日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineered Bi-Specific AChR CAAR T Cells for Selective Elimination of Myasthenia Gravis B Cells

工程化双特异性AChR CAAR T细胞用于选择性消除重症肌无力B细胞

von Wardenburg, Niels; Spagni, Gregorio; Reincke, S Momsen; Wernick, Stephanie; Kornau, Hans-Christian; Zinnow, Viktoria; Keles, Amelya; Li, Lucie Y; Homeyer, Marie A; Blumenau, Sonja; Stecklum, Maria; Schmitz, Dietmar; Pelz, Andreas; Damato, Valentina; Sanderson, Nicholas; Derfuß, Tobias; Pham, Minh C; O'Connor, Kevin C; Meisel, Andreas; Prüss, Harald

Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures.

通过肌肉乙酰胆碱受体结构阐明自身免疫机制

Li Huanhuan, Pham Minh C, Teng Jinfeng, O'Connor Kevin C, Noviello Colleen M, Hibbs Ryan E

IgA autoantibodies demonstrate a novel mechanism of MuSK myasthenia gravis pathology

IgA自身抗体揭示了MuSK重症肌无力病理学的一种新机制

Masi, Gianvito; Chen, Kangzhi; Bayer, Alexandra C; Bayarri-Olmos, Rafael; Pham, Minh C; Wallace, Annabel; Falso, Silvia; Evoli, Amelia; Iorio, Raffaele; Hoehn, Kenneth B; Iwasaki, Akiko; Nowak, Richard J; O'Connor, Kevin C

Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology

治疗性IgG和IgM特异性蛋白酶可消除驱动重症肌无力病理的乙酰胆碱受体自身抗体。

Bayer, Alexandra C; Sanmarco, Liliana M; Pellerin, Alex; Masi, Gianvito; Plasencia, Agustin; Anderson, Jordan M; Nowak, Richard J; Damato, Valentina; Massacesi, Luca; Pham, Minh C; Khani-Habibabadi, Fatemeh; Vital, Heather; Higginson-Scott, Nathan; Otipoby, Kevin L; Xing, Yi; Mascanfroni, Ivan D; O'Connor, Kevin C

AChR Autoantibody Pathogenic Properties Are Heterogeneously Distributed and Undergo Temporal Changes Among Patients With Myasthenia Gravis

AChR自身抗体的致病特性在重症肌无力患者中分布不均,并随时间发生变化

Khani-Habibabadi, Fatemeh; Roy, Bhaskar; Pham, Minh C; Obaid, Abeer H; Filipek, Beata; Nowak, Richard J; O'Connor, Kevin C

Fluorescence-detection size-exclusion chromatography specifically detects autoantibodies targeting the ganglionic acetylcholine receptor in patients with autoimmune autonomic ganglionopathy

荧光检测尺寸排阻色谱法可特异性检测自身免疫性自主神经节病患者体内靶向神经节乙酰胆碱受体的自身抗体。

Baxter, Leah; Hopkins, Steven; O'Connor, Kevin C; Pham, Minh C; Nowak, Richard J; Monson, Nancy L; Blackburn, Kyle; Hibbs, Ryan E; Vernino, Steven; Noviello, Colleen M

Clinicoserological insights into patients with immune checkpoint inhibitor-induced myasthenia gravis

免疫检查点抑制剂诱发重症肌无力患者的临床血清学见解

Masi, Gianvito; Pham, Minh C; Karatz, Tabitha; Oh, Sangwook; Payne, Aimee S; Nowak, Richard J; Howard, James F Jr; Guptill, Jeffrey T; Juel, Vern C; O'Connor, Kevin C

The clinical need for clustered AChR cell-based assay testing of seronegative MG

对血清阴性重症肌无力患者进行基于簇状乙酰胆碱受体细胞的检测的临床需求

Masi, Gianvito; Li, Yingkai; Karatz, Tabitha; Pham, Minh C; Oxendine, Seneca R; Nowak, Richard J; Guptill, Jeffrey T; O'Connor, Kevin C

Molecular determinants of permeation in a fluoride-specific ion channel

氟离子特异性通道渗透性的分子决定因素

Last, Nicholas B; Sun, Senmiao; Pham, Minh C; Miller, Christopher