日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Controlled Self-Immolative Release of β-Lapachone via an Optimized para-Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy

通过优化的对羟基苄基连接基实现β-拉帕酮的可控自毁释放，用于靶向胰腺癌治疗

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c17598
Becher, Julie B; Dutta, Nisita; Navo, Claudio D; Dunsmore, Lavinia; Misteli, Roman; Gil de Montes, Enrique; Simpson, Grant G; Alewine, Christine C; Jiménez-Osés, Gonzalo; Bernardes, Gonçalo J L
胰腺癌
肿瘤
肿瘤免疫
发表日期：2025
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Gold(III)-Induced Amide Bond Cleavage In Vivo: A Dual Release Strategy via π-Acid Mediated Allyl Substitution

金(III)诱导的体内酰胺键断裂：通过π酸介导的烯丙基取代实现的双重释放策略

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c05582
Unnikrishnan, V B; Sabatino, Valerio; Amorim, Filipa; Estrada, Marta F; Navo, Claudio D; Jimenez-Oses, Gonzalo; Fior, Rita; Bernardes, Gonçalo J L
发表日期：2024
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Interplay of chloride levels and palladium(ii)-catalyzed O-deallenylation bioorthogonal uncaging reactions

氯离子浓度与钯(II)催化的O-脱烯丙基化生物正交脱笼反应的相互作用

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d3sc06408e
Dal Forno, Gean M; Latocheski, Eloah; Navo, Claudio D; Albuquerque, Brunno L; St John, Albert L; Avenier, Frédéric; Jiménez-Osés, Gonzalo; Domingos, Josiel B
发表日期：2024
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Highly Diastereoselective Multicomponent Synthesis of Spirocyclopropyl Oxindoles Enabled by Rare-Earth Metal Salts

稀土金属盐促进螺环丙基吲哚酮的高非对映选择性多组分合成

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.3c00772
Tallarida, Matteo A; Olivito, Fabrizio; Navo, Claudio D; Algieri, Vincenzo; Jiritano, Antonio; Costanzo, Paola; Poveda, Ana; Moure, Maria J; Jiménez-Barbero, Jesús; Maiuolo, Loredana; Jiménez-Osés, Gonzalo; De Nino, Antonio
发表日期：2023
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Experimental and Theoretical Analysis of the Thiol-Promoted Fragmentation of 2-Halo-3-tosyl-oxanorbornadienes

硫醇促进的2-卤代-3-甲苯磺酰基-氧杂降冰片二烯断裂的实验和理论分析

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.3c02548
Carranza, Marina; Carmona, Ana T; Navo, Claudio D; Robina, Inmaculada; Fratta, Simone; Newburn, Carlos; Jiménez-Osés, Gonzalo; Moreno-Vargas, Antonio J
发表日期：2023
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Synthesis of Fluorescent Lanthipeptide Cytolysin S Analogues by Late-Stage Sulfamidate Ring Opening

通过后期磺酰胺环开环合成荧光羊毛硫肽溶细胞素S类似物

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.3c00122
Mazo, Nuria; Rahman, Imran R; Navo, Claudio D; Peregrina, Jesús M; Busto, Jesús H; van der Donk, Wilfred A; Jiménez-Osés, Gonzalo
细胞生物学
IF
发表日期：2023
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Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination

通过 CC 键断裂 1,6-消除反应控制掩蔽和靶向释放氧化还原循环邻醌

期刊:Nature Chemistry
影响因子:19.2
doi:10.1038/s41557-022-00964-7
Lavinia Dunsmore, Claudio D Navo #, Julie Becher #, Enrique Gil de Montes #, Ana Guerreiro #, Emily Hoyt, Libby Brown, Viviane Zelenay, Sigitas Mikutis, Jonathan Cooper, Isaia Barbieri, Stefanie Lawrinowitz, Elise Siouve, Esther Martin, Pedro R Ruivo, Tiago Rodrigues, Filipa P da Cruz, Oliver Werz, 
信号转导
发表日期：2022
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

曲妥珠单抗上的单个突变会调节使用缩醛基连接子和硫醇-马来酰亚胺化学构建的抗体-药物偶联物的稳定性

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.1c07675
Ferhati, Xhenti; Jiménez-Moreno, Ester; Hoyt, Emily A; Salluce, Giulia; Cabeza-Cabrerizo, Mar; Navo, Claudio D; Compañón, Ismael; Akkapeddi, Padma; Matos, Maria J; Salaverri, Noelia; Garrido, Pablo; Martínez, Alfredo; Laserna, Víctor; Murray, Thomas V; Jiménez-Osés, Gonzalo; Ravn, Peter; Bernardes, Gonçalo J L; Corzana, Francisco
发表日期：2022
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Synthesis of β(2,2)-Amino Acids by Stereoselective Alkylation of Isoserine Derivatives Followed by Nucleophilic Ring Opening of Quaternary Sulfamidates

通过异丝氨酸衍生物的立体选择性烷基化和季铵盐的亲核开环反应合成β(2,2)-氨基酸

期刊:Journal of Organic Chemistry
影响因子:3.6
doi:10.1021/acs.joc.2c01034
Tovillas, Pablo; Navo, Claudio D; Oroz, Paula; Avenoza, Alberto; Corzana, Francisco; Zurbano, María M; Jiménez-Osés, Gonzalo; Busto, Jesús H; Peregrina, Jesús M
发表日期：2022
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Studies on the Regioselective Rearrangement of Azanorbornanic Aminyl Radicals into 2,8-Diazabicyclo[3.2.1]oct-2-ene Systems

对氮杂降冰片烷胺基自由基区域选择性重排为2,8-二氮杂双环[3.2.1]辛-2-烯体系的研究

期刊:Journal of Organic Chemistry
影响因子:3.6
doi:10.1021/acs.joc.2c02201
de Montes, Enrique Gil; Tallarida, Matteo A; Carmona, Ana T; Navo, Claudio D; Robina, Inmaculada; Elías-Rodríguez, Pilar; Jiménez-Osés, Gonzalo; Moreno-Vargas, Antonio J
发表日期：2022
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