日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition

2-苯基喹啉类化合物通过抑制非结构蛋白13解旋酶发挥抗严重急性呼吸综合征冠状病毒2活性

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.202501063
Cernicchi, Giada; Nizi, Maria Giulia; Emmolo, Roberta; Persoons, Leentje; Laporte, Manon; Jochmans, Dirk; Romeo, Isabella; Pepe, Giacomo; Milite, Ciro; Campiglia, Pietro; Spezzini, Jacopo; Martelli, Alma; Brogi, Simone; Esposito, Francesca; Felicetti, Tommaso; Massari, Serena; Manfroni, Giuseppe; Sabatini, Stefano; Sbardella, Gianluca; Alcaro, Stefano; Neyts, Johan; Corona, Angela; Tramontano, Enzo; De Jonghe, Steven; Tabarrini, Oriana
微生物学
发表日期：2026
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Synthetically accessible de novo design using reaction vectors: Application to PARP1 inhibitors

利用反应载体进行合成可及的从头设计：应用于PARP1抑制剂

期刊:Molecular Informatics
影响因子:3.1
doi:10.1002/minf.202300183
Ghiandoni, Gian Marco; Flanagan, Stuart R; Bodkin, Michael J; Nizi, Maria Giulia; Galera-Prat, Albert; Brai, Annalaura; Chen, Beining; Wallace, James E A; Hristozov, Dimitar; Webster, James; Manfroni, Giuseppe; Lehtiö, Lari; Tabarrini, Oriana; Gillet, Valerie J
PARP
PARP1
发表日期：2024
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[1,2,4]Triazolo[3,4- b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes

[1,2,4]三唑并[3,4-b]苯并噻唑支架作为多功能烟酰胺模拟物，可对不同的 PARP 酶进行纳摩尔级抑制

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.2c01460
Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, L
PARP
发表日期：2023
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Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules

从药物化学角度探讨小分子靶向单ADP核糖基化PARP的策略

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.2c00281
Nizi, Maria Giulia; Maksimainen, Mirko M; Lehtiö, Lari; Tabarrini, Oriana
PARP
发表日期：2022
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Inhibition of Influenza Virus Polymerase by Interfering with Its Protein-Protein Interactions

通过干扰蛋白质-蛋白质相互作用抑制流感病毒聚合酶

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.0c00552
Massari, Serena; Desantis, Jenny; Nizi, Maria Giulia; Cecchetti, Violetta; Tabarrini, Oriana
微生物学
流感
发表日期：2021
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Mabs for treating asthma: omalizumab, mepolizumab, reslizumab, benralizumab, dupilumab

用于治疗哮喘的单克隆抗体：omalizumab、mepolizumab、reslizumab、benralizumab、dupilumab

期刊:Human Vaccines & Immunotherapeutics
影响因子:3.5
doi:10.1080/21645515.2020.1753440
Ridolo, Erminia; Pucciarini, Francesco; Nizi, Maria Cristina; Makri, Eleni; Kihlgren, Paola; Panella, Lorenzo; Incorvaia, Cristoforo
单克隆抗体
哮喘
发表日期：2020
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Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides

改良型选择性I类HDAC抑制剂和新型选择性HDAC3抑制剂：超越羟肟酸和苯甲酰胺

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.8b00517
Bresciani, Alberto; Ontoria, Jesus M; Biancofiore, Ilaria; Cellucci, Antonella; Ciammaichella, Alina; Di Marco, Annalise; Ferrigno, Federica; Francone, Alessandra; Malancona, Savina; Monteagudo, Edith; Nizi, Emanuela; Pace, Paola; Ponzi, Simona; Rossetti, Ilaria; Veneziano, Maria; Summa, Vincenzo; Harper, Steven
HDAC3
发表日期：2019
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Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

鉴定新型多阶段组蛋白去乙酰化酶 (HDAC) 抑制剂，以削弱曼氏血吸虫的生存能力和产卵量

期刊:Parasites & Vectors
影响因子:3
doi:10.1186/s13071-018-3268-8
Alessandra Guidi, Fulvio Saccoccia, Nadia Gennari, Roberto Gimmelli, Emanuela Nizi, Cristiana Lalli, Giacomo Paonessa, Giuliana Papoff, Alberto Bresciani, Giovina Ruberti
表观遗传
发表日期：2018
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Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production

通过基于生物体的高通量筛选，发现影响曼氏血吸虫活力、卵形成和生产的新型多阶段化合物。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0005994
Guidi, Alessandra; Lalli, Cristiana; Gimmelli, Roberto; Nizi, Emanuela; Andreini, Matteo; Gennari, Nadia; Saccoccia, Fulvio; Harper, Steven; Bresciani, Alberto; Ruberti, Giovina
发表日期：2017
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Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs

发现一系列选择性抑制恶性疟原虫 HDAC 的抑制剂

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5b00468
Ontoria, Jesus M; Paonessa, Giacomo; Ponzi, Simona; Ferrigno, Federica; Nizi, Emanuela; Biancofiore, Ilaria; Malancona, Savina; Graziani, Rita; Roberts, David; Willis, Paul; Bresciani, Alberto; Gennari, Nadia; Cecchetti, Ottavia; Monteagudo, Edith; Orsale, Maria V; Veneziano, Maria; Di Marco, Annalise; Cellucci, Antonella; Laufer, Ralph; Altamura, Sergio; Summa, Vincenzo; Harper, Steven
发表日期：2016
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