日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Harnessing Substituted 4-Chlorothieno[2,3-b]pyridine as a New Cap for Potent and Selective Antiproliferative HDAC Inhibitors

利用取代的4-氯噻吩并[2,3-b]吡啶作为新型帽结构开发高效选择性抗增殖HDAC抑制剂

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph19030442
Badran, Mostafa M; Beyri, Berkay; Tateishi, Hiroshi; Shimagaki, Kazunori; Nakata, Akiko; Ito, Akihiro; Nishimura, Nao; Abbas, Samar H; Abdel-Aziz, Mohamed; Otsuka, Masami; Yoshida, Minoru; Fujita, Mikako; Bräse, Stefan; Radwan, Mohamed O
发表日期：2026
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Design, Synthesis, and Anticancer Evaluation of New Small-Molecule EGFR Inhibitors Targeting NSCLC and Breast Cancer.

针对非小细胞肺癌和乳腺癌的新型小分子 EGFR 抑制剂的设计、合成和抗癌评价

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26157065
Sever Belgin, Otsuka Masami, Fujita Mikako, Ciftci Halilibrahim
细胞生物学
乳腺癌
肺癌
EGFR
发表日期：2025
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Hydrazonylthiazole Derivatives as Dual EGFR and ALR2 Inhibitors: Design, Synthesis, and Comprehensive In Vitro and In Silico Evaluation for Potential Anticancer Activity

肼基噻唑衍生物作为双重EGFR和ALR2抑制剂：设计、合成及体外和计算机模拟抗癌活性综合评价

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph19010050
Sever, Belgin; Türkeş, Cüneyt; Demir, Yeliz; Elamin, Khaled M; Osman, Wadah; Oral, Kübra; Akıncı Genç, Selenay; Cantürk, Zerrin; Masunaga, Takuya; Kishimoto, Naoki; Misumi, Shogo; Otsuka, Masami; Fujita, Mikako; Ciftci, Halilibrahim
肿瘤
肿瘤免疫
EGF
ALR
EGFR
发表日期：2025
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A Structural Insight Into Two Important ErbB Receptors (EGFR and HER2) and Their Relevance to Non-Small Cell Lung Cancer

对两种重要的ErbB受体（EGFR和HER2）的结构解析及其与非小细胞肺癌的相关性

期刊:Archiv der Pharmazie
影响因子:3.6
doi:10.1002/ardp.202400992
Topalan, Edanur; Büyükgüngör, Ahmet; Çiğdem, Melih; Güra, Sinan; Sever, Belgin; Otsuka, Masami; Fujita, Mikako; Demirci, Hasan; Ciftci, Halilibrahim
肺癌
肿瘤
HER2
肿瘤免疫
信号转导
EGF
EGFR
细胞生物学
发表日期：2025
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Structure and Dynamics of the ABL1 Tyrosine Kinase and Its Important Role in Chronic Myeloid Leukemia

ABL1酪氨酸激酶的结构和动力学及其在慢性粒细胞白血病中的重要作用

期刊:Archiv der Pharmazie
影响因子:3.6
doi:10.1002/ardp.70005
Irgit, Ayca; Kamıs, Reyhan; Sever, Belgin; Tuyun, Amaç Fatih; Otsuka, Masami; Fujita, Mikako; Demirci, Hasan; Ciftci, Halilibrahim
信号转导
ABL1
粒细胞
白血病
细胞生物学
发表日期：2025
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Insights into therapeutic discovery through the Kelch domain structure of Keap1 at ambient temperature

室温下Keap1的Kelch结构域结构对治疗发现的启示

期刊:
影响因子:
doi:10.55730/1300-0152.2742
Yilmaz, Merve; Sever, Belgin; Kutlu, Yiğit; Gül, Mehmet; Okuducu, Ceren; Tavli, Serra; Otsuka, Masami; Fujita, Mikako; Haliloğlu, Türkan; Çiftçi, Halilibrahim; Demirci, Hasan
发表日期：2025
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A Review of FDA-Approved Anti-HIV-1 Drugs, Anti-Gag Compounds, and Potential Strategies for HIV-1 Eradication

对FDA批准的抗HIV-1药物、抗GAG化合物以及HIV-1根除潜在策略的综述

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms25073659
Sever, Belgin; Otsuka, Masami; Fujita, Mikako; Ciftci, Halilibrahim
HIV
微生物学
发表日期：2024
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Structural Characterization of TRAF6 N-Terminal for Therapeutic Uses and Computational Studies on New Derivatives

TRAF6 N端结构表征及其在治疗应用中的研究及新型衍生物的计算研究

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph16111608
Guven, Omur; Sever, Belgin; Başoğlu-Ünal, Faika; Ece, Abdulilah; Tateishi, Hiroshi; Koga, Ryoko; Radwan, Mohamed O; Demir, Nefise; Can, Mustafa; Dilsiz Aytemir, Mutlu; Inoue, Jun-Ichiro; Otsuka, Masami; Fujita, Mikako; Ciftci, Halilibrahim; DeMirci, Hasan
TRAF6
发表日期：2023
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Harnessing Oleanolic Acid and Its Derivatives as Modulators of Metabolic Nuclear Receptors

利用齐墩果酸及其衍生物作为代谢核受体的调节剂

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom13101465
Radwan, Mohamed O; Kadasah, Sultan F; Aljubiri, Salha M; Alrefaei, Abdulmajeed F; El-Maghrabey, Mahmoud H; El Hamd, Mohamed A; Tateishi, Hiroshi; Otsuka, Masami; Fujita, Mikako
信号转导
代谢
发表日期：2023
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Gypsogenin Battling for a Front Position in the Pentacyclic Triterpenes Game of Thrones on Anti-Cancer Therapy: A Critical Review-Dedicated to the Memory of Professor Hanaa M. Rady

石竹皂苷元在五环三萜类化合物抗癌治疗领域争夺领先地位：一篇重要的综述——谨以此文纪念哈娜·M·拉迪教授

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28155677
Radwan, Mohamed O; Abd-Alla, Howaida I; Alsaggaf, Azhaar T; El-Mezayen, Hatem; Abourehab, Mohammed A S; El-Beeh, Mohamed E; Tateishi, Hiroshi; Otsuka, Masami; Fujita, Mikako
肿瘤
肿瘤免疫
发表日期：2023
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