日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Acyl-CoA Synthetase 5 Knockout and Inhibitors Protect Against Diet-Induced Obesity in Mice by Activating the Ileal Brake

酰基辅酶A合成酶5基因敲除及其抑制剂通过激活回肠制动来保护小鼠免受饮食诱导的肥胖影响

期刊:Journal of the Endocrine Society
影响因子:3.1
doi:10.1210/jendso/bvaf196
Powell, David R; Van Sligtenhorst, Isaac; Main, Alan; Jin, Haihong; Carson, Kenneth G; Shi, Zhi-Cai; Swaffield, Jonathan; Smith, Melinda; Harris, Angela; Gopinathan, Suma; Platt, Kenneth A; Wade, Jeffrey; Zambrowicz, Brian; McDonald, Patricia; Orton, Darren; Kuttippurathu, Lakshmi; Mullens, Michael; Greer, Jennifer; Yang, Qi Melissa; Ding, Zhi-Ming
肥胖
代谢
发表日期：2026
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Mice Lacking Gpr75 are Hypophagic and Thin

缺乏Gpr75的小鼠表现出食欲减退和体型偏瘦。

期刊:Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
影响因子:3
doi:10.2147/DMSO.S342799
Powell, David R; Doree, Deon D; DaCosta, Christopher M; Platt, Kenneth A; Brommage, Robert; Buhring, Lindsey; Revelli, Jean-Pierre; Shadoan, Melanie K
发表日期：2022
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High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes

对小鼠基因敲除进行高通量筛选，鉴定出已知的和新的高体脂表型

期刊:Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
影响因子:3
doi:10.2147/DMSO.S322083
Powell, David R; Revelli, Jean-Pierre; Doree, Deon D; DaCosta, Christopher M; Desai, Urvi; Shadoan, Melanie K; Rodriguez, Lawrence; Mullens, Michael; Yang, Qi M; Ding, Zhi-Ming; Kirkpatrick, Laura L; Vogel, Peter; Zambrowicz, Brian; Sands, Arthur T; Platt, Kenneth A; Hansen, Gwenn M; Brommage, Robert
Mouse
发表日期：2021
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Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity

G2E3基因敲除小鼠的肥胖表明，人类G2E3基因附近的肥胖相关变异会降低G2E3的活性。

期刊:Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
影响因子:3
doi:10.2147/DMSO.S259546
Powell, David R; Doree, Deon D; DaCosta, Christopher M; Platt, Kenneth A; Hansen, Gwenn M; van Sligtenhorst, Isaac; Ding, Zhi-Ming; Revelli, Jean-Pierre; Brommage, Robert
Human
肥胖
代谢
发表日期：2020
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Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus.

敲除钠-葡萄糖转运蛋白 SGLT2 可减轻糖尿病患者的高血糖和肾小球高滤过，但不会造成肾脏生长或损伤

期刊:American Journal of Physiology-Renal Physiology
影响因子:3.4
doi:10.1152/ajprenal.00409.2012
Vallon Volker, Rose Michael, Gerasimova Maria, Satriano Joseph, Platt Kenneth A, Koepsell Hermann, Cunard Robyn, Sharma Kumar, Thomson Scott C, Rieg Timo
代谢
糖尿病
发表日期：2013
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SGLT2 mediates glucose reabsorption in the early proximal tubule

SGLT2介导近端小管早期对葡萄糖的重吸收

期刊:Journal of the American Society of Nephrology
影响因子:9.4
doi:10.1681/ASN.2010030246
Vallon, Volker; Platt, Kenneth A; Cunard, Robyn; Schroth, Jana; Whaley, Jean; Thomson, Scott C; Koepsell, Hermann; Rieg, Timo
SGLT2
发表日期：2011
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Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.

MAPK p38delta 对 PKD 在胰岛素分泌和葡萄糖稳态中的调节作用

期刊:Cell
影响因子:42.5
doi:10.1016/j.cell.2008.11.018
Sumara Grzegorz, Formentini Ivan, Collins Stephan, Sumara Izabela, Windak Renata, Bodenmiller Bernd, Ramracheya Reshma, Caille Dorothée, Jiang Huiping, Platt Kenneth A, Meda Paolo, Aebersold Rudolf, Rorsman Patrik, Ricci Romeo
代谢
发表日期：2009
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