Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate
谷胱甘肽过氧化物酶3通过AMPK/ERK1/2通路诱导线粒体介导的细胞凋亡,并通过AMPK/mTOR通路抵抗自噬相关的铁死亡,从而在增生性前列腺中发挥作用
期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-023-04432-9
Li, Yan; Zhou, Yongying; Liu, Daoquan; Wang, Zhen; Qiu, Jizhang; Zhang, Junchao; Chen, Ping; Zeng, Guang; Guo, Yuming; Wang, Xinghuan; DiSanto, Michael E; Zhang, Xinhua
凋亡
mTOR
表观遗传
信号转导
AMPK
铁死亡
MAPK/ERK
线粒体
细胞生物学
自噬