日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Adeno-Associated Virus 8 and 9 Myofibre Type/Size Tropism Profiling Reveals Therapeutic Effect of Microdystrophin in Canines

腺相关病毒8型和9型肌纤维类型/大小嗜性分析揭示了微型肌营养不良蛋白在犬类中的治疗效果

Burke, Matthew J; Blatt, Braiden M; Teixeira, James A; Pérez-López, Dennis O; Yue, Yongping; Pan, Xiufang; Hakim, Chady H; Yao, Gang; Herzog, Roland W; Duan, Dongsheng

DWORF expression is reduced in a large animal model of Duchenne muscular dystrophy

在杜氏肌营养不良症的大动物模型中,DWORF表达降低。

Gibson, Aaron M; Pan, Xiufang; Brito-Estrada, Omar; Teixeira, James A; Carl, Lauren K; Yue, Yongping; Kamradt, Michael L; Burke, Matthew J; Wadding-Lee, Caris A; Yao, Gang; Herzog, Roland W; Duan, Dongsheng; Makarewich, Catherine A

Genetic reduction of skeletal muscle glycogen synthase 1 abundance reveals that the refeeding-induced reversal of elevated insulin-stimulated glucose uptake after exercise is not attributable to achieving a high muscle glycogen concentration.

骨骼肌糖原合成酶 1 丰度的基因减少表明,运动后重新进食引起的胰岛素刺激葡萄糖摄取增加的逆转,并非由于肌肉糖原浓度升高所致

Kwak Seong Eun, Wang Haiyan, Pan Xiufang, Duan Dongsheng, Cartee Gregory D

Phosphorylation of AS160-serine 704 is not essential for exercise-increase in insulin-stimulated glucose uptake by skeletal muscles from female or male rats.

AS160-丝氨酸704的磷酸化对于雌性或雄性大鼠骨骼肌胰岛素刺激的葡萄糖摄取增加并非必需

Wang Haiyan, Kwak Seong Eun, Zheng Amy, Arias Edward B, Pan Xiufang, Duan Dongsheng, Cartee Gregory D

Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy

在杜氏肌营养不良症GRMD模型中评估全身性AAV-微型肌营养不良蛋白基因治疗

Birch, Sharla M; Lawlor, Michael W; Conlon, Thomas J; Guo, Lee-Jae; Crudele, Julie M; Hawkins, Eleanor C; Nghiem, Peter P; Ahn, Mihye; Meng, Hui; Beatka, Margaret J; Fickau, Brittany A; Prieto, Juan C; Styner, Martin A; Struharik, Michael J; Shanks, Courtney; Brown, Kristy J; Golebiowski, Diane; Bettis, Amanda K; Balog-Alvarez, Cynthia J; Clement, Nathalie; Coleman, Kirsten E; Corti, Manuela; Pan, Xiufang; Hauschka, Stephen D; Gonzalez, J Patrick; Morris, Carl A; Schneider, Joel S; Duan, Dongsheng; Chamberlain, Jeffrey S; Byrne, Barry J; Kornegay, Joe N

AS160 expression, but not AS160 Serine-588, Threonine-642, and Serine-704 phosphorylation, is essential for elevated insulin-stimulated glucose uptake by skeletal muscle from female rats after acute exercise.

AS160 的表达,而不是 AS160 丝氨酸-588、苏氨酸-642 和丝氨酸-704 的磷酸化,对于雌性大鼠急性运动后骨骼肌胰岛素刺激的葡萄糖摄取增加至关重要

Wang Haiyan, Zheng Amy, Arias Edward B, Kwak Seong Eun, Pan Xiufang, Duan Dongsheng, Cartee Gregory D

Microdystrophin Therapy Rescues Impaired Na Currents in Cardiac Purkinje Fibers From Dystrophin-Deficient Mdx Mice

微型肌营养不良蛋白疗法可挽救肌营养不良蛋白缺陷型 Mdx 小鼠心脏浦肯野纤维中受损的钠电流

Ebner, Janine; Pan, Xiufang; Yue, Yongping; Sideromenos, Spyridon; Marksteiner, Jessica; Koenig, Xaver; Hilber, Karlheinz; Duan, Dongsheng

FBXW7 inactivation induces cellular senescence via accumulation of p53

FBXW7失活通过p53的积累诱导细胞衰老

Longyuan Gong #,Danrui Cui #,Dian Liu #,Xiao Shen,Hui Pan,Xiufang Xiong,Yongchao Zhao

Nitric oxide-dependent attenuation of noradrenaline-induced vasoconstriction is impaired in the canine model of Duchenne muscular dystrophy

在杜氏肌营养不良犬模型中,一氧化氮依赖性去甲肾上腺素诱导的血管收缩减弱作用受损。

Kodippili, Kasun; Hakim, Chady H; Yang, Hsiao T; Pan, Xiufang; Yang, N Nora; Laughlin, Maurice H; Terjung, Ronald L; Duan, Dongsheng

Dual AAV Gene Therapy for Duchenne Muscular Dystrophy with a 7-kb Mini-Dystrophin Gene in the Canine Model

在犬模型中,利用7 kb微型肌营养不良蛋白基因进行双重AAV基因疗法治疗杜氏肌营养不良症

Kodippili, Kasun; Hakim, Chady H; Pan, Xiufang; Yang, Hsiao T; Yue, Yongping; Zhang, Yadong; Shin, Jin-Hong; Yang, N Nora; Duan, Dongsheng