Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus-infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune function-associated networks
在感染肝螺杆菌的AB6F1和B6AF1杂交雄性小鼠中,慢性肝炎的遗传易感性以共显性方式遗传,而肝细胞癌的进展与肝脏中脂肪生成基因和免疫功能相关网络的表达有关。
期刊:Infection and Immunity
影响因子:2.8
doi:10.1128/IAI.01044-07
García, Alexis; Ihrig, Melanie M; Fry, Rebecca C; Feng, Yan; Xu, Sandy; Boutin, Samuel R; Rogers, Arlin B; Muthupalani, Suresh; Samson, Leona D; Fox, James G