日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax

将带有线粒体靶向信号的单体p53亚结构域从促凋亡蛋白Bak或Bax递送至细胞膜

Matissek, Karina J; Okal, Abood; Mossalam, Mohanad; Lim, Carol S

Controlled access of p53 to the nucleus regulates its proteasomal degradation by MDM2

p53 进入细胞核的受控状态通过 MDM2 调节其蛋白酶体降解。

Davis, James R; Mossalam, Mohanad; Lim, Carol S

A chimeric p53 evades mutant p53 transdominant inhibition in cancer cells.

嵌合型 p53 可逃避癌细胞中突变型 p53 的显性抑制

Okal Abood, Mossalam Mohanad, Matissek Karina J, Dixon Andrew S, Moos Philip J, Lim Carol S

The DNA binding domain of p53 is sufficient to trigger a potent apoptotic response at the mitochondria

p53 的 DNA 结合域足以引发线粒体的强烈凋亡反应

Karina J Matissek, Mohanad Mossalam, Abood Okal, Carol S Lim

A single mutant, A276S of p53, turns the switch to apoptosis

p53 的 A276S 突变体启动了细胞凋亡的开关

Shams Reaz, Mohanad Mossalam, Abood Okal, Carol S Lim

Solid phase synthesis of mitochondrial triphenylphosphonium-vitamin E metabolite using a lysine linker for reversal of oxidative stress

利用赖氨酸连接子固相合成线粒体三苯基膦-维生素E代谢物以逆转氧化应激

Mossalam, Mohanad; Soto, Jamie; Lim, Carol S; Abel, E Dale

Utilizing the estrogen receptor ligand-binding domain for controlled protein translocation to the insoluble fraction

利用雌激素受体配体结合域控制蛋白质转位至不溶性部分

James R Davis, Mohanad Mossalam, Carol S Lim

Controlling subcellular delivery to optimize therapeutic effect

控制亚细胞递送以优化治疗效果

Mossalam, Mohanad; Dixon, Andrew S; Lim, Carol S