日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of a Potent, Selective, and In Vivo Efficacious Covalent Inhibitor for Lysine Methyltransferase SETD8

发现一种高效、选择性强且体内有效的赖氨酸甲基转移酶SETD8共价抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02958
Chen, He; Dutta, Rudra Prasad; Li, Zhizhong; Zhong, Yue; Ma, Anqi; Park, Kwang-Su; Kottur, Jithesh; Park, Alison; Babault, Nicolas; Wang, Ke; Wang, Dandan; Xiong, Yan; Kaniskan, H Ümit; Luo, Minkui; Parekh, Samir; Jin, Jian
SET
发表日期：2026
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Development of a brain-penetrant G9a methylase inhibitor to target Alzheimer's disease-associated proteopathology.

开发一种可穿透血脑屏障的 G9a 甲基化酶抑制剂，以靶向治疗阿尔茨海默病相关的蛋白质病理

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-59128-z
Xie Ling, Sheehy Ryan N, Muneer Adil, Xiong Yan, Wrobel John A, Zhang Feng, Park Kwang-Su, Velez Julia, Liu Jing, Luo Yan-Jia, Asrican Brent, Dong Ping, Li Ya-Dong, Damian Corina, Quintanilla Luis, Li Yongyi, Xu Chongchong, Deshmukh Mohanish, Coleman Leon G Jr, Ming Guo-Li, Song Hongjun, Wen Zhexing, Jin Jian, Song Juan, Chen Xian
表观遗传
DNA甲基化
发表日期：2025
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PROTAC Delivery Strategies for Overcoming Physicochemical Properties and Physiological Barriers in Targeted Protein Degradation

PROTAC递送策略克服靶向蛋白质降解中的理化性质和生理障碍

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17040501
Syahputra, Endry Wahyu; Lee, Hyunji; Cho, Hyukjun; Park, Hyun Jin; Park, Kwang-Su; Hwang, Duhyeong
发表日期：2025
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Advancing PROTAC Discovery Through Artificial Intelligence: Opportunities, Challenges, and Future Directions

利用人工智能推进PROTAC发现：机遇、挑战与未来方向

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph18121793
Park, Kwang-Su; Jeon, Minji
发表日期：2025
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Epigenomic analysis identifies DTP subpopulation using HOPX to develop targeted therapy resistance in lung adenocarcinoma.

利用 HOPX 进行表观基因组分析，识别 DTP 亚群，从而在肺腺癌中产生靶向治疗耐药性

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.112387
Tian Yang, Bhattacharya Reshmee, Yoo Seungyeul, Jiang Feng, Park Eric, Lara Granados Genesis, Shen Yudao, Park Kwang-Su, Kaniskan Husnu Umit, Jin Jian, Hopkins Benjamin D, Zhu Jun, Watanabe Hideo
肿瘤
肺癌
HOP
肿瘤免疫
发表日期：2025
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Molecular Therapy’s growing influence

分子疗法的影响力日益增强

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2024.05.034
Wang, Sung Eun; Xiong, Yan; Jang, Mi-Ae; Park, Kwang-Su; Donahue, Meaghan; Velez, Julia; Jin, Jian; Jiang, Yong-Hui; Herzog, Roland W; Bricker-Anthony, Rory
发表日期：2024
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Assessment of the mandibular incisive and mental canal in dentate and edentulous mandibles using cone-beam computed tomography

利用锥形束计算机断层扫描评估有牙颌和无牙颌下颌骨的下颌切牙管和颏管

期刊:Heliyon
影响因子:3.6
doi:10.1016/j.heliyon.2024.e39487
Doh, Re-Mee; Choi, Dong-Jin; Park, Kwang-Su; Jung, Bock-Young
发表日期：2024
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Advancing targeted protein degradation for cancer therapy

推进靶向蛋白质降解在癌症治疗中的应用

期刊:Nature Reviews Cancer
影响因子:66.8
doi:10.1038/s41568-021-00365-x
Dale, Brandon; Cheng, Meng; Park, Kwang-Su; Kaniskan, H Ümit; Xiong, Yue; Jin, Jian
肿瘤
肿瘤免疫
发表日期：2021
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A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models

一种选择性WDR5降解剂可抑制患者来源小鼠模型中的急性髓系白血病。

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.abj1578
Yu, Xufen; Li, Dongxu; Kottur, Jithesh; Shen, Yudao; Kim, Huen Suk; Park, Kwang-Su; Tsai, Yi-Hsuan; Gong, Weida; Wang, Jun; Suzuki, Kyogo; Parker, Joel; Herring, Laura; Kaniskan, H Ümit; Cai, Ling; Jain, Rinku; Liu, Jing; Aggarwal, Aneel K; Wang, Gang Greg; Jin, Jian
白血病
WDR5
发表日期：2021
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Structure-Based Design, Docking and Binding Free Energy Calculations of A366 Derivatives as Spindlin1 Inhibitors

基于结构的A366衍生物作为Spindlin1抑制剂的设计、对接和结合自由能计算

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms22115910
Luise, Chiara; Robaa, Dina; Regenass, Pierre; Maurer, David; Ostrovskyi, Dmytro; Seifert, Ludwig; Bacher, Johannes; Burgahn, Teresa; Wagner, Tobias; Seitz, Johannes; Greschik, Holger; Park, Kwang-Su; Xiong, Yan; Jin, Jian; Schüle, Roland; Breit, Bernhard; Jung, Manfred; Sippl, Wolfgang
发表日期：2021
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