Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose
发现N-三取代嘧啶衍生物作为I型RET和RET门控突变体抑制剂，具有新型激酶结合姿势
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c01280
Lingtian Zhang ,Marialuisa Moccia ,David C Briggs ,Jaideep B Bharate ,Naga Rajiv Lakkaniga ,Phillip Knowles ,Wei Yan ,Phuc Tran ,Anupreet Kharbanda ,Xiuqi Wang ,Yuet-Kin Leung ,Brendan Frett ,Massimo Santoro ,Neil Q McDonald ,Francesca Carlomagno ,Hong-Yu Li
