日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Atypical tetracyclines promote longevity and ferroptotic neuroprotection via translation attenuation

非典型四环素类药物通过抑制翻译来延长寿命并发挥铁死亡神经保护作用。

Clay, Khalyd J; Sanchez-Alavez, Manuel; Newman, Ian; Na, Na; Verduzco Espinoza, Ana P; To, Alan; Saad, Shannon; Cline, Hollis T; Petrascheck, Michael

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan

自噬激活剂AA-20改善蛋白质稳态并延长秀丽隐杆线虫的寿命

Tan, Ee Phie; Lyang, Nora; Doroodian, Saam; Sanz-Martinez, Pablo; Xu, Jin; Zaretski, Sviatlana; Nieto-Torres, José L; Ebata, Hiroshi; Lim, Shaun H Y; Hou, William C; Clay, Khalyd J; Yoon, Leonard; Massey, Lynée A; Rhoades, Derek; Garza, Danny; Johnson, Kristen A; To, Alan; Ambaye, Lydia; Bentley, Emily P; Petrascheck, Michael; Stolz, Alexandra; Kelly, Jeffery W; Hansen, Malene

Activity-dependent synthesis of Emerin gates neuronal plasticity by regulating proteostasis

Emerin 的活动依赖性合成通过调节蛋白质稳态来控制神经元可塑性

Yi Xie,Ruoxi Wang,Daniel B McClatchy,Yuanhui Ma,Jolene Diedrich,Manuel Sanchez-Alavez,Michael Petrascheck,John R Yates 3rd,Hollis T Cline

AI-Driven Identification of Exceptionally Efficacious Polypharmacological Compounds That Extend the Lifespan of Caenorhabditis elegans

人工智能驱动的、能够延长秀丽隐杆线虫寿命的高效多药理化合物的鉴定

Avchaciov, Konstantin; Clay, Khalyd J; Denisov, Kirill A; Burmistrova, Olga; Petrascheck, Michael; Fedichev, Peter O

TargetSeeker-MS: A Bayesian Inference Approach for Drug-Target Discovery Using Protein Fractionation Coupled to Mass Spectrometry

TargetSeeker-MS:一种利用蛋白质分级分离与质谱联用进行药物靶点发现的贝叶斯推断方法

Lavallée-Adam, Mathieu; Pelletier, Alexander; Diedrich, Jolene K; Pinto, Antonio F M; Martínez-Bartolomé, Salvador; Petrascheck, Michael; Moresco, James J; Yates, John R 3rd

Nucleosome stability safeguards cell identity, stress resilience and healthy aging

核小体稳定性保障细胞特性、抗压能力和健康衰老。

Tanaka, Hiroshi; McCauley, Brenna S; Guida, Clara; Lei, Xue; Li, Sha; Moreno, Tatiana M; Guillotte, K'leigh; Chua, Zong-Ming; Abele, Adrianna; Lamba, Aashna; Arnold, Rouven; Rajesh, Adarsh; Teneche, Marcos G; Haddadin, Laurence; Deshpande, Anagha; Deshpande, Aniruddha J; Colas, Alexandre; Kumsta, Caroline; Petrascheck, Michael; Bodmer, Rolf; Dang, Weiwei; Adams, Peter D

Uncoupling overeating and fat storage by modulation of different serotonergic receptors

通过调节不同的血清素受体来解除过度进食和脂肪储存的关联

Clark, Christina; Zapata, Rizaldy C; Newman, Ian R; Osborn, Olivia; Petrascheck, Michael

Quantifying Food Intake in Caenorhabditis elegans by Measuring Bacterial Clearance.

通过测量细菌清除率来量化秀丽隐杆线虫的食物摄入量

Clark Christina, To Alan, Petrascheck Michael

Multiple Targets, One Goal: Compounding life-extending effects through Polypharmacology

多靶点,同一目标:通过多药理学增强延长寿命的效果

Avchaciov, K; Clay, K J; Denisov, K; Burmistrova, O; Petrascheck, M; Fedichev, P

Targeting Clic1 for the treatment of obesity: A novel therapeutic strategy to reduce food intake and body weight

针对 Clic1 治疗肥胖症:减少食物摄入和体重的新型治疗策略

Rizaldy C Zapata, Dinghong Zhang, Dongmin Yoon, Chanond A Nasamran, Daisy R Chilin-Fuentes, Avraham Libster, Besma S Chaudry, Mariela Lopez-Valencia, Devasena Ponnalagu, Harpreet Singh, Michael Petrascheck, Olivia Osborn