Quen J相关文献与解析，生知库 | 链接生命科学的每一步

IFNÎ³-induced memory in human macrophages is not sustained by epigenetic changes but the durability of the cytokine itself.

IFNγ诱导的人类巨噬细胞记忆不是通过表观遗传变化来维持的，而是通过细胞因子本身的持久性来维持的

期刊:

影响因子:

doi:10.1101/2025.06.12.659073

Gorin Aleksandr, Harriott Noa, Koduvayur Vyas, Cheng Quen J, Hoffmann Alexander

GM-CSF receptor expression determines opposing innate memory phenotypes at different stages of myelopoiesis

GM-CSF受体表达决定了髓系造血不同阶段的相反的先天记忆表型

期刊:Blood

影响因子:23.1

doi:10.1182/blood.2024024330

Guerrero, Paula; Bono, Cristina; Sobén, María; Guiu, Andrea; Cheng, Quen J; Gil, M Luisa; Yáñez, Alberto

Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks

Dectin-1 配体通过信号网络的差异激活在人类单核细胞中产生不同的训练表型

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-024-51620-8

Quen J Cheng, Kylie Farrell, Jeffrey Fenn, Zuchao Ma, Sara K Makanani, Jonathan Siemsen

The Use of Next-Generation Sequencing to Assist in the Diagnosis of Atypical Vasculitis

利用新一代测序技术辅助诊断非典型血管炎

期刊:Cureus Journal of Medical Science

影响因子:1.3

doi:10.7759/cureus.73247

Chetrit, David A; Aung, Thanda; Cheng, Quen J; King, Jennifer

Sequencing

发表日期：2024

文献求助收藏

A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes

刺激相关的正反馈回路使 IFN-β 剂量依赖性地激活促炎基因

期刊:Molecular Systems Biology

影响因子:8.5

doi:10.15252/msb.202211294

Catera L Wilder, Diane Lefaudeux, Raisa Mathenge, Kensei Kishimoto, Alma Zuniga Munoz, Minh A Nguyen, Aaron S Meyer, Quen J Cheng, Alexander Hoffmann

信号转导

发表日期：2023

文献求助收藏

Stochastic models of nucleosome dynamics reveal regulatory rules of stimulus-induced epigenome remodeling

核小体动力学随机模型揭示刺激诱导的表观基因组重塑的调控规则

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2022.111076

Jinsu Kim, Katherine M Sheu, Quen J Cheng, Alexander Hoffmann, German Enciso

信号转导

发表日期：2022

文献求助收藏

NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages

NF-κB动态变化决定巨噬细胞表观基因组重编程的刺激特异性

期刊:Science

影响因子:45.8

doi:10.1126/science.abc0269

Cheng, Quen J; Ohta, Sho; Sheu, Katherine M; Spreafico, Roberto; Adelaja, Adewunmi; Taylor, Brooks; Hoffmann, Alexander

High Dose IFN- β Activates GAF to Enhance Expression of ISGF3 Target Genes in MLE12 Epithelial Cells

高剂量 IFN-β 激活 GAF 增强 MLE12 上皮细胞中 ISGF3 靶基因的表达

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2021.651254

Kensei Kishimoto, Catera L Wilder, Justin Buchanan, Minh Nguyen, Chidera Okeke, Alexander Hoffmann, Quen J Cheng

An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms

NFκB 活性计算器用于描述信号串扰：I 型和 II 型干扰素通过不同的机制增强 NFκB

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2019.01425

Simon Mitchell, Ellen L Mercado, Adewunmi Adelaja, Jessica Q Ho, Quen J Cheng, Gourisankar Ghosh, Alexander Hoffmann

IRF1 cooperates with ISGF3 or GAF to form innate immune de novo enhancers in macrophages.

IRF1 与 ISGF3 或 GAF 协同作用，在巨噬细胞中形成先天免疫新生增强子

IFNÎ³-induced memory in human macrophages is not sustained by epigenetic changes but the durability of the cytokine itself.

IFNγ诱导的人类巨噬细胞记忆不是通过表观遗传变化来维持的，而是通过细胞因子本身的持久性来维持的

GM-CSF receptor expression determines opposing innate memory phenotypes at different stages of myelopoiesis

GM-CSF受体表达决定了髓系造血不同阶段的相反的先天记忆表型

Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks

Dectin-1 配体通过信号网络的差异激活在人类单核细胞中产生不同的训练表型

The Use of Next-Generation Sequencing to Assist in the Diagnosis of Atypical Vasculitis

利用新一代测序技术辅助诊断非典型血管炎

A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes

刺激相关的正反馈回路使 IFN-β 剂量依赖性地激活促炎基因

Stochastic models of nucleosome dynamics reveal regulatory rules of stimulus-induced epigenome remodeling

核小体动力学随机模型揭示刺激诱导的表观基因组重塑的调控规则

NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages

NF-κB动态变化决定巨噬细胞表观基因组重编程的刺激特异性

High Dose IFN- β Activates GAF to Enhance Expression of ISGF3 Target Genes in MLE12 Epithelial Cells

高剂量 IFN-β 激活 GAF 增强 MLE12 上皮细胞中 ISGF3 靶基因的表达

An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms

NFκB 活性计算器用于描述信号串扰：I 型和 II 型干扰素通过不同的机制增强 NFκB