日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapamycin Reverses the Hepatic Response to Diet-Induced Metabolic Stress That Is Amplified by Aging.

雷帕霉素可逆转肝脏对饮食引起的代谢应激的反应,而这种反应会随着年龄的增长而加剧。

Havas Aaron, Rajesh Adarsh, Lei Xue, Proulx Jessica, Miller Karl N, Field Adam, Davis Andrew, Teneche Marcos Garcia, Gandhi Armin, Lee Jin, Feng Gen-Sheng, Adams Peter D

A Manifold-Based Measure of Transcriptional Entropy for Quantifying Aging in Single Cells

基于流形的转录熵测量方法用于量化单细胞衰老

Yang, Yilin; Hess, Paul R; Huang, Sijia; Teneche, Marcos G; Wang, Hanzhi; Miller, Karl N; Davis, Andrew E; Miciano, Charlene; Li, Kelly Yichen; Mamde, Sainath; Yip, Kevin; Ren, Bing; Yang, Qian; Smoot, Elizabeth; Wang, Allen; Johnson, Bradley; Wilson, Parker; Adams, Peter D; Zhang, Nancy R

Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline.

靶向细胞周期蛋白D1-CDK6以减轻衰老驱动的炎症和与年龄相关的机能衰退

Rajesh Adarsh, Havas Aaron P, Arnold Rouven, Lande Kathryn, Evensen K Garrett, Li Kelly Yichen, Mamde Sainath, Yang Qian, Gandhi Armin, Miller Karl N, Teneche Marcos Garcia, Yao Zoe, Proulx Jessica, Davis Andrew, Haddadin Laurence, Alcaraz Michael, Macip Carolina C, Li Brightany, Lei Xue, Miciano Charlene, Smoot Elizabeth, Wang Allen, Albrecht Jeffrey H, Williams April E, Ren Bing, Yip Kevin Y, Adams Peter D

Author Correction: Senescent glia link mitochondrial dysfunction and lipid accumulation

作者更正:衰老胶质细胞与线粒体功能障碍和脂质积累有关。

Byrns, China N; Perlegos, Alexandra E; Miller, Karl N; Jin, Zhecheng; Carranza, Faith R; Manchandra, Palak; Beveridge, Connor H; Randolph, Caitlin E; Chaluvadi, V Sai; Zhang, Shirley L; Srinivasan, Ananth R; Bennett, F C; Sehgal, Amita; Adams, Peter D; Chopra, Gaurav; Bonini, Nancy M

Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence.

组蛋白伴侣 HIRA、早幼粒细胞白血病蛋白和 p62/SQSTM1 协同调节细胞衰老过程中的炎症

Dasgupta Nirmalya, Lei Xue, Shi Christina Huan, Arnold Rouven, Teneche Marcos G, Miller Karl N, Rajesh Adarsh, Davis Andrew, Anschau Valesca, Campos Alexandre R, Gilson Rebecca, Havas Aaron, Yin Shanshan, Chua Zong Ming, Liu Tianhui, Proulx Jessica, Alcaraz Michael, Rather Mohammed Iqbal, Baeza Josue, Schultz David C, Yip Kevin Y, Berger Shelley L, Adams Peter D

Linked regulation of genome integrity and senescence-associated inflammation by p53

p53 对基因组完整性和衰老相关炎症的调控作用

Miller, Karl N; Li, Brightany; Pierce-Hoffman, Hannah R; Patel, Shreeya; Lei, Xue; Rajesh, Adarsh; Teneche, Marcos G; Havas, Aaron P; Gandhi, Armin; Macip, Carolina Cano; Lyu, Jun; Victorelli, Stella G; Woo, Seung-Hwa; Lagnado, Anthony B; LaPorta, Michael A; Liu, Tianhui; Dasgupta, Nirmalya; Li, Sha; Davis, Andrew; Korotkov, Anatoly; Hultenius, Erik; Gao, Zichen; Altman, Yoav; Porritt, Rebecca A; Garcia, Guillermina; Mogler, Carolin; Seluanov, Andrei; Gorbunova, Vera; Kaech, Susan M; Tian, Xiao; Dou, Zhixun; Chen, Chongyi; Passos, João F; Adams, Peter D

Histone chaperone HIRA, Promyelocytic Leukemia (PML) protein and p62/SQSTM1 coordinate to regulate inflammation during cell senescence

组蛋白伴侣HIRA、早幼粒细胞白血病(PML)蛋白和p62/SQSTM1协同调节细胞衰老过程中的炎症反应。

Dasgupta, Nirmalya; Lei, Xue; Shi, Christina Huan; Arnold, Rouven; Teneche, Marcos G; Miller, Karl N; Rajesh, Adarsh; Davis, Andrew; Anschau, Valesca; Campos, Alexandre R; Gilson, Rebecca; Havas, Aaron; Yin, Shanshan; Chua, Zong Ming; Liu, Tianhui; Proulx, Jessica; Alcaraz, Michael; Rather, Mohammed Iqbal; Baeza, Josue; Schultz, David C; Yip, Kevin Y; Berger, Shelley L; Adams, Peter D

Cytoplasmic DNA: sources, sensing, and role in aging and disease

细胞质DNA:来源、感知及其在衰老和疾病中的作用

Miller, Karl N; Victorelli, Stella G; Salmonowicz, Hanna; Dasgupta, Nirmalya; Liu, Tianhui; Passos, João F; Adams, Peter D

Cytoplasmic chromatin fragments-from mechanisms to therapeutic potential

细胞质染色质片段——从机制到治疗潜力

Miller, Karl N; Dasgupta, Nirmalya; Liu, Tianhui; Adams, Peter D; Vizioli, Maria Grazia

Mitochondrial regulator PGC-1a-Modulating the modulator

线粒体调节因子PGC-1α——调节调节因子

Miller, Karl N; Clark, Josef P; Anderson, Rozalyn M