日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

NSD2 upregulation is driven by high-risk HPV E6/E7 and disrupts epithelial differentiation in HPV-associated head and neck cancer

NSD2 上调是由高危型 HPV E6/E7 驱动的，并会破坏 HPV 相关头颈癌中的上皮分化。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03631-0
Ghiani, Lavinia; Citro, Simona; Medda, Alessandro; Doni, Mirko; Ghoryani, Farkhondeh; Noberini, Roberta; Croci, Ottavio; Maffini, Fausto; Miccolo, Claudia; Monteleone, Laura; Tagliabue, Marta; De Berardinis, Rita; Campaner, Stefano; Bonaldi, Tiziana; Ansarin, Mohssen; Chiocca, Susanna
肿瘤
肿瘤免疫
NSD2
头颈癌
发表日期：2026
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Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression

哺乳动物H4K16ac调控基因组复制的时空顺序，而非基因表达。

期刊:Nucleic Acids Research
影响因子:16.6
doi:10.1093/nar/gkaf916.
Marta Milan ,Valeria Runfola ,Manthan Patel ,Lucia Falbo ,Roberta Noberini ,Chiara Soriani ,Simona Rodighiero ,Tiziana Bonaldi ,Vincenzo Costanzo ,Madapura M Pradeepa ,Paola Scaffidi
信号转导
NK细胞
发表日期：2025
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Systematic genetic perturbation reveals principles underpinning robustness of the epigenetic regulatory network

系统性的基因扰动揭示了表观遗传调控网络稳健性的潜在原理

期刊:Nucleic Acids Research
影响因子:16.6
doi:10.1093/nar/gkaf297
Thomas Stuart Wilson ,Roberta Noberini ,Eirini Moysidou ,Ifeyinwa Ojukwu ,Marta Milan ,Ming Jiang ,Gavin Kelly ,Michael Howell ,Tiziana Bonaldi ,Paola Scaffidi
信号转导
表观遗传
发表日期：2025
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A histone-centric multi-omics study shows that increased H3K4 methylation sustains triple-negative breast cancer phenotypes.

一项以组蛋白为中心的多组学研究表明，H3K4 甲基化增加可维持三阴性乳腺癌表型。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63745-z
Noberini Roberta, Robusti Giulia, Vai Alessandro, Savoia Evelyn Oliva, Jodice Maria Giovanna, Bertalot Giovanni, Çat Betül, Pallavicini Isabella, Bonizzi Giuseppina, Capra Maria, Sangalli Claudia Anna, Zambelli Federico, Fusco Nicola, Pece Salvatore, Pavesi Giulio, Minucci Saverio, Bonaldi Tiziana
乳腺癌
心血管
发表日期：2025
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Metabolic traits shape responses to LSD1-directed therapy in glioblastoma tumor-initiating cells

代谢特征影响胶质母细胞瘤肿瘤起始细胞对LSD1靶向治疗的反应

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adt2724
Marotta, Giulia; Osti, Daniela; Zaccheroni, Elena; Costanza, Brunella; Faletti, Stefania; Marinaro, Adriana; Richichi, Cristina; Mesa, Deborah; Rodighiero, Simona; Soriani, Chiara; Migliaccio, Enrica; Ruscitto, Federica; Priami, Chiara; Sigismund, Sara; Manetti, Francesco; Polli, Dario; Beznusenko, Galina V; Rusu, Mara-Camelia; Favero, Francesco; Corà, Davide; Silvestris, Domenico A; Gallo, Angela; Gambino, Valentina; Alfieri, Fabio; Gandini, Sara; Schmitt, Matthias J; Gargiulo, Gaetano; Noberini, Roberta; Bonaldi, Tiziana; Pelicci, Giuliana
肿瘤
肿瘤免疫
LSD1
代谢
细胞生物学
发表日期：2025
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Age-associated metabolic and epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes

小鼠成纤维细胞直接重编程为诱导心肌细胞过程中与年龄相关的代谢和表观遗传障碍

期刊:Aging Cell
影响因子:8
doi:10.1111/acel.14371
Francisco Santos, Magda Correia, Rafaela Dias, Bárbara Bola, Roberta Noberini, Rita S Ferreira, Diogo Trigo, Pedro Domingues, José Teixeira, Tiziana Bonaldi, Paulo J Oliveira, Christian Bär, Bruno Bernardes de Jesus, Sandrina Nóbrega-Pereira
代谢
表观遗传
成纤维细胞
发表日期：2025
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Correction: HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy

更正：ITF3756 通过抑制 HDAC6 来调节 PD-L1 表达和单核细胞表型：为有前景的免疫检查点阻断联合治疗提供启示

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1645773
Spadotto, Valeria; Ripamonti, Chiara; Ghiroldi, Andrea; Galbiati, Elisabetta; Pozzi, Pietro; Noberini, Roberta; Bonaldi, Tiziana; Steinkühler, Christian; Fossati, Gianluca
PD-L1
单核细胞
细胞生物学
HDAC6
免疫/内分泌
发表日期：2025
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HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy

ITF3756 通过抑制 HDAC6 来调节 PD-L1 表达和单核细胞表型：为一种有前景的免疫检查点阻断联合治疗方案提供新的见解

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2025.1546939
Valeria Spadotto # ,Chiara Ripamonti # ,Andrea Ghiroldi ,Elisabetta Galbiati ,Pietro Pozzi ,Roberta Noberini ,Tiziana Bonaldi ,Christian Steinkühler ,Gianluca Fossati
PD-L1
单核细胞
细胞生物学
HDAC6
免疫/内分泌
发表日期：2025
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Breaking Boundaries in Histone Modification MS-Based Detection: A Tailored Search Strategy for Unrestricted Identification of Novel Epigenetic Marks

突破组蛋白修饰质谱检测的界限：一种用于无限制鉴定新型表观遗传标记的定制搜索策略

期刊:Molecular & Cellular Proteomics
影响因子:5.5
doi:10.1016/j.mcpro.2025.101080
Vai, Alessandro; Noberini, Roberta; Graziadei, Andrea; Polasky, Daniel A; Yu, Fengchao; Nesvizhskii, Alexey I; Bonaldi, Tiziana
组蛋白修饰
表观遗传
发表日期：2025
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H2A.X N-terminal acetylation is a newly identified NAA40-mediated modification that is responsive to UV irradiation.

H2A.X N 端乙酰化是一种新发现的 NAA40 介导的修饰，可响应紫外线照射

期刊:Epigenetics & Chromatin
影响因子:3.5
doi:10.1186/s13072-025-00608-3
Klavaris Ariel, Koufaris Costas, Noberini Roberta, Kouma Maria, Demetriadou Christina, Ghiringhelli Alessandro, Dietis Nikolas, Bonaldi Tiziana, Kirmizis Antonis
其它
乙酰化
发表日期：2025
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