日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lysosomal phosphoinositide turnover acts upstream of RagGTPase-mTORC1 and controls muscle growth.

溶酶体磷脂酰肌醇周转作用于 RagGTPase-mTORC1 的上游,并控制肌肉生长。

Picot Melanie, Hifdi Nesrine, Vaucourt Mathilde, Mansat Melanie, Li Peng, Singer Isabel, Chicanne Gaëtan, Stella Alexandre, Kuang Shen, Miceli Caterina, Henneman Nathaniel F, Payrastre Bernard, Vandromme Marie, Schiltz Odile, Nemazanyy Ivan, de Araujo Mariana E G, Panasyuk Ganna, Viaud Julien, Lämmerhofer Michael, Hnia Karim

Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndrome

药物稳定缺氧诱导因子 1-α 可抑制干扰素反应并促进艾卡迪-古蒂埃综合征中的糖酵解。

Batignes, Maxime; Luka, Marine; Jagtap, Surabhi; de Cevins, Camille; Nemazanyy, Ivan; Leib, Jacqueline; Fali, Tinhinane; Pierga, Alexandre; Zarhrate, Mohammed; García-Paredes, Víctor; Carbone, Francesco; Pérot, Brieuc P; Neven, Bénédicte; Bader-Meunier, Brigitte; Quartier, Pierre; Hully, Marie; Belot, Alexandre; Lepelley, Alice; Frémond, Marie-Louise; Fischer, Alain; Ménager, Mickaël M

Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas.

L-天冬酰胺酶诱导的肿瘤代谢适应揭示了B细胞淋巴瘤对PARP1/2抑制剂的脆弱性。

Aussel Anaïs, Nemazanyy Ivan, Vandenberghe Ashaina, Meola Pauline, Dorat Noémie, Paul Rachel, Habbouche Lama, Exposito Laurie, Nottet Nicolas, Petrilli Virginie, Chiche Edmond, Mounier Nicolas, Marchetti Sandrine, Chaveroux Cédric, Ricci Jean-Ehrland, Chiche Johanna

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer.

STARD7 的缺失会引发乳腺癌的代谢重编程和细胞周期停滞

Dondajewska Ewelina, Allepuz-Fuster Paula, Maurizy Chloé, Hego Alexandre, Ormenese Sandra, Lion Quentin, Blomme Arnaud, Close Pierre, Lavergne Arnaud, Karim Latifa, Thiry Marc, Nemazanyy Ivan, Krishnankutty Roopesh, Marques Jair Jr, von Kriegsheim Alex, Henneman Nathaniel F, Panasyuk Ganna, Shostak Kateryna, Chariot Alain

Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions

脂肪细胞特异性Mlkl敲除通过增强线粒体功能减轻肥胖引起的代谢功能障碍

Tokgozoglu, Juliette; Pistorio, Valeria; Minini, Mirko; Soret, Pierre-Antoine; Steunou, Virginie; Delaunay, Jean-Louis; Castel, Julien; Luquet, Serge; Nemazanyy, Ivan; Beaupère, Carine; Dinard, Laetitia; Ledent, Tatiana; L'honoré, Aurore; Lemoinne, Sara; Housset, Chantal; Lesnik, Philippe; Ratziu, Vlad; Fève, Bruno; Aït-Slimane, Tounsia; Cadoret, Axelle; Chignard, Nicolas; Gautheron, Jérémie

mTOR controls ependymal cell differentiation by targeting the alternative cell cycle and centrosomal proteins.

mTOR 通过靶向替代细胞周期和中心体蛋白来控制室管膜细胞分化

Bankolé Alexia, Srivastava Ayush, Shihavuddin Asm, Tighanimine Khaled, Faucourt Marion, Koka Vonda, Weill Solene, Nemazanyy Ivan, Nelson Alissa J, Stokes Matthew P, Delgehyr Nathalie, Genovesio Auguste, Meunier Alice, Fumagalli Stefano, Pende Mario, Spassky Nathalie

Interferon gamma induced-ACSL5 shapes the lipidome of kidney tubular cells.

干扰素γ诱导的ACSL5塑造肾小管细胞的脂质组

Poindessous Virginie, Sampaio Julio L, Bouidghaghen Lydia, Nemazanyy Ivan, Pallet Alexandre, Naesens Maarten, Vaulet Thibaut, Anglicheau Dany, Pallet Nicolas

G-quadruplex ligand RHPS4 compromises cellular radioresistance by inhibiting the mitochondrial adaptive response induced by ionizing irradiation

G-四链体配体RHPS4通过抑制电离辐射诱导的线粒体适应性反应来削弱细胞的放射抗性。

Tricot, Sabine; Siberchicot, Capucine; Bontemps, Isaline; Desmaze, Chantal; Kratassiouk, Gueorgui; Vandamme, Marie; Pinna, Guillaume; Nemazanyy, Ivan; Radicella, J Pablo; Lenaers, Guy; Renaudin, Xavier; Lebeau, Jérome; Campalans, Anna

A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules

哺乳动物翻译因子eEF1A的A2亚型表现出酪氨酸磷酸化水平升高,并能与不同的信号分子相互作用。

Panasyuk, Ganna; Nemazanyy, Ivan; Filonenko, Valeriy; Negrutskii, Boris; El'skaya, Anna V