Mottamal相关文献与解析，生知库 | 链接生命科学的每一步

Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations

发现具有强效抗继发性耐药突变活性的 ROS1 融合蛋白口服降解剂

doi:10.1021/acs.jmedchem.4c01205

Xianyou Peng, Shanchun Guo, Shilong Zheng, Ahamed Hossain, Changde Zhang, Madhusoodanan Mottamal, Elena Skripnikova, Peng Ma, Kindy Martinez-Carter, Qiang Zhang, Faisal Abedin, Thomas Huckaba, Guangdi Wang

发表日期：2024

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Discovery of Heparin Mimetic, Potent, and Selective Inhibitors of Human Clotting Factor XIIIa

发现人类凝血因子 XIIIa 的肝素模拟物、强效和选择性抑制剂

期刊:ACS Omega

影响因子:3.7

doi:10.1021/acsomega.4c04518

Kayla T Vu, Srabani Kar, Navneet Goyal, Madhusoodanan Mottamal, Daniel K Afosah, Rami A Al-Horani

信号转导

发表日期：2024

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Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors

发现一种新的先导分子，用于开发一类新型的人类凝血因子XIIa抑制剂

期刊:Journal of Thrombosis and Thrombolysis

影响因子:2.2

doi:10.1007/s11239-024-03054-2

Dumas, Anthony; Goyal, Navneet; Mottamal, Madhusoodanan; Afosah, Daniel K; Al-Horani, Rami A

发表日期：2024

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Design, Synthesis, and Evaluation of Niclosamide Analogs as Therapeutic Agents for Enzalutamide-Resistant Prostate Cancer

氯硝柳胺类似物作为恩杂鲁胺耐药前列腺癌治疗剂的设计、合成及评价

期刊:Pharmaceuticals

影响因子:

doi:10.3390/ph16050735

Borui Kang, Madhusoodanan Mottamal, Qiu Zhong, Melyssa Bratton, Changde Zhang, Shanchun Guo, Ahamed Hossain, Peng Ma, Qiang Zhang, Guangdi Wang, Florastina Payton-Stewart

Research is life itself: in memory of Takashi Yura

研究即生命：谨以此纪念由良隆

期刊:Cardiovascular and Hematological Agents in Medicinal Chemistry

影响因子:

doi:10.2174/1871525721666221031141323

Al-Horani, Rami A; Afosah, Daniel K; Mottamal, Madhusoodanan; Ito, Koreaki

发表日期：2023

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Factor IX(a) inhibitors: an updated patent review (2003-present)

因子IX(a)抑制剂：最新专利综述（2003年至今）

期刊:Expert Opinion on Therapeutic Patents

影响因子:4.6

doi:10.1080/13543776.2022.2026926

Afosah, Daniel K; Ofori, Edward; Mottamal, Madhusoodanan; Al-Horani, Rami A

发表日期：2022

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Sulfonated non-saccharide molecules and human factor XIa: Enzyme inhibition and computational studies

磺化非糖分子和人类因子 XIa：酶抑制和计算研究

期刊:Chemical Biology & Drug Design

影响因子:3.2

doi:10.1111/cbdd.14053

Rami A Al-Horani, Elnaz Parsaeian, Mariam Mohammad, Madhusoodanan Mottamal

信号转导

发表日期：2022

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Ethacrynic acid is an inhibitor of human factor XIIIa

依他尼酸是人类 XIIIa 因子的抑制剂。

期刊:BMC Pharmacology & Toxicology

影响因子:2.8

doi:10.1186/s40360-022-00575-5

Srabani Kar, Kayla Vu, Madhusoodanan Mottamal, Rami A Al-Horani

信号转导

发表日期：2022

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From Pure Antagonists to Pure Degraders of the Estrogen Receptor: Evolving Strategies for the Same Target

从雌激素受体的纯拮抗剂到纯降解剂：针对同一靶点的策略演变

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.0c06362

Mottamal, Madhusoodanan; Kang, Borui; Peng, Xianyou; Wang, Guangdi

New Non-Saccharide Heparin Mimetics as Inhibitors of Cathepsin G

新型非糖类肝素类似物作为组织蛋白酶G抑制剂

Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations

发现具有强效抗继发性耐药突变活性的 ROS1 融合蛋白口服降解剂

Discovery of Heparin Mimetic, Potent, and Selective Inhibitors of Human Clotting Factor XIIIa

发现人类凝血因子 XIIIa 的肝素模拟物、强效和选择性抑制剂

Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors

发现一种新的先导分子，用于开发一类新型的人类凝血因子XIIa抑制剂

Design, Synthesis, and Evaluation of Niclosamide Analogs as Therapeutic Agents for Enzalutamide-Resistant Prostate Cancer

氯硝柳胺类似物作为恩杂鲁胺耐药前列腺癌治疗剂的设计、合成及评价

Research is life itself: in memory of Takashi Yura

研究即生命：谨以此纪念由良隆

Factor IX(a) inhibitors: an updated patent review (2003-present)

因子IX(a)抑制剂：最新专利综述（2003年至今）

Sulfonated non-saccharide molecules and human factor XIa: Enzyme inhibition and computational studies

磺化非糖分子和人类因子 XIa：酶抑制和计算研究

Ethacrynic acid is an inhibitor of human factor XIIIa

依他尼酸是人类 XIIIa 因子的抑制剂。

From Pure Antagonists to Pure Degraders of the Estrogen Receptor: Evolving Strategies for the Same Target

从雌激素受体的纯拮抗剂到纯降解剂：针对同一靶点的策略演变