日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PGC-1α functions as a co-suppressor of XBP1s to regulate glucose metabolism

PGC-1α 作为 XBP1s 的共抑制因子,调节葡萄糖代谢。

Lee, Jaemin; Salazar Hernández, Mario Andrés; Auen, Thomas; Mucka, Patrick; Lee, Justin; Ozcan, Umut

XBP1s Is an Anti-lipogenic Protein

XBP1s是一种抗脂肪生成蛋白

Herrema, Hilde; Zhou, Yingjiang; Zhang, Dongyan; Lee, Justin; Salazar Hernandez, Mario Andres; Shulman, Gerald I; Ozcan, Umut

Treatment of obesity with celastrol

用雷公藤内酯醇治疗肥胖症

Liu, Junli; Lee, Jaemin; Salazar Hernandez, Mario Andres; Mazitschek, Ralph; Ozcan, Umut

Unfolded protein response signaling and metabolic diseases

未折叠蛋白反应信号传导与代谢疾病

Lee, Jaemin; Ozcan, Umut

Potential for therapeutic manipulation of the UPR in disease

疾病中UPR的治疗调控潜力

Park, Sang Won; Ozcan, Umut

Epinephrine deficiency results in intact glucose counter-regulation, severe hepatic steatosis and possible defective autophagy in fasting mice

肾上腺素缺乏会导致禁食小鼠的葡萄糖反调节功能正常、出现严重的肝脂肪变性,并可能伴有自噬缺陷。

Sharara-Chami, Rana I; Zhou, Yingjiang; Ebert, Steven; Pacak, Karel; Ozcan, Umut; Majzoub, Joseph A

Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

通过 XBP-1-FoxO1 相互作用调节葡萄糖稳态

Zhou, Yingjiang; Lee, Justin; Reno, Candace M; Sun, Cheng; Park, Sang Won; Chung, Jason; Lee, Jaemin; Fisher, Simon J; White, Morris F; Biddinger, Sudha B; Ozcan, Umut

p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis

p38 MAPK介导的Xbp1s调控对葡萄糖稳态至关重要

Lee, Jaemin; Sun, Cheng; Zhou, Yingjiang; Lee, Justin; Gokalp, Deniz; Herrema, Hilde; Park, Sang Won; Davis, Roger J; Ozcan, Umut

The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation.

PI3K 的调节亚基 p85α 和 p85β 与 XBP-1 相互作用,并增加其核转位

Park Sang Won, Zhou Yingjiang, Lee Justin, Lu Allen, Sun Cheng, Chung Jason, Ueki Kohjiro, Ozcan Umut