoller, Brad; Kvecher, Leonid; Somiari, Stella; Steeg, Patricia S; Rajagopal, Padma Sheila; Darcy, Kathleen M; Lee, Jerry S H; Dalgard, Clifton L; Conrads, Thomas P; Petricoin, Emanuel F; Meerzaman, Daoud; Wilkerson, Matthew D; Lin, Xiaoying; Shriver, Craig D; Lipkowitz, Stanley; Hu, Hai

Timp2 loss-of-function mutation and TIMP2 treatment in a murine model of NSCLC: Modulation of immunosuppression and oncogenic signaling

在小鼠非小细胞肺癌模型中,TIMP2功能缺失突变和TIMP2治疗:免疫抑制和致癌信号的调节

Peeney, David; Kumar, Sarvesh; Singh, Tej Pratap; Liu, Yueqin; Jensen, Sandra M; Chowdhury, Ananda; Coates-Park, Sasha; Rich, Joshua; Gurung, Sadeechya; Fan, Yu; Meerzaman, Daoud; Stetler-Stevenson, William G

Modular and cloud-based bioinformatics pipelines for high-confidence biomarker detection in cancer immunotherapy clinical trials

用于癌症免疫疗法临床试验中高置信度生物标志物检测的模块化和基于云的生物信息学流程

Nguyen, Cu; Nguyen, Trinh; Trivitt, Gloria; Capaldo, Brian; Yan, Chunhua; Chen, Qingrong; Renzette, Nicholas; Topaloglu, Umit; Meerzaman, Daoud

Oncopacket: integration of cancer research data using GA4GH phenopackets

Oncopacket:利用 GA4GH 表型包整合癌症研究数据

Sierk, Michael; Danis, Daniel; Patil, Sujay; Kishor, Nobal; Mondal, Rajdeep; Jha, Abhishek; Chen, Qingrong; Yan, Chunhua; Munoz-Torres, Monica; Meerzaman, Daoud; Robinson, Peter N; Reese, Justin T

A simple liquid 3D cell culture paradigm models oxidative mitochondrial metabolism of epithelial breast cancer cells with relevance for lung metastases.

一种简单的液态 3D 细胞培养模型模拟了与肺转移相关的乳腺癌上皮细胞的氧化线粒体代谢

Balamurugan Kuppusamy, Mikolaj Melissa R, Weiss Jonathan M, Holewinski Ronald, Xu Xia, Fan Yu, McKennett Lois, Dell Christopher W, Sharan Shikha, Donohue Duncan, Ratnayake Shashikala, Chen Qingrong, Meerzaman Daoud, Andresson Thorkel, McVicar Daniel W, Narayan Kedar, Sterneck Esta