Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents
BRAF 突变结肠癌对 BRAF 抑制的耐药性可通过 PI3K 抑制剂或去甲基化剂来克服
期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-11-1446
Muling Mao, Feng Tian, John M Mariadason, Chun C Tsao, Robert Lemos Jr, Farshid Dayyani, Y N Vashisht Gopal, Zhi-Qin Jiang, Ignacio I Wistuba, Xi M Tang, William G Bornman, Gideon Bollag, Gordon B Mills, Garth Powis, Jayesh Desai, Gary E Gallick, Michael A Davies, Scott Kopetz
