日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Low Exposures to Amphibole or Serpentine Asbestos in Germline Bap1-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

种系 Bap1 突变小鼠低剂量接触闪石或蛇纹石石棉可诱发以免疫抑制肿瘤微环境为特征的间皮瘤

Yuwaraj Kadariya, Eleonora Sementino, Maggie Ruan, Mitchell Cheung, Parham Hadikhani, Hatice U Osmanbeyoglu, Andres J Klein-Szanto, Kathy Cai, Joseph R Testa

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling

p21 活化激酶 2 (Pak2) 的失活通过限制下游 Hedgehog 和 Wnt 信号传导来抑制 Nf2 缺陷肿瘤的发展

Eleonora Sementino #, Yuwaraj Kadariya #, Mitchell Cheung, Craig W Menges, Yinfei Tan, Anna-Mariya Kukuyan, Ujjawal Shrestha, Sofiia Karchugina, Kathy Q Cai, Suraj Peri, James S Duncan, Jonathan Chernoff, Joseph R Testa

Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma

RIPK3 的体细胞表观遗传沉默可使坏死性凋亡失活并导致恶性间皮瘤产生化学耐药性

Yinfei Tan #, Eleonora Sementino #, Mitchell Cheung, Suraj Peri, Craig W Menges, Anna-Mariya Kukuyan, Ting Zhang, Vladimir Khazak, Lauren A Fox, Eric A Ross, Suresh Ramanathan, Suresh C Jhanwar, Raja M Flores, Siddharth Balachandran, Joseph R Testa

Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase

ASXL1/2 介导的 BAP1 去泛素化酶变构调控的动力学表征

Hongzhuang Peng, Joel Cassel, Daniel S McCracken, Jeremy W Prokop, Eleonora Sementino, Mitchell Cheung, Paul R Collop, Alexander Polo, Surbhi Joshi, Jacob P Mandell, Kasirajan Ayyanathan, David Hinds, S Bruce Malkowicz, J William Harbour, Anne M Bowcock, Joseph Salvino, Eileen J Kennedy, Joseph R Te

Novel LRRK2 mutations and other rare, non-BAP1-related candidate tumor predisposition gene variants in high-risk cancer families with mesothelioma and other tumors

间皮瘤和其他肿瘤高风险癌症家族中新的 LRRK2 突变和其他罕见、非 BAP1 相关候选肿瘤易感基因变异

Mitchell Cheung, Yuwaraj Kadariya, Eleonora Sementino, Michael J Hall, Ilaria Cozzi, Valeria Ascoli, Jill A Ohar, Joseph R Testa

Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models

Bap1 失活与 Nf2 和 Cdkn2a 缺失协同作用,推动条件性小鼠模型中胸膜恶性间皮瘤的发展

Anna-Mariya Kukuyan, Eleonora Sementino, Yuwaraj Kadariya, Craig W Menges, Mitchell Cheung, Yinfei Tan, Kathy Q Cai, Michael J Slifker, Suraj Peri, Andres J Klein-Szanto, Frank J Rauscher 3rd, Joseph R Testa

Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection

Toll样受体4基因的多种变异会影响患有慢性丙型肝炎的白种人发生肝纤维化的风险。

Li, Yonghong; Chang, Monica; Abar, Olivia; Garcia, Veronica; Rowland, Charles; Catanese, Joseph; Ross, David; Broder, Samuel; Shiffman, Mitchell; Cheung, Ramsey; Wright, Teresa; Friedman, Scott L; Sninsky, John