日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Frizzled5 controls murine intestinal epithelial cell plasticity through organization of chromatin accessibility

Frizzled5通过调控染色质可及性来控制小鼠肠道上皮细胞的可塑性。

期刊:Developmental Cell
影响因子:10.7
doi:10.1016/j.devcel.2024.10.021
Lu Deng ,Xi C He ,Shiyuan Chen ,Ning Zhang ,Fengyan Deng ,Allison Scott ,Yanfeng He ,Dai Tsuchiya ,Sarah E Smith ,Michael Epp ,Seth Malloy ,Fang Liu ,Mark Hembree ,Qinghui Mu ,Jeffrey S Haug ,Ermanno Malagola ,Huzaifa Hassan ,Kaitlyn Petentler ,Rhonda Egidy ,Lucinda Maddera ,Jonathon Russell ,Yan Wang ,Hua Li ,Chongbei Zhao ,Anoja Perera ,Timothy C Wang ,Calvin J Kuo ,Linheng Li
上皮细胞
信号转导
细胞生物学
发表日期：2025
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A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer

双重MET激酶/OCT-2抑制剂OMO-1治疗转移性实体恶性肿瘤（包括MET外显子14突变肺癌）的I期临床试验

期刊:Oncologist
影响因子:4.2
doi:10.1093/oncolo/oyad146
Pruis, Melinda A; Krebs, Matthew G; Plummer, Ruth; De Vos, Filip; Angevin, Eric; Prenen, Hans; Forster, Martin D; Clack, Glen; Van der Aa, Annegret; Tjwa, Marc; Jansen, Ellen; Perera, Timothy; Lolkema, Martijn P
肺癌
肿瘤
肿瘤免疫
信号转导
MET
发表日期：2023
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One cisplatin dose provides durable stimulation of anti-tumor immunity and alleviates anti-PD-1 resistance in an intraductal model for triple-negative breast cancer.

在三阴性乳腺癌的导管内模型中，单剂量顺铂可持久刺激抗肿瘤免疫力并减轻抗 PD-1 耐药性

期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2022.2103277
Steenbrugge Jonas, Bellemans Julie, Vander Elst Niels, Demeyere Kristel, De Vliegher Josephine, Perera Timothy, De Wever Olivier, Van Den Broeck Wim, De Spiegelaere Ward, Sanders Niek N, Meyer Evelyne
肿瘤
乳腺癌
肿瘤免疫
发表日期：2022
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OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer.

在基于 4T1 的非 c-MET 依赖性导管内三阴性乳腺癌小鼠模型中，OMO-1 可降低疾病进展并增强顺铂疗效

期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-021-00234-8
Steenbrugge Jonas, Vander Elst Niels, Demeyere Kristel, De Wever Olivier, Sanders Niek N, Van Den Broeck Wim, Ciamporcero Eric, Perera Timothy, Meyer Evelyne
肿瘤
乳腺癌
Mouse
发表日期：2021
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MET inhibition overcomes radiation resistance of glioblastoma stem-like cells

MET抑制剂可克服胶质母细胞瘤干细胞样细胞的放射抗性

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.15252/emmm.201505890
De Bacco, Francesca; D'Ambrosio, Antonio; Casanova, Elena; Orzan, Francesca; Neggia, Roberta; Albano, Raffaella; Verginelli, Federica; Cominelli, Manuela; Poliani, Pietro L; Luraghi, Paolo; Reato, Gigliola; Pellegatta, Serena; Finocchiaro, Gaetano; Perera, Timothy; Garibaldi, Elisabetta; Gabriele, Pietro; Comoglio, Paolo M; Boccaccio, Carla
细胞生物学
发育与干细胞
MET
干细胞
发表日期：2016
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C-met inhibition blocks bone metastasis development induced by renal cancer stem cells

C-met抑制剂可阻断肾癌干细胞诱导的骨转移发展

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.9997
D'Amico, Lucia; Belisario, Dimas; Migliardi, Giorgia; Grange, Cristina; Bussolati, Benedetta; D'Amelio, Patrizia; Perera, Timothy; Dalmasso, Ettore; Dalle Carbonare, Luca; Godio, Laura; Comoglio, Paolo; Trusolino, Livio; Ferracini, Riccardo; Roato, Ilaria
肿瘤
肿瘤免疫
细胞生物学
肾癌
干细胞
发育与干细胞
发表日期：2016
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Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

MET受体扩增导致结直肠癌对EGFR抑制剂产生耐药性

期刊:Cancer Discovery
影响因子:33.3
doi:10.1158/2159-8290.CD-12-0558
Bardelli, Alberto; Corso, Simona; Bertotti, Andrea; Hobor, Sebastijan; Valtorta, Emanuele; Siravegna, Giulia; Sartore-Bianchi, Andrea; Scala, Elisa; Cassingena, Andrea; Zecchin, Davide; Apicella, Maria; Migliardi, Giorgia; Galimi, Francesco; Lauricella, Calogero; Zanon, Carlo; Perera, Timothy; Veronese, Silvio; Corti, Giorgio; Amatu, Alessio; Gambacorta, Marcello; Diaz, Luis A Jr; Sausen, Mark; Velculescu, Victor E; Comoglio, Paolo; Trusolino, Livio; Di Nicolantonio, Federica; Giordano, Silvia; Siena, Salvatore
肿瘤
肠癌
肿瘤免疫
信号转导
EGF
EGFR
MET
发表日期：2013
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