Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients
新型 gRNA 设计流程,用于开发广谱 CRISPR/Cas9 gRNA,以安全靶向患者体内的 HIV-1 准物种
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-019-52353-9
Neil T Sullivan, Will Dampier, Cheng-Han Chung, Alexander G Allen, Andrew Atkins, Vanessa Pirrone, Greg Homan, Shendra Passic, Jean Williams, Wen Zhong, Katherine Kercher, Mathew Desimone, Luna Li, Gregory C Antell, Joshua Chang Mell, Garth D Ehrlich, Zsofia Szep, Jeffrey M Jacobson, Michael R Nonne