The glycosyltransferase ST3GAL4 drives immune evasion in acute myeloid leukemia by synthesizing ligands for the glyco-immune checkpoint receptor Siglec-9.
糖基转移酶 ST3GAL4 通过合成糖免疫检查点受体 Siglec-9 的配体,驱动急性髓系白血病的免疫逃逸
期刊:Leukemia
影响因子:13.4
doi:10.1038/s41375-024-02454-w
Krishnamoorthy Vignesh, Daly John, Kim Jimmy, Piatnitca Lidia, Yuen Katie A, Kumar Bhoj, Taherzadeh Ghahfarrokhi Mehrnoush, Bui Tom Q T, Azadi Parastoo, Vu Ly P, Wisnovsky Simon