Discovery and Characterization of Divarasib (GDC-6036), a Potent Covalent Inhibitor of KRAS G12C.
Divarasib (GDC-6036) 的发现和表征，一种强效的 KRAS G12C 共价抑制剂。
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02272
Endres Nicholas F, Do Steven, Mroue Rana, Terrett Jack A, Saabye Matt, Oh Angela, Hunsaker Thomas, Chan Emily, Tran John C, Nguyen Lan K, Lian Qihui, Ma Taylur P, Garner Thomas, Gerosa Luca, Beresini Maureen, Boudreau Aaron, Bronner Sarah M, Cyr Patrick, Ishisoko Noriko, Izrayelit Yevgeniy, Jiang Fan, Kellar Terry, La Hank, Labadie Sharada, Lardy Matthew, Liu Liling, Liu Wendy, Miller Sarah, Rudolph Joachim, Plise Emile, Sellers Benjamin D, Shao Cheng, Wang Weiru, Wang Yanguang, Wei Wentao, Wong Susan, Yu Christine, Yu Kebing, Yuen Po-Wai, Zang Richard, Zhang Chenghong, Zhou Yuhui, Zhu Xiaoyu, Quinn John G, Ye Xin, Kiefer James R, Mao Jialin, Evangelista Marie, Merchant Mark, Landry Matthew L, Malhotra Sushant, Purkey Hans E
