KLF6-mediated recruitment of the p300 complex enhances H3K23su and cooperatively upregulates SEMA3C with FOSL2 to drive 5-FU resistance in colon cancer cells.
KLF6 介导的 p300 复合物募集增强 H3K23su,并与 FOSL2 协同上调 SEMA3C,从而驱动结肠癌细胞产生 5-FU 耐药性
期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-025-01424-1
Zhang Bishu, Qi Tuoya, Lin Jiewei, Zhai Shuyu, Wang Xuelong, Zhou Leqi, Deng Xiaxing