日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA

杀稻瘟菌素 S 抑制哺乳动物翻译并增强无义 mRNA 编码蛋白质的产生

Kyle T Powers, Flint Stevenson-Jones, Sathish K N Yadav, Beate Amthor, Joshua C Bufton, Ufuk Borucu, Dakang Shen, Jonas P Becker, Daria Lavysh, Matthias W Hentze, Andreas E Kulozik, Gabriele Neu-Yilik, Christiane Schaffitzel

NMD inhibition by 5-azacytidine augments presentation of immunogenic frameshift-derived neoepitopes

5-氮胞苷通过抑制NMD增强免疫原性移码衍生新表位的呈递

Becker, Jonas P; Helm, Dominic; Rettel, Mandy; Stein, Frank; Hernandez-Sanchez, Alejandro; Urban, Katharina; Gebert, Johannes; Kloor, Matthias; Neu-Yilik, Gabriele; von Knebel Doeberitz, Magnus; Hentze, Matthias W; Kulozik, Andreas E

Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins

RNA结合蛋白的核质应激反应的可塑性

Michael Backlund ,Frank Stein ,Mandy Rettel ,Thomas Schwarzl ,Joel I Perez-Perri ,Annika Brosig ,Yang Zhou ,Gabriele Neu-Yilik ,Matthias W Hentze ,Andreas E Kulozik

Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient-derived osteosarcoma cells and synergizes with cisplatin and talazoparib

Prexasertib (LY2606368) 通过诱导患者原发性骨肉瘤细胞凋亡来降低克隆形成存活率,并与顺铂和他拉唑帕尼产生协同作用

Christopher L Heidler, Eva K Roth, Markus Thiemann, Claudia Blattmann, Ramon L Perez, Peter E Huber, Michal Kovac, Beate Amthor, Gabriele Neu-Yilik, Andreas E Kulozik

UPF1-Mediated RNA Decay-Danse Macabre in a Cloud

UPF1介导的RNA衰变——云中死亡之舞

Lavysh, Daria; Neu-Yilik, Gabriele

(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A

微卫星不稳定 CRC 细胞的 (磷酸化) 蛋白质组学分析揭示了 NMD 调节器 UPF3A 的移码突变引起的核信号和胆固醇代谢的改变

Malwina Michalak, Eva-Maria Katzenmaier, Nina Roeckel, Stefan M Woerner, Vera Fuchs, Uwe Warnken, Yan P Yuan, Peer Bork, Gabriele Neu-Yilik, Andreas Kulozik, Magnus von Knebel Doeberitz, Matthias Kloor, Jürgen Kopitz, Johannes Gebert

Dual function of UPF3B in early and late translation termination

UPF3B 在早期和晚期翻译终止中的双重功能

Gabriele Neu-Yilik, Etienne Raimondeau, Boris Eliseev, Lahari Yeramala, Beate Amthor, Aurélien Deniaud, Karine Huard, Kathrin Kerschgens, Matthias W Hentze, Christiane Schaffitzel, Andreas E Kulozik

Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay

蛋白质组学分析揭示无义介导的 mRNA 衰变对未折叠蛋白质反应的分支特异性调控

Jana Sieber, Christian Hauer, Madhuri Bhuvanagiri, Stefan Leicht, Jeroen Krijgsveld, Gabriele Neu-Yilik, Matthias W Hentze, Andreas E Kulozik

The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion

选择性多聚腺苷酸化转录本的差异表达是一种常见的应激诱导反应机制,它以数量和质量的方式调节哺乳动物mRNA的表达。

Hollerer, Ina; Curk, Tomaz; Haase, Bettina; Benes, Vladimir; Hauer, Christian; Neu-Yilik, Gabriele; Bhuvanagiri, Madhuri; Hentze, Matthias W; Kulozik, Andreas E

A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation

SMG-8、SMG-9 和 SMG-1 C 端插入域网络调节 UPF1 底物募集和磷酸化

Aurélien Deniaud, Manikandan Karuppasamy, Thomas Bock, Simonas Masiulis, Karine Huard, Frédéric Garzoni, Kathrin Kerschgens, Matthias W Hentze, Andreas E Kulozik, Martin Beck, Gabriele Neu-Yilik, Christiane Schaffitzel