日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Bi-steric, mTORC1-Selective Inhibitor, RMC-5552, in Advanced Solid Tumors: A Phase 1 Trial

双位阻 mTORC1 选择性抑制剂 RMC-5552 在晚期实体瘤中的应用:一项 1 期临床试验

Schram, Alison M; Naqash, Abdul Rafeh; Haura, Eric B; Riess, Jonathan W; Ulahannan, Susanna V; Ou, Sai-Hong I; Munster, Pamela N; Cheng, Michael L; Gustafson, W Clay; Bitman, Bojena; Friedman, Robert; Penn, Ruth; Kar, Sumit; Seshadri, Vidya; Wang, Zhican; Tao, Lin; Yang, Yu Chi; Singh, Mallika; Burris, Howard A; Meyerowitz, Justin G

The oxytocin signaling complex reveals a molecular switch for cation dependence.

催产素信号复合物揭示了阳离子依赖性的分子开关

Meyerowitz Justin G, Robertson Michael J, Barros-Álvarez Ximena, Panova Ouliana, Nwokonko Robert M, Gao Yang, Skiniotis Georgios

Structure determination of inactive-state GPCRs with a universal nanobody.

利用通用纳米抗体测定非活性状态GPCR的结构

Robertson Michael J, Papasergi-Scott Makaía M, He Feng, Seven Alpay B, Meyerowitz Justin G, Panova Ouliana, Peroto Maria Claudia, Che Tao, Skiniotis Georgios

Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19

整合血浆蛋白质组学和单细胞免疫信号网络特征可区分轻症、中症和重症 COVID-19

Feyaerts, Dorien; Hédou, Julien; Gillard, Joshua; Chen, Han; Tsai, Eileen S; Peterson, Laura S; Ando, Kazuo; Manohar, Monali; Do, Evan; Dhondalay, Gopal K R; Fitzpatrick, Jessica; Artandi, Maja; Chang, Iris; Snow, Theo T; Chinthrajah, R Sharon; Warren, Christopher M; Wittman, Rich; Meyerowitz, Justin G; Ganio, Edward A; Stelzer, Ina A; Han, Xiaoyuan; Verdonk, Franck; Gaudillière, Dyani K; Mukherjee, Nilanjan; Tsai, Amy S; Rumer, Kristen K; Jiang, Sizun; Valdés Ferrer, Sergio Iván; Kelly, J Daniel; Furman, David; Aghaeepour, Nima; Angst, Martin S; Boyd, Scott D; Pinsky, Benjamin A; Nolan, Garry P; Nadeau, Kari C; Gaudillière, Brice; McIlwain, David R

N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells

N-Myc驱动起源于人类前列腺上皮细胞的神经内分泌前列腺癌

Lee, John K; Phillips, John W; Smith, Bryan A; Park, Jung Wook; Stoyanova, Tanya; McCaffrey, Erin F; Baertsch, Robert; Sokolov, Artem; Meyerowitz, Justin G; Mathis, Colleen; Cheng, Donghui; Stuart, Joshua M; Shokat, Kevan M; Gustafson, W Clay; Huang, Jiaoti; Witte, Owen N

A new "angle" on kinase inhibitor design: Prioritizing amphosteric activity above kinase inhibition

激酶抑制剂设计的新“角度”:优先考虑两性活性而非激酶抑制

Meyerowitz, Justin G; Weiss, William A; Gustafson, W Clay