日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reprogramming Listeria monocytogenes flavin metabolism to improve its therapeutic safety profile and broaden innate T-cell activation

通过重编程单核细胞增生李斯特菌的黄素代谢来提高其治疗安全性并扩大先天性T细胞活化范围

Chevée, Victoria; Lobanovska, Mariya; Rivera-Lugo, Rafael; Güereca, Leslie; Feng, Ying; Anaya-Sanchez, Andrea; Garcia Castillo, Jesse; Huckins, Austin M; Lemmens, Edward E; Rae, Chris S; Hardy, Jonathan W; Carrington, Russell; Kotula, Jonathan W; Portnoy, Daniel A

Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy.

细菌抗肿瘤免疫疗法产生有益作用与有害作用的细胞机制。

Garcia Castillo Jesse, Fernandez Sebastian, Campbell Timothy, Gonzalez Ventura Diego, Williams Jacob, Ybarra Julia, Flores Hernandez Nicole, Wells Elina, Portnoy Daniel A, DuPage Michel

Methylglyoxal is an antibacterial effector produced by macrophages during infection.

甲基乙二醛是巨噬细胞在感染过程中产生的一种抗菌效应物质

Anaya-Sanchez Andrea, Berry Samuel B, Espich Scott, Zilinskas Alex, Tran Phuong M, Agudelo Carolina, Samani Helia, Darwin K Heran, Portnoy Daniel A, Stanley Sarah A

Stress-dependent activation of the Listeria monocytogenes virulence program ensures bacterial resilience during infection

单核细胞增生李斯特菌毒力程序的应激依赖性激活确保了细菌在感染期间的抵抗力。

Lobanovska, Mariya; Feng, Ying; Zhang, Jonathan; Williams, Allison H; Portnoy, Daniel A

The mevalonate pathway of isoprenoid biosynthesis supports metabolic flexibility in Mycobacterium marinum

海分枝杆菌中异戊二烯生物合成的甲羟戊酸途径支持代谢灵活性

Qabar, Christine M; Baidoo, Edward E K; Akyuz Turumtay, Emine; Qayum, Tariq M; Keasling, Jay D; Madigan, Cressida A; Portnoy, Daniel A; Cox, Jeffery S

MAIT cells induced by engineered Listeria exhibit antibacterial and antitumor activity

由基因工程改造的李斯特菌诱导的MAIT细胞表现出抗菌和抗肿瘤活性

Rivera-Lugo, Rafael; Castillo, Jesse Garcia; Lobanovska, Mariya; Tang, Eugene; Anaya-Sanchez, Andrea; Espich, Scott; Stanley, Sarah A; DuPage, Michel; Portnoy, Daniel A

Phosphorylation State Dictates Bacterial Stressosome Assembly and Function

磷酸化状态决定细菌应激体的组装和功能

Martinez-Bond, Elizabeth A; Lopez-Ayala, Ivanna; Lobanovska, Mariya; Qiu, Lisa; Garda, Virginia; Yu, Zanlin; Portnoy, Daniel A; Williams, Allison H

TLR2 signaling uniquely destabilizes tumor Tregs to promote cancer immunotherapy

TLR2信号通路能够独特地破坏肿瘤Treg细胞的稳定性,从而促进癌症免疫治疗。

Campbell, Timothy F; Castillo, Jesse Garcia; Fernandez, Sebastian; Ventura, Diego Gonzalez; Vickery, Jenna; Homentcovschi, Stefan; Hernandez, Nicole Flores; Ybarra, Julia; Portnoy, Daniel A; DuPage, Michel

The mevalonate pathway of isoprenoid biosynthesis supports metabolic flexibility in Mycobacterium marinum.

异戊二烯生物合成的甲羟戊酸途径支持海洋分枝杆菌的代谢灵活性

Qabar Christine M, Baidoo Edward E K, Akyuz Turumtay Emine, Qayum Tariq M, Keasling Jay D, Madigan Cressida A, Portnoy Daniel A, Cox Jeffery S

Temporal and spatial dynamics of Listeria monocytogenes central nervous system infection in mice

单核细胞增生李斯特菌感染小鼠中枢神经系统的时空动态

Chevée, Victoria; Hullahalli, Karthik; Dailey, Katherine G; Güereca, Leslie; Zhang, Chenyu; Waldor, Matthew K; Portnoy, Daniel A