Pang Da相关文献与解析，生知库 | 链接生命科学的每一步

Camrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-Negative Breast Cancer: The CamRelief Randomized Clinical Trial

卡瑞利珠单抗联合化疗作为早期或局部晚期三阴性乳腺癌患者新辅助治疗的疗效比较：CamRelief随机临床试验

期刊:Journal of the American Medical Association

doi:10.1001/jama.2024.23560

Chen, Li; Li, Hui; Zhang, Hao; Yang, Huawei; Qian, Jun; Li, Zhihua; Ren, Yu; Wang, Shu; Fu, Peifen; Yang, Hongjian; Liu, Yunjiang; Sun, Jing; Nie, Jianyun; Lei, Ruiwen; Yao, Yongzhong; Zhang, Anqin; Wang, Shouman; Ma, Xiaopeng; Ouyang, Zhong; Yang, Hongwei; Wu, Song-Yang; Cao, Shuo-Wen; Wang, Kun; Jiang, Aimei; Ouyang, Quchang; Pang, Da; Wei, Limin; Zha, Xiaoming; Shen, Yu; Qu, Xiangwen; Wu, Fei; Zhu, Xiaoyu; Wang, Zhonghua; Fan, Lei; Shao, Zhi-Ming

Engineered crRNA Drives RPA-T7-CRISPR/Cas14a Cascade for Ultrasensitive Detection of ctDNA PIK3CA H1047R

工程化crRNA驱动RPA-T7-CRISPR/Cas14a级联反应，实现ctDNA PIK3CA H1047R的超灵敏检测

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202507126

Yu, Yuanyuan; Jin, Mengru; Yuan, Weiguang; Gong, Yajie; Li, Siwei; Qin, Xuquan; Hou, Jianxun; Liu, Jialin; Liu, Siyu; Li, Hui; Chu, Yijun; Wang, Yingjie; Zhang, Youxue; Fang, Fang; Hao, Wenhui; Gu, Yuling; Fan, Qinchen; Lin, Jing; Pang, Da; Zhang, Xianyu

信号转导

发表日期：2025

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FTO activates PD-L1 promotes immunosuppression in breast cancer via the m6A/YTHDF3/PDK1 axis under hypoxic conditions

在缺氧条件下，FTO通过m6A/YTHDF3/PDK1轴激活PD-L1，促进乳腺癌的免疫抑制。

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2024.12.026

Wang, Siyu; Zhang, Xingda; Chen, Quanrun; Wu, Hao; Cao, Shihan; Zhao, Shilu; Li, Guozheng; Wang, Jianyu; Gong, Yajie; Wang, Xinheng; Pang, Da; Gao, Song

H4K79 and H4K91 histone lactylation, newly identified lactylation sites enriched in breast cancer.

H4K79 和 H4K91 组蛋白乳酸化，是新发现的在乳腺癌中富集的乳酸化位点

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:12.8

doi:10.1186/s13046-025-03512-6

Liu Jiena, Zhao Liuying, Yan Meisi, Jin Shengye, Shang Lingmin, Wang Jianyu, Wang Qin, Zhao Shilu, Shen Zibo, Liu Tong, Wu Hao, Pang Da

Discovery and validation of cell-free DNA methylation markers for specific diagnosis, differentiation from benign tumors, and prognosis of breast cancer

发现并验证用于乳腺癌特异性诊断、与良性肿瘤鉴别及预后的无细胞DNA甲基化标记物

期刊:Breast Cancer Research

影响因子:5.6

doi:10.1186/s13058-025-02066-x

Gao, Lijing; Zhang, Lei; Liu, Jinyin; Wang, Liwan; Fu, Qingzhen; Liu, Siyu; Li, Yanbing; Qu, Chao; Zhao, Ning; Tan, Shiheng; Fang, Fang; Tian, Tian; Jiang, Shi; Wu, Junxiao; Dong, Yan; Gong, Yajie; Cao, Yukun; Wang, Fan; Zhang, Xianyu; Pang, Da; Zhao, Yashuang

Author Correction: Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

作者更正：携带 CD163 点突变的转基因猪对 HP-PRRSV 感染具有抵抗力

期刊:Zoological Research

影响因子:4.7

doi:10.24272/j.issn.2095-8137.2025.304

Liu, Ying; Yang, Lin; Xiang, Hong-Yong; Niu, Ming; Deng, Jia-Cheng; Li, Xue-Yuan; Hao, Wen-Jie; Ou-Yang, Hong-Sheng; Liu, Tong-Yu; Tang, Xiao-Chun; Pang, Da-Xin; Yuan, Hong-Ming

Mechanistic study of N-acetyltransferase 10 deficiency enhancing olaparib sensitivity in triple negative breast cancer by inhibiting RAD51 N4-acetylcytidine modification.

N-乙酰转移酶10缺乏通过抑制RAD51 N4-乙酰胞苷修饰增强三阴性乳腺癌对奥拉帕尼的敏感性的机制研究

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.112860

Li Hui, Wu Hao, Li Siwei, Wang Qin, Li Guozheng, Ma Xin, Gong Yajie, Chu Yijun, Jin Shengye, Chen Xi, Zhang Xianyu, Pang Da

Genome-wide discovery of circulating cell-free DNA methylation signatures for the differential diagnosis of triple-negative breast cancer

利用全基因组方法发现循环游离DNA甲基化特征，用于三阴性乳腺癌的鉴别诊断

期刊:PeerJ

影响因子:2.4

doi:10.7717/peerj.19888

Gao, Lijing; Li, Yanbing; Qu, Chao; Dong, Yan; Fu, Qingzhen; Zhou, Haibo; Zhao, Ning; Zhang, Xianyu; Pang, Da; Zhao, Yashuang

Neoadjuvant-adjuvant pertuzumab in HER2-positive early breast cancer: final analysis of the randomized phase III PEONY trial

帕妥珠单抗新辅助-辅助治疗HER2阳性早期乳腺癌：随机III期PEONY试验的最终分析

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-45591-7

Huang, Liang; Pang, Da; Yang, Hongjian; Li, Wei; Wang, Shusen; Cui, Shude; Liao, Ning; Wang, Yongsheng; Wang, Chuan; Chang, Yuan-Ching; Wang, Hwei-Chung; Kang, Seok Yun; Seo, Jae Hong; Shen, Kunwei; Laohawiriyakamol, Suphawat; Jiang, Zefei; Wang, Haiyan; Lamour, François; Song, Grace; Curran, Michelle; Duan, Chunzhe; Lysbet de Haas, Sanne; Restuccia, Eleonora; Shao, Zhimin

Oncolytic viruses for triple negative breast cancer and beyond

用于治疗三阴性乳腺癌及其他疾病的溶瘤病毒

Camrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-Negative Breast Cancer: The CamRelief Randomized Clinical Trial

卡瑞利珠单抗联合化疗作为早期或局部晚期三阴性乳腺癌患者新辅助治疗的疗效比较：CamRelief随机临床试验

Engineered crRNA Drives RPA-T7-CRISPR/Cas14a Cascade for Ultrasensitive Detection of ctDNA PIK3CA H1047R

工程化crRNA驱动RPA-T7-CRISPR/Cas14a级联反应，实现ctDNA PIK3CA H1047R的超灵敏检测

FTO activates PD-L1 promotes immunosuppression in breast cancer via the m6A/YTHDF3/PDK1 axis under hypoxic conditions

在缺氧条件下，FTO通过m6A/YTHDF3/PDK1轴激活PD-L1，促进乳腺癌的免疫抑制。

H4K79 and H4K91 histone lactylation, newly identified lactylation sites enriched in breast cancer.

H4K79 和 H4K91 组蛋白乳酸化，是新发现的在乳腺癌中富集的乳酸化位点

Discovery and validation of cell-free DNA methylation markers for specific diagnosis, differentiation from benign tumors, and prognosis of breast cancer

发现并验证用于乳腺癌特异性诊断、与良性肿瘤鉴别及预后的无细胞DNA甲基化标记物

Author Correction: Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

作者更正：携带 CD163 点突变的转基因猪对 HP-PRRSV 感染具有抵抗力

Mechanistic study of N-acetyltransferase 10 deficiency enhancing olaparib sensitivity in triple negative breast cancer by inhibiting RAD51 N4-acetylcytidine modification.

N-乙酰转移酶10缺乏通过抑制RAD51 N4-乙酰胞苷修饰增强三阴性乳腺癌对奥拉帕尼的敏感性的机制研究

Genome-wide discovery of circulating cell-free DNA methylation signatures for the differential diagnosis of triple-negative breast cancer

利用全基因组方法发现循环游离DNA甲基化特征，用于三阴性乳腺癌的鉴别诊断

Neoadjuvant-adjuvant pertuzumab in HER2-positive early breast cancer: final analysis of the randomized phase III PEONY trial

帕妥珠单抗新辅助-辅助治疗HER2阳性早期乳腺癌：随机III期PEONY试验的最终分析