日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nano Plasma Membrane Vesicle-Lipid Nanoparticle Hybrids for Enhanced Gene Delivery and Expression.

用于增强基因递送和表达的纳米质膜囊泡-脂质纳米颗粒杂合物

Alter Claudio Luca, Lotter Claudia, Puligilla Ramya Deepthi, Bolten Jan Stephan, Sedzicki Jaroslaw, Marchese Jason, Schittny Valentin, Rucci Francesca, Beverly Michael, Palivan Cornelia G, Detampel Pascal, Einfalt Tomaž, Huwyler Jörg

Loss of DNA glycosylases improves health and cognitive function in a C. elegans model of human tauopathy

在秀丽隐杆线虫的人类tau蛋白病模型中,DNA糖基化酶的缺失可改善健康和认知功能。

Tiwari, Vinod; Buvarp, Elisabeth; Borbolis, Fivos; Puligilla, Chandrakala; Croteau, Deborah L; Palikaras, Konstantinos; Bohr, Vilhelm A

Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments

评估乙二醇醚等有机溶剂神经毒性的新策略:将体外和计算机模拟方法与人体控制暴露实验相结合的方案

Hopf, Nancy B; Suter-Dick, Laura; Huwyler, Jörg; Borgatta, Myriam; Hegg, Lucie; Pamies, David; Paschoud, Hélène; Puligilla, Ramya Deepthi; Reale, Elena; Werner, Sophie; Zurich, Marie-Gabrielle

The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loops

RNA 结合基序蛋白 14 调节 TERRA 与端粒 R 环界面处的端粒完整性

Yajun Wang, Wei Zhu, Yumi Jang, Joshua A Sommers, Gong Yi, Chandrakala Puligilla, Deborah L Croteau, Yibin Yang, Mihoko Kai, Yie Liu

Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice

长期补充 NAD+ 可防止小鼠因年龄相关而出现的听力损失

Mustafa N Okur, Burcin Duan Sahbaz, Risako Kimura, Uri Manor, Jaimin Patel, Jae-Hyeon Park, Leo Andrade, Chandrakala Puligilla, Deborah L Croteau, Vilhelm A Bohr

Boosting NAD ameliorates hematopoietic impairment linked to short telomeres in vivo

体内实验表明,提高 NAD 水平可改善与端粒短相关的造血功能障碍。

Amanda J Stock ,Saipriya Ayyar ,Amogh Kashyap ,Yunong Wang ,Hagai Yanai ,Matthew F Starost ,Mayuri Tanaka-Yano ,Monica Bodogai ,Chongkui Sun ,Yajun Wang ,Yi Gong ,Chandrakala Puligilla ,Evandro F Fang ,Vilhelm A Bohr ,Yie Liu # ,Isabel Beerman #

High efficiency preparation of monodisperse plasma membrane derived extracellular vesicles for therapeutic applications

高效制备单分散质膜衍生的细胞外囊泡以供治疗应用

Claudio L Alter, Pascal Detampel, Roman B Schefer, Claudia Lotter, Patrick Hauswirth, Ramya D Puligilla, Vera J Weibel, Susanne H Schenk, Wolf Heusermann, Melanie Schürz, Nicole Meisner-Kober, Cornelia Palivan, Tomaž Einfalt #, Jörg Huwyler #

Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney

斑马鱼(Danio rerio)幼鱼作为预测模型研究庆大霉素诱导的肾脏结构改变

Bolten, Jan Stephan; Tanner, Christine; Rodgers, Griffin; Schulz, Georg; Levano, Soledad; Weitkamp, Timm; Waldner, Samuel; Puligilla, Ramya Deepthi; Bodmer, Daniel; Müller, Bert; Huwyler, Jörg

Aberrant expression and localization of the RAP1 shelterin protein contribute to age-related phenotypes

RAP1 保护蛋白的异常表达和定位导致与年龄相关的表型

Amanda J Stock, Ross A McDevitt, Chandrakala Puligilla, Yajun Wang, Yongqing Zhang, Kun Wang, Chongkui Sun, Kevin G Becker, Elin Lehrmann, William H Wood 3rd, Yi Gong, Mohammad Aqdas, Myong-Hee Sung, Victoria Hoffmann, Chengyu Liu, Myriam Gorospe, Lea Harrington, Luigi Ferrucci, Yie Liu

Dual role for Sox2 in specification of sensory competence and regulation of Atoh1 function

Sox2 在感觉能力的指定和 Atoh1 功能的调节中起双重作用

Chandrakala Puligilla, Matthew W Kelley