A Strategy for Simultaneous Engineering of Interspecies Cross-Reactivity, Thermostability, and Expression of a Bispecific 5T4 x CD3 DART® Molecule for Treatment of Solid Tumors
用于治疗实体肿瘤的双特异性 5T4 x CD3 DART® 分子的跨物种交叉反应性、热稳定性和表达的同步工程化策略
期刊:Antibodies
影响因子:
doi:10.3390/antib14010007
Renhua R Huang, Michael Spliedt, Tom Kaufman, Sergey Gorlatov, Bhaswati Barat, Kalpana Shah, Jeffrey Gill, Kurt Stahl, Jennifer DiChiara, Qian Wang, Jonathan C Li, Ralph Alderson, Paul A Moore, Jennifer G Brown, James Tamura, Xiaoyu Zhang, Ezio Bonvini, Gundo Diedrich
