Ramachandran Anup相关文献与解析，生知库

Differential effects on acetaminophen-induced nephrotoxicity and liver injury following modulation of glutathione resynthesis

调节谷胱甘肽再合成对乙酰氨基酚引起的肾毒性和肝损伤产生不同的影响

期刊:Food and Chemical Toxicology

影响因子:3.5

doi:10.1016/j.fct.2025.115896

Etemadi, Yasaman; Akakpo, Jephte Y; Fields, Timothy A; Ramachandran, Anup; Jaeschke, Hartmut

Reactive oxygen species and peroxynitrite in acetaminophen-induced liver injury: Lipid peroxidation and ferroptosis-like cell death

对乙酰氨基酚诱导的肝损伤中的活性氧和过氧亚硝酸盐：脂质过氧化和铁死亡样细胞死亡

期刊:

影响因子:

doi:10.70401/fos.2025.0007

Jaeschke, Hartmut; Ramachandran, Anup

Iron supplementation switches mode of cell death to ferroptosis during acetaminophen-induced liver injury in mice rendering it resistant to N-acetylcysteine.

在对乙酰氨基酚引起的小鼠肝损伤期间，补充铁剂可将细胞死亡方式转变为铁死亡，从而使其对 N-乙酰半胱氨酸产生抗性。

期刊:Toxicology

影响因子:4.6

doi:10.1016/j.tox.2025.154221

Adelusi Olamide B, Venkatraman Aparna, Akakpo Jephte Y, Ramachandran Anup, Jaeschke Hartmut

Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models

对乙酰氨基酚应作为评估与人体相关的体外模型的重要参考肝毒素。

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfae163

Jaeschke, Hartmut; Ramachandran, Anup

毒理研究

发表日期：2025

文献求助收藏

Are New Approach Methodologies (NAMs) the Holy Grail of toxicology?

新方法论（NAMs）是毒理学的圣杯吗？

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfaf113

Jaeschke, Hartmut; Ramachandran, Anup

发表日期：2025

文献求助收藏

4-Methylpyrazole-mediated inhibition of cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity.

4-甲基吡唑介导的细胞色素 P450 2E1 抑制作用可保护肾上皮细胞免受顺铂毒性，但不能保护膀胱癌细胞免受顺铂毒性

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfaf053

Akakpo Jephte Y, Abbott Erika, Woolbright Benjamin L, Ramachandran Anup, Schnellmann Rick G, Wallace Darren P, Taylor John A

细胞生物学

发表日期：2025

文献求助收藏

Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity.

混合谱系激酶结构域样蛋白缺乏会加剧对乙酰氨基酚肝毒性小鼠模型中的早期损伤

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfaf022

Sanchez-Guerrero Giselle, Umbaugh David S, Smith Sawyer H, Akakpo Jephte Y, Jaeschke Hartmut, Ramachandran Anup

The multiple mechanisms and modes of cell death after acetaminophen overdose

对乙酰氨基酚过量服用后细胞死亡的多种机制和方式

期刊:

影响因子:

doi:10.37349/edd.2025.100569

Jaeschke, Hartmut; Ramachandran, Anup

细胞生物学

发表日期：2025

文献求助收藏

Acetaminophen Hepatotoxicity: Paradigm for Understanding Mechanisms of Drug-Induced Liver Injury

对乙酰氨基酚肝毒性：药物性肝损伤机制研究的范例

期刊:Annual Review of Pathology-Mechanisms of Disease

影响因子:34.5

doi:10.1146/annurev-pathmechdis-051122-094016

Jaeschke, Hartmut; Ramachandran, Anup

Imaging bioactive lipid isomers in acetaminophen-induced liver injury using nano-DESI tandem MS.

利用纳米DESI串联质谱对乙酰氨基酚引起的肝损伤中的生物活性脂质异构体进行成像。

Differential effects on acetaminophen-induced nephrotoxicity and liver injury following modulation of glutathione resynthesis

调节谷胱甘肽再合成对乙酰氨基酚引起的肾毒性和肝损伤产生不同的影响

Reactive oxygen species and peroxynitrite in acetaminophen-induced liver injury: Lipid peroxidation and ferroptosis-like cell death

对乙酰氨基酚诱导的肝损伤中的活性氧和过氧亚硝酸盐：脂质过氧化和铁死亡样细胞死亡

Iron supplementation switches mode of cell death to ferroptosis during acetaminophen-induced liver injury in mice rendering it resistant to N-acetylcysteine.

在对乙酰氨基酚引起的小鼠肝损伤期间，补充铁剂可将细胞死亡方式转变为铁死亡，从而使其对 N-乙酰半胱氨酸产生抗性。

Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models

对乙酰氨基酚应作为评估与人体相关的体外模型的重要参考肝毒素。

Are New Approach Methodologies (NAMs) the Holy Grail of toxicology?

新方法论（NAMs）是毒理学的圣杯吗？

4-Methylpyrazole-mediated inhibition of cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity.

4-甲基吡唑介导的细胞色素 P450 2E1 抑制作用可保护肾上皮细胞免受顺铂毒性，但不能保护膀胱癌细胞免受顺铂毒性

Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity.

混合谱系激酶结构域样蛋白缺乏会加剧对乙酰氨基酚肝毒性小鼠模型中的早期损伤

The multiple mechanisms and modes of cell death after acetaminophen overdose

对乙酰氨基酚过量服用后细胞死亡的多种机制和方式

Acetaminophen Hepatotoxicity: Paradigm for Understanding Mechanisms of Drug-Induced Liver Injury

对乙酰氨基酚肝毒性：药物性肝损伤机制研究的范例