Nguyen MyTrang相关文献与解析，生知库 | 链接生命科学的每一步

Mice humanized by syntenic replacement with full-length NLRP3 disease-associated variants model the clinical cryopyrinopathy continuum

通过将全长NLRP3疾病相关变异体进行同源替换而人源化的小鼠模型模拟了临床冷吡啉病连续谱。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.194677

Snouwaert, John N; Nguyen, MyTrang; Gabel, Christopher A; Aksentijevich, Ivona; Ting, Jenny P-Y; Koller, Beverly H

Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework.

在细胞和小鼠炎症模型中对 NLRP3 炎症小体抑制剂钠 [(1,2,3,5,6,7-六氢-s-茚满-4-基)氨基甲酰基][(1-甲基-1H-吡唑-4-基)({[(2S)-氧杂环戊烷-2-基]甲基})磺酰胺酰基]氮化物进行药理学分析，为转化应用提供了框架

期刊:ACS Pharmacology and Translational Science

影响因子:3.7

doi:10.1021/acsptsci.4c00061

Doedens John R, Smolak Pamela, Nguyen MyTrang, Wescott Heather, Diamond Christine, Schooley Ken, Billinton Andy, Harrison David, Koller Beverly H, Watt Alan P, Gabel Christopher A

Mice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families

缺失编码14个谷胱甘肽转移酶基因的三个基因座的小鼠：一种用于确定GSTP、GSTM和GSTT家族功能的新工具

期刊:Drug Metabolism and Disposition

影响因子:4

doi:10.1124/dmd.113.056481

Xiang, Zhidan; Snouwaert, John N; Kovarova, Martina; Nguyen, Mytrang; Repenning, Peter W; Latour, Anne M; Cyphert, Jaime M; Koller, Beverly H

发表日期：2014

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ONZIN deficiency attenuates contact hypersensitivity responses in mice

ONZIN 缺乏会减弱小鼠的接触性超敏反应。

期刊:Immunology and Cell Biology

影响因子:3

doi:10.1038/icb.2011.107

Ledford, Julie G; Kovarova, Martina; Jania, Leigh A; Nguyen, Mytrang; Koller, Beverly H

发表日期：2012

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Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1Î² levels.

小鼠 pyrin（家族性地中海热蛋白）的基因缺失会增加白细胞介素-1β 水平

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0051105

Hesker Pamela R, Nguyen MyTrang, Kovarova Martina, Ting Jenny P-Y, Koller Beverly H

细胞生物学

发表日期：2012

文献求助收藏

PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth

PGE2 通过 EP4 受体调控动脉导管平滑肌基因表达模式，这对于出生时的重塑至关重要。

期刊:Prostaglandins & Other Lipid Mediators

影响因子:2.5

doi:10.1016/j.prostaglandins.2012.02.001

Gruzdev, Artiom; Nguyen, MyTrang; Kovarova, Martina; Koller, Beverly H

信号转导

发表日期：2012

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购买 Syk，开始骑行

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.20020422195907cor

发表日期：2006

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CNS-targeted NLRP3 Inhibition by NT-0527 confers therapeutic advantage in a CAPS mouse model.

NT-0527 对 CNS 靶向 NLRP3 的抑制作用在 CAPS 小鼠模型中具有治疗优势。

Mice humanized by syntenic replacement with full-length NLRP3 disease-associated variants model the clinical cryopyrinopathy continuum

通过将全长NLRP3疾病相关变异体进行同源替换而人源化的小鼠模型模拟了临床冷吡啉病连续谱。

Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework.

在细胞和小鼠炎症模型中对 NLRP3 炎症小体抑制剂钠 [(1,2,3,5,6,7-六氢-s-茚满-4-基)氨基甲酰基][(1-甲基-1H-吡唑-4-基)({[(2S)-氧杂环戊烷-2-基]甲基})磺酰胺酰基]氮化物进行药理学分析，为转化应用提供了框架

Mice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families

缺失编码14个谷胱甘肽转移酶基因的三个基因座的小鼠：一种用于确定GSTP、GSTM和GSTT家族功能的新工具

ONZIN deficiency attenuates contact hypersensitivity responses in mice

ONZIN 缺乏会减弱小鼠的接触性超敏反应。

Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1Î² levels.

小鼠 pyrin（家族性地中海热蛋白）的基因缺失会增加白细胞介素-1β 水平

PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth

PGE2 通过 EP4 受体调控动脉导管平滑肌基因表达模式，这对于出生时的重塑至关重要。

Get Syk and get cycling

购买 Syk，开始骑行